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Biomedical subjects

G Castrini

Publications and source records attributed to G Castrini.

33 records · Page 2Linked to original sources

Splenectomy in early chronic myeloid leukemia.

The authors report their experience with 25 patients suffering from C.M.L. who underwent splenectomy in an early phase of the disease. There were no operative deaths; seven patients had postoperative complications, three of which required re-operation for intra-abdominal hemorrhage. The follow-up is still too short to permit definite conclusions, but the results so far obtained suggest that splenectomy is useful in reducing leukemic tissue, improving the quality of life, and potentially efficacious in delaying the onset of blastic transformation.

Adult↗

The original Bassini technique in the surgical treatment of inguinal hernia.

Bassini's technique represents a fundamental step in the treatment of inguinal hernia. It can be asserted that a new era in its surgical therapy started with Bassini. As many difficulties exist in comprehending the archaic language used a century ago by the Italian surgeon, the principles of his technique are analysed. It is to Bassini's credit that he invented a simple and easily performed technique to be applied in each case, respecting all the anatomic structures without using any foreign material. Accordingly, it is believed that by using this technique correctly, good results can still be obtained today.

General Surgery↗

Surgical treatment of cancer of the colon.

The authors give a brief review of the course of surgical treatment for colon cancer in the last two decades, as reported in the medical literature. Between 1960 and 1980 they examined 619 patients. Of these, 599 underwent surgery: 436 (72.8%) had radical surgery and 163 (27.2%) received palliative operations. The morbidity was 12.1% and the mortality 2.7%. Sixty per cent of the patients in Dukes' class "A" and "B" were alive after five years, against 28% of those in class "C" and non in class "D". The results obtained during the 1970 to 1980 period are not significantly better than those obtained from 1960 to 1969. On the basis of this experience, the authors describe their present approach for the treatment of tumors of the colon and explain in detail the preoperative preparation of the patients, the extension of the excisions and of the lymphectomies, according to the site of the cancer and its local or distant invasion, the use of temporary derivative colostomies and the application of additional medical therapies. Guidelines for reaching an early diagnosis of colon carcinoma are given, in order to improve the postoperative survival rate.

Adenocarcinoma↗