PubMed Health⌕ Search

Biomedical subjects

G Chavanne

Publications and source records attributed to G Chavanne.

12 recordsLinked to original sources

[Diagnostic value of clustered microcalcifications discovered by mammography (apropos of 227 cases with histological verification and without a palpable breast tumor)].

UNLABELLED: Excisions with histological examination were performed in 227 cases of breast microcalcifications without palpable tumor. 99 benign lesions, 27 borderline lesions and 101 carcinomas, 58 of them in situ, were found. Different radiological parameters were studied in relation to histological results: According to the morphology of the calcifications, a classification of 5 types was made. Type 1: annular: 100 per cent were benign lesions. Type 2: regularly punctiform: 22 per cent were malignant lesions. Type 3: too fine for precizing the shape: 40 per cent were malignant lesions. Type 4: irregularly punctiform: 66 per cent were malignant lesions. Type 5: vermicular: 100 per cent of the lesions were malignant. The number of calcifications was higher in carcinomas and 56 per cent of the lesions with more than 30 calcifications were malignant. Close grouping: when there were more than 10 calcifications within a 5 mm diameter area, 57 per cent of malignant lesions were found. Several clusters: 70 per cent were correlated with malignant lesions. Uneven sizes: no signification. LOCATION: the rare retroareolar location correlated with benign lesions in 64 per cent of the cases. Furthermore, the malignant lesions were rare (24%) in women under 40 years of age. For these young women, the authors suggest to directly excise the most suspicious microcalcifications as based on the factors of suspicion and to simply follow the other cases.

Adult↗

[Maxillofacial radiation-induced cancers (author's transl)].

Radiation-induced cancers are fortunately a very rare complication of radiotherapy for cancers. Sagerman, however, reported 21 cases in a series of 243 patients with retinoblastomas, examined after a period of at least 5 years, and 6 cases were observed in a similar series of 112 children seen at the Curie Institute. This report describes 10 cases of irradiation-induced cancers of the maxillofacial region seen at the Curie Institute over a period of 30 years. The exceptional nature of this risk is such that it cannot represent a contra-indication to irradiation therapy of a malignant tumor, especially now that low-energy radiation has been abandoned, and with the modern therapeutic procedures available. The risks of cancer are greater, however, after irradiation of benign bone lesions and benign affections of the cervico-facial region. Treatment of these benign affections in children or young adults by low or reduced doses of conventional low-energy radiations should be forbidden, and the indication for treatment with radiations, which must be of high voltage, should be exceptional.

Adolescent↗

[Lymphographic evaluation of cervico-uterine carcinoma (author's transl)].

Bilateral pedial lymphography is a technique which has already been long employed and which had aroused great hopes in the detection of metastatic node involvement. The method has nevertheless failed to form an invariable part of the pretherapeutic assessment of cervico-uterine carcinomas. This attitude may be easily explained by the difficulties encountered in the interpretation of lymphographies as indicated in the first publications. New data nevertheless have made it possible to refine the method. Whilst false negatives remain inevitable in almost half the cases with histological evidence of involvement, false positives may be reduced to a minimum by very strict criteria of interpretation. Lymphography, a harmless technique, can then provide valuable information which enables the surgeon to confirm the success of his lymph node dissection and the radiotherapist to define areas requiring treatment. It is of major prognostic value. It may be used to guide transparietal lymph node biopsies and secondary detect lumbo-aortic nodes.

Female↗