[Bioavailability of adenylic and pyridinic compounds in normal human gingiva].
Explore the source record for details and available documents.
Adenine Nucleotides↗
Biomedical subjects
G Cocchi
Publications and source records attributed to G Cocchi.
[Genito-urinary malformations in a regional survey in Emilia Romagna].
In a multicentric survey carried out in Emilia Romagna area on congenital malformations 1914 babies out of 103484 babies born from 1978-1984 were discovered to have malformations. Out of these malformations cases 17% were found to be affected by genitourinary tract anomalies (GU) divided as follows: 235 genital malformations and 91 urinary tract anomalies. All these GU patients were diagnosed within the first week of life. Genital malformations: Genital malformations are mainly constituted by hypospadias, found in 214 out of 235 babies. Among these babies, 72% have first degree hypospadias, 22.4% have second degree, and only ten babies were found with third degree hypospadias. In this study 4.1 out of 1000 male newborns have been found affected by hypospadias, in agreement with the results of other researches whose values were between 2% and 4.4%. Many different variables (such as parental age, exposure to smoke, alcohol, RX-ray before pregnancy, low birth weight, early age at menarche, exposure to progestins for threatened abortion, shorter gestation) have been considered in order to verify their correlation with the hypospadias, comparing with control group. Among these the most statistically significant are the exposure to progestins for threatened abortion (p less than 0.05), early age at menarche (p less than 0.001) and the intrauterine growth retardation (p less than 0.001). Also these results agree with the previous studies. Urinary tract anomalies: the 93 babies with kidney and-or urinary tract malformations out of 103484 newborns represent the 8.9%. The diagnoses were made or suspected (and later confirmed) during the first week of life.(ABSTRACT TRUNCATED AT 250 WORDS)
Female↗
Ultrasonographic appearance of the mega cisterna magna in the newborn.
The mega cisterna magna is a congenital developmental malformation which in the majority of instances is symptomless and does not require further study or surgical treatment. However, differential diagnosis with other cerebellar diseases is often necessary especially in newborn infants. Ultrasonographic recognition of the mega cisterna magna in a newborn infant is reported. The reported case demonstrates the usefulness of the ultrasonographic technique in the study of the posterior cranial fossa abnormalities of newborn infants.
Cisterna Magna↗
[The Emilia-Romagna Abnormalities Study Group: coverage and geographic distribution of congenital abnormalities in Emilia-Romagna].
Systems for monitoring Congenital Malformations (C.M.) have been taken up by most Countries, even though there is great diversity in the methods of data collection. In Italy nothing existed until 1977. In 1978 in the Emilia-Romagna Region an epidemiological Program began for the surveillance and monitoring of all C.M. diagnosed in the first 7 days of life in the newborn babies and in the stillbirths of over 28 weeks of gestational age. After three years of monitoring-1978 to 1980-we have reached the baseline data which is the fundamental prerequisite to ensure comparability of data from different centers and within our region in different periods too. The incidence of all C.M. was 1.9% in the first three years of monitoring with no statistical difference from year to year or between the Districts of the Region. For six selected C.M. we studied the incidence in the Region and also in the four Districts starting from 1978. Our data is comparable to that reported in the other Countries but we observed high incidence of Down Syndrome (17.2 per 10,000 births that is one of the highest values detected = 1 case every 582 newborn babies). For hypospadias we observed, starting from the second quarter of 1980, a progressive increase that dropped however in the first quarter of 1981. No etiologic clues have yet been revealed.
Congenital Abnormalities↗
[The VACTERL association and its nosologic limits].
We present six cases of V.A.C.T.E.R.L. association diagnosed by the Study Group of Congenital Malformations in Emilia Romagna (I.M.E.R.) from january 1978 to december 1981. With regard to the etiology, the pregnancy history of these six cases does not support the hypotesis of the progestin-estrogen compounds as possible teratogenic factors of the V.A.C.T.E.R.L. association. Furthermore the familial recurrence hypotesis of this complex needs further detailed studies. At last we attempt to specify the nosological limits of the V.A.C.T.E.R.L. association respect to other similar malformative complexes as the Caudal Regression Syndrome, Rokitansky Syndrome, Holt-Oram Syndrome and Potter Syndrome.
Abnormalities, Multiple↗
[Clinico-statistical features of perinatal and early neonatal mortality].
Perinatal and neonatal mortality rates are considered to be among the most sensitive measures available for monitoring the health of population and consequently have been assumed, too, to reflect primarily the capacity of the obstetricians and pediatricians. Perinatal mortality is here defined as stillbirths (or late fetal deaths) plus early neonatal deaths, that is, it includes fetuses born dead after 28 completed weeks of pregnancy and liveborn infants who died before the completion of the first week after birth. This report is concerned with the variation in neonatal mortality observed at the Istituto Clinico di Puericultura, Bologna University in a period from 1971 to 1981 and in perinatal mortality from 1976 to 1981 only. In this period reductions in stillbirths (from 12.5% to 7.8%) and early neonatal mortality (from 13.2% to 7.0%) are recorded. The decrease in the perinatal mortality rate, which occurred at the Obstretic-Neonatal Unit of Bologna University (dropping from 25.6% in 1976 to 14.8% in 1981) may be attributed to a comparable reduction in stillbirths and early neonatal mortality due to better health services and a more modern pattern of medical care. More attention must be given to that particular group of newborn babies weighing 1,500 gm or less (VLBW Infants) which accounted for about 40% of all the neonatal deaths.
Female↗