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Biomedical subjects

G Cascone

Publications and source records attributed to G Cascone.

8 recordsLinked to original sources
PubMed1994

B-scan echographic measurement of endobulbar foreign bodies.

Echography plays an important role in symptomatology investigations of ocular traumatology. Trauma causes the opacification of eye fluids, and so echography is particularly suitable for studying the endobulbar situation. We wished to enrich ocular investigations with another methodology: ultrasonic evaluation of the dimensions of intraocular foreign bodies, and report here the results obtained with experimental studies introducing foreign bodies into enucleated bovine eyes.

Animals↗
PubMed1992

Ferning test in Down's syndrome.

The tear film was evaluated by the ferning test. We tested tear film in right and left eye on 28 subjects (total 56 eyes), of whom 14 were affected by Down's syndrome, age range 18 to 35 years. The results obtained show that there exists an alteration of the tear ferning in subjects affected by Down's syndrome. We did not find any difference between the right or left eye in each individual. This anomaly could be responsible for frequent infectious pathologies found in the anterior eye segment in these subjects.

Adolescent↗
PubMed1984

[Changes induced by dimethylformamide on platelet function and coagulation activity].

The effect of Dimethylformamide on platelet function and on clotting system has been studied on eight workers exposed to the product, widely used in industry as a solvent of acrylic resins. A significant reduction of the number of the platelets and a drawing out of PTT and PT has been noticed. Such informations has been explained as chronical peripheral use or as modification of phospholipid components induced by DMF instead of synthesis defect, as no significant variation of the fibrinogen and of AT III values, proteins synthetized by liver, has been observed. The platelet aggregation has pointed out, in vivo, a reduction of ADP aggregation in the exposed subjects; in vitro, increasing quantities have determined an increasing reduction of the primary ADP and adrenaline aggregation.

Adult↗
PubMed1984

[Platelet aggregation and resistance to osmotic shock of platelet concentrates obtained by discontinuous-flow cell separation with the surge pump technic].

We studied the ultrastructural morphology and function of platelets collected by apheresis procedure with discontinuous flow using the Surge Pump Technique. The platelet concentrates obtained by this technique are free of erythrocyte and lymphocyte contamination. The platelet morphology as well as the platelet aggregation induced by ADP, adrenaline and collagen of platelet concentrates were similar to those observed in PRP before the apheresis. The response to the hypotonic shock of platelet concentrates was also normal, indicating membrane integrity and good platelet metabolism. These results show that platelet concentrates obtained by the Surge Pump Technique maintain their haemostatic effects and may be infused in thrombocitopenic patients, reducing the risk of alloimmunization related to the presence of erythrocytes and lymphocytes.

Adenosine Diphosphate↗
PubMedDate not supplied

Effects of dimethylformamide (DMF) on coagulation and platelet activity.

The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m3, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.

Adenosine Diphosphate↗