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Biomedical subjects

G Chevalley

Publications and source records attributed to G Chevalley.

4 recordsLinked to original sources

[Apropos of a case of bilateral perforating corneal ulcer in a patient with Portugese amyloidosis].

PURPOSE: Corneal ulcer is a very rare clinical manifestation in hereditary familial amyloidosis of the Portuguese type, from which only one case has been reported previously. The case of a 35-year-old man illustrates the diagnostic findings and the difficulties encountered in understanding the physiopathology of such a complication. PATIENT: The patient was referred by his general practician because of bilateral visual impairment since few days. Examination disclosed bilateral central perforating corneal ulceration. Corneal sensitivity was normal in both eyes, BUT (break-up time) was 2 sec. and Schirmer II test abolished. RESULTS/CONCLUSION: Corneal ulceration is an unusual complication consecutive to a massive dry eye syndrome.

Adult↗

[Foldable implants in cataract surgery at the Geneva Ophthalmological Clinic].

PURPOSE: Since 1993, foldable intraocular lenses (Adatomed 90 D, Allergan SI26NB et SI30NB, Chiron C10, Medilas 127) have been implanted through a corneal or scleral tunel after phakoemulsification of the cataract. This retrospective study is made for evaluating the advantages and the disadvantages of these new silicon implants. PATIENTS AND METHOD: The first 250 implantations of a silicon foldable lens compared to 50 rigid PMMA lenses. Problems during implantation, final visual acuity, opacification of the anterior and posterior capsule, decentration of the lens and the stability of the refraction during the 3-19 months following cataract extraction were evaluated. RESULTS: 4 breaks of the capsule, 2 desinsertions of the capsular bag during the implantation of a foldable lens, a difference of less than 0.5 diopter in favour of the foldable lenses, no difference in the incidence of the secondary cataract (p = 0.3) and a more marqued postoperative opacification of the anterior capsule (p = 0.0275) among the foldable silicon lenses were observed. CONCLUSIONS: These results are very encouraging for the visual outcome, but the time of postoperative observations is too short to determine on a long term basis, which is the most important factor for a new implant. To avoid an early opacification of the anterior capsule, a large capsulorhexis, as wide as the optic of the silicon lens, is recommended.

Adolescent↗

[Uveitis complicating posterior segment neovascularization. Six cases].

Subretinal or preretinal neovascularisation may be occasionally observed during the evolution of certain forms of uveitis. Subretinal neovascularisation commonly begins at the level of the chorioretinal uveitic scars. Consequently, the alteration of the retinal pigment epithelium-Bruch's membrane-choriocapillaris complex is the apparent cause. Laser photocoagulation of the neovascular front, when indicated, is the treatment of choice. In contrast, preretinal neovascularisation is observed at the active stage of uveitis. Fluorescein angiography findings suggest that it is probably correlated with the importance of inflammation since in most of the cases there is no retinal ischemia. Therefore, in order to obtain a regression of the neovascular tufts the treatment should be directed against the inflammatory process. In this study the authors report five cases of subretinal neovascularisation which developed at the level of chorioretinal post-inflammatory scars and one case of papillary neovascularisation which occurred during the active stage of an unilateral intermediate uveitis and in which new vessels regressed completely following systemic steroid treatment.

Adolescent↗