Biomedical subjects

G Chantrain

Publications and source records attributed to G Chantrain.

23 records · Page 2Linked to original sources

PubMed1989

[Surgery for snoring disorders and sleep apnea syndromes].

Sleep apnea syndrome is a relatively recent notion, frequently associated with snoring. First, a tracheostomy was applied as surgical treatment for the most dramatic cases. Over many years a modified old technic, the uvulo-palato-pharyngoplasty (UPPP) has been applied with a success rate of 60%. This type of surgery seems very easy. Yet anatomic variations require changes in the surgical procedure to obtain an optimal result. This point is frequently not known by inexperienced surgeons. Finally, the complete treatment needs a medical and surgical team able to choose the best solution for each patient, and to follow the obtained results.

Humans↗

PubMed1988

Papillary and follicular thyroid carcinoma. Individualization of the treatment according to the prognosis of the disease.

A retrospective study of a continuous series of 152 patients is presented: the patients were treated between 1 January 1955 and 31 December 1981 for a papillary or a follicular thyroid carcinoma. The prognostic index, proposed by the EORTC Thyroid Cancer Cooperative Group in 1979, was calculated for each patient. According to the survival curves and recurrences after treatment, the study shows a clear-cut difference in prognosis if the prognostic index is below 50 or is equal to or above 50. This observation supports the proposal of minimal treatment for less aggressive tumors and extensive treatment for the high risk patients. The actual treatment plan is: (1) total lobectomy when the tumor is unilateral and the prognostic index below 50, but total thyroidectomy in the other cases; (2) lymph node surgery only in cases of node involvement. Instead of a radical neck dissection, a more conservative procedure should be performed, removing the lymphatic chains and preserving the sterno-cleidomastoid muscle, the internal jugular vein and the spinal accessory nerve; (3) no postoperative radioiodine for low risk patients with complete removal of the tumor; (4) postoperative thyroid hormone at doses suppressing secretion of TSH for all patients.

Adolescent↗

PubMed1988

Antimicrobial prophylaxis for major head and neck surgery in cancer patients.

A total of 113 patients were randomly allocated to receive either ticarcillin plus clavulanic acid (total dose, 20.8 g) or clindamycin (total dose, 2.4 g) plus amikacin (total dose, 1 g) as perioperative antimicrobial prophylaxis for major head and neck surgery. The two groups were similar in age, prior antineoplastic treatment (surgery, chemotherapy, and radiotherapy) or tracheostomy, and the various types of surgery including radical neck dissection. The wound infection rate was 10% in the group of patients receiving clindamycin plus amikacin and 36% in the group receiving ticarcillin plus clavulanic acid (P less than 0.05). Initiation of systemic antibiotic therapy within 15 days of surgery was necessary for 20 and 45% of these patients, respectively (P less than 0.05). The distribution of microorganisms causing wound infections was comparable in both groups, except for anaerobes, which were isolated predominantly from patients who had received ticarcillin plus clavulanic acid.

Adult↗

PubMed1988

[A case of (benign) teratoma of the nasopharynx].

The authors relate a case of a benign tumor (teratoma) sitting in the nasopharynx of a 10-year-old boy. A short review of the literature is presented: speculations over the origins of these tumors, possible diagnosis, treatments... The authors insist on the necessity of realizing some investigations (X-rays, fibro-endoscopy) when regarding a posterior nasal obstruction.

Child↗

PubMedDate not supplied

[Microsurgery and free flaps as indications for the reconstruction of the mouth and pharynx region following tumor resection].

This article describes the microsurgical approach of the head and neck team of the Bordet Institute. During a period of 2 1/2 years 35 free flaps, 71 Pectoralis Major and 9 local flaps were performed for oropharyngeal reconstruction. Different types of free flaps were used and analyzed: 15 latissimus dorsi myocutaneous, 8 radial forearm, 1 gastric, 3 jejunum, 2 crista iliaca osteocutaneous, 1 scapular osteomyocutaneous, 3 scapular osteo-muscular of a new type (discovered in our department), 1 serratus anterior muscular and 1 flap composed of 3 others (a latissimus myocutaneous, a serratus anterior and a scapular osteo-muscular flap). 60% of the microvascular anastomoses were performed in a previously heavily irradiated area and none failed. The indications of some of these flaps are discussed and summarized.

Bone Transplantation↗