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Biomedical subjects

G Colnet

Publications and source records attributed to G Colnet.

24 records · Page 2Linked to original sources
PubMed1979

Benign intracranial hypertension. A clinical evaluation of the CSF absorption mechanisms.

Fifteen patients suffering from Benign Intracranial Hypertension due to various causes were investigated by measuring the CSF resistance to flow, and the pressure difference between the CSF and the sagittal sinus. Isotope cisternography was also performed, and the patency of the dural sinuses was checked by both sinography and phlebography. In twelve the results confirm a defect in the resorption mechanism, the nature of which proved to be venous in six, and linked to impairment of subarachnoid villi in six others. Three patients could not be classified. The significance of normal isotope cisternography is discussed.

Cerebrospinal Fluid↗
PubMed1978

Intracranial pressure with intracerebral hemorrhages.

Intracranial pressure was recorded continuously during an average of 15 days in 17 patients suffering from primary intracerebral hemorrhage. In 12 cases the highest pressures were recorded just after the stroke; then the intracranial pressure decreased and became normal in an average of 20-30 days. Other patterns of evolution were less often observed: a rapid and lethal elevation of pressure in one case, a constantly low pressure in two, and a stagnant evolution with moderate hypertension in two others. Secondarily developing intracranial hypertension was never observed during the monitoring period. Evacuation of the clots was performed in six patients. This only slightly shortened the course of the increased intracranial pressure. It is concluded that intracerebral hematoma appears as an expanding lesion only during the time of its formation. The prognosis depends more upon the destructions by the hemorrhage than upon the increased pressure. Nevertheless, true hypertension is possible. Knowledge of intracranial pressure in the course of intracerebral hemorrhage is important in deciding whether the treatment is to be surgical or conservative. Measurements of the intracranial pressure in our practice has reduced the number of interventions, with identical or slightly improved results.

Adult↗
PubMed1973

[Palatal cylindroma].

Explore the source record for details and available documents.

Carcinoma, Adenoid Cystic↗
PubMedDate not supplied

Pharmacokinetics of cefotaxime and its desacetyl metabolite in plasma and in cerebrospinal fluid.

The aim of the study was to investigate the pharmacokinetic modelling of Cefotaxime (CTX) and its main metabolite Desacetyl Cefotaxime (DCTX) which has a less antibacterial activity than the CTX. After intravenous administration of 1g of CTX to 26 patients, the plasma concentrations determined by HPLC showed that the pharmacokinetics of CTX and transformation to DCTX can be described with an open five-compartment model. The implications of this are discussed from the clinical point of view.

Adolescent↗
PubMedDate not supplied

[A module of statistical analysis of the intracranial pressure: the S.A.I.C.P. system].

This paper describes an automatic system designed so as to provide a statistical analysis of I.C.P. (A.S.P.I.C. System). It functions on line at the patient's bedside, in connection with any electromanometer. It issues, after an acquirement period of 24 hours or less, three different informations: 1) the pressure class frequency distribution or histogram, 2) the modal pressure, that is to say the most frequent pressure, and 3) two standard deviations which measure the dispersion of the right and left part of the histogram. The meaning of those informations are reminded, according to anterior researchs, and some illustrations of A.S.P.I.C. System applications are presented.

Computers↗