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Biomedical subjects

G Chesher

Publications and source records attributed to G Chesher.

6 recordsLinked to original sources
PubMed1995

Biopsychosocial changes associated with cessation of cannabis use: a single case study of acute and chronic cognitive effects, withdrawal and treatment.

A 35 year old male was cognitively assessed prior to cessation of 18 years of daily cannabis use and monitored for several weeks post cessation. Brain event-related potential (ERP) measures of selective attention reflecting a difficulty in filtering out complex irrelevant information showed no indication of improvement over 6 weeks of abstinence. In contrast, when tested in the acutely intoxicated state prior to cessation of use, a dramatic normalisation of the ERP signature of this individual was observed. A treatment program based on supportive-expressive psychotherapy was administered and depression, anxiety and general psychological health were monitored over the course of withdrawal from cannabis.

Action Potentials↗
PubMed1993

Investigation of the "hangover" effects of an acute dose of alcohol on psychomotor performance.

Performance on some complex and difficult tasks has been shown to be negatively affected for some time after an acute dose of alcohol has been cleared from the system. However, Dauncey reported impairment of a relatively simple reaction time task 3 hr after a dose of alcohol, when the blood alcohol concentration was at or near 0. This impairment was positively related to the subject's drinking history. A replication using the same task found a linear dose/impairment relationship during intoxication. A second simple reaction time task and a vigilance task showed a trend toward impairment, but only a divided attention task was significantly affected during intoxication. There was no significant effect of dose on any of these tests during a "morning after" session. The results are discussed in relation to the differences in method between Dauncey and this study.

Adult↗