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G Castillo

Publications and source records attributed to G Castillo.

59 records · Page 4Linked to original sources
PubMedDate not supplied

[Environmental contamination with Toxocara sp. eggs in public squares and parks from Santiago, Chile, 1999].

Most of cases of visceral larva migrans syndrome are caused by Toxocara canis larvae. Man acquires the infection by accidental ingestion of ripe eggs of the helminth. In order to find out the frequency of the presence of Toxocara sp. eggs in dog fecal specimens from public places of Santiago city in 1999 july-september a study was carried out in 84 squares and 12 parks from 32 counties. Three fecal samples were collected in each of these places, making a total of 288. Each sample was processed according to a modified Telemann method and three smears of each were microscopically examined. Toxocara sp. eggs were found in 39 (13.5%) fecal specimens. In 28/84 (33.3%) squares and in 8/12 (66.7%) parks these eggs were detected. These results make necessary the control of dogs and cats populations with the aim of reduce the presence of animals without responsible owners. It should be advisable to prevent dogs and cats defecation in public areas grounds, trying to exclude these animals from recreation areas.

Animals↗
PubMedDate not supplied

Pathophysiology of primary distal renal tubular acidosis.

Functional indices of distal acidification were assessed in five unrelated children with primary distal renal tubular acidosis. All patients were unable to lower urinary pH below 6.0 both during ammonium chloride-induced acidosis or after acute i.v. administration of furosemide. In these patients the urine minus blood Pco2 gradient failed to increase normally during acute sodium bicarbonate loading (mean +/- SEM: 5.8 +/- 2.0 mmHg), or after neutral phosphate administration (13 +/- 2.7 mmHg), despite adequate urinary concentrations or bicarbonate (72.2 +/- 14.6 mmol/L) and phosphate (25 +/- 2.3 mmol/L), respectively. They also failed to decrease urine pH below 5.5 with sodium sulfate (7.17 +/- 0.08), but urinary potassium excretion increased significantly. These results strongly suggest that the mechanism responsible for defective distal acidification is a failure of hydrogen ion secretion ("secretory' defect) and not an inability to establish a steep hydrogen ion gradient, as it was formerly believed.

Acidosis, Renal Tubular↗
PubMedDate not supplied

Human genital candidiasis: histochemistry, scanning and transmission electron microscopy.

Exudates from the vagina and uterine cervix of ten patients suffering from genital candidiasis (Candida albicans) were studied with transmission and scanning electron microscopy and with histochemical techniques in order to find the precise location of the Candida infection and to examine the relationship between the vaginal and cervical cells and the infecting yeasts. It was found that Candida species can penetrate, invade, develop and proliferate within the deep layers of intact cells of the cervix and vaginal mucosal epithelium. The presence of mucopolysaccharides in the glycoproteinaceous coat of blastospores and pseudohyphae was demonstrated both outside and within squamous epithelial cells. The importance of the integrity of the glycoprotein coat during the pathogenesis of human infection with C. albicans is therefore emphasized. Furthermore, the histoinvasive yeast apparently produced cytolytic enzymes during its growth within the human vaginal and cervical mucosal epithelium. The intracellular growth of Candida organisms may represent a protective mechanism of the fungus against the host and a manner of resistance to antimycotic therapy.

Candidiasis, Vulvovaginal↗