PubMed Health⌕ Search

Biomedical subjects

G Ciliv

Publications and source records attributed to G Ciliv.

At least 37 records · Page 2Linked to original sources
PubMed1976

In vitro histamine release from leukocytes in penicillin allergies.

The definite diagnosis of Type I allergy against penicillin is very important. The in vivo tests used for this purpose may have some disadvantages for the patient. Among the in vitro tests used for the evidence and differential diagnosis of Type I allergy against penicillin, the determination of histamine release from leukocytes and the detection of IgE by the RAST test are the most promising. We have used the test of histamine release from leukocyte in this study of 18 cases, nine of whom had Type I hypersensitivity reactions to penicillin and comprised the study group, the rest were control cases. The per cent of histamine release in the control group was "zero" while in the study group it ranged from 3.9 to 51.7 per cent. The results indicate that the method used in this study is a sensitive and reliable method for the diagnosis of Type I penicillin allergies.

Adolescent↗
PubMedDate not supplied

The effects of immobilization stress on electrodermal activity and brain catecholamine levels in rats.

The effects of immobilization stress on electrodermal activity (EDA); skin conductance response magnitude and rate, skin conductance level and habituation number, and brain catecholamine levels; norepinephrine (NE) and dopamine (DA) were investigated in rats. Electrodermal activity was recorded using constant current method. Brain catecholamine levels were determined by a spectrophotophlorometric method. Electrodermal activity parameters (except skin conductance level) increased during immobilization. It was observed that, during immobilization stress, the alteration of norepinephrine and dopamine levels in rat brain was related to cerebral region and the duration of immobilization stress. It was concluded that these electrodermal activity alterations can be attributed to the changes in central norepinephrine metabolism induced by immobilization.

Animals↗
PubMedDate not supplied

Breast milk beta-glucuronidase levels in hyperbilirubinemia.

Breast milk beta-glucuronidase was thought to be one of the etiological factors in the pathogenesis of late-onset breast-milk jaundice, but results of these studies are conflicting. In this study breast milk beta-glucuronidase levels were determined in groups with physiologic jaundice, early breast-feeding jaundice and late breast-milk jaundice. No difference in beta-glucuronidase levels of these three groups was found in samples taken on the 4th and 15th days of life. beta-glucuronidase activity in breast milk declined from the 4th to 15th day in all groups. These results imply that factors other than breast milk beta-glucuronidase activity should be investigated to reveal the pathogenesis of late-onset breast-milk jaundice.

Glucuronidase↗
PubMedDate not supplied

Lipids and lipoproteins in the sexual maturation stages of male adolescents.

The study population consisted of 144 healthy, non-obese male adolescents, aged between 11-18 years, who were in different stages of sexual maturation as described by Tanner. The fasting plasma cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (C-HDL), low density lipoprotein cholesterol (C-LDL), and very low density lipoprotein cholesterol (C-VLDL) levels were calculated for each subject. There were significant differences observed in the following: mean TC levels between G1 and G2; mean C-HDL levels between G2 and G3 and between G3 and G4; mean TG levels between G1 and G2 and between G2 and G3; mean C-LDL levels between G1 and G2, and mean C-VLDL levels between G1 and G2 and between G2 and G3. There were no significant differences for lipids and lipoproteins between the prepubertal (G1) and postpubertal (G5) stages. It is generally believed that testosterone may play a role in mediating lipid and lipoprotein levels in the pubertal phase, but, since we found no significant differences in the levels of lipids and lipoproteins between G1 and G5, and also because these levels fluctuated from G1 to G5, it strongly suggests that the effect of testosterone on lipids and lipoproteins is dependent on other factors such as hormones, dietary habits, age, race, etc.

Adolescent↗
PubMedDate not supplied

Tay-Sachs disease: a case report.

Tay-Sachs disease (GM2 gangliosidosis I) is an autosomal recessive lysosomal-storage disorder confined to the central nervous system, resulting from deficiency of hexosaminidase A. The case presented is of a twelve-month-old girl brought to the hospital because of mental-motor deterioration and convulsions. She was the child of first cousins and had a history of the deaths of two siblings with the same manifestations. Generalized hypotonia, macrocephaly, hyperacusis and a retinal cherry red spot appearance were present. There was no organomegaly. The diagnosis of Tay-Sachs disease was made by means of absence of serum hexosaminidase A activity.

Age of Onset↗