Symptomatic atrial fibrillation as the first symptom of a giant left atrial appendage aneurysm.
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Biomedical subjects
Publications and source records attributed to G Conradi.
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The enteric transport kinetics of peroral applied D-xylose was comparatively analysed with help of a modified D-xylose absorption test in man and in experimental pig. The animal experimental investigations were carried out in 10 female hybrid pigs at the age of 3 to 8 months. The absorption quickness and the dimension of the effective small intestine absorption in dependence on the time does not show any statistically significant differences between both biological systems. On the other hand the experimental animals show a statistically secured higher elimination quickness of D-xylose in contrast to the comparison group of healthy adults.
In case of absorption examinations in younger and advanced age it is necessary to differentiate between involutively conditioned alterations of enteral absorption and those ones conditioned by morbidity. For this purpose the modified D-xylose-absorption test offers itself as a diagnostical remedy. The equivalently characteristic alterations in absorption kinetics of carbohydrates in cases of the occurrence of an obstructive jaundice, in patients in the stage of generalisation of carcinomatous disease and in the elderly may be demonstrated by the modified D-xylose-Test.
Oral feeding administering a balanced synthetic diet (defined diet, space diet) is increasingly used in clinical practice. the influence of this completely ballast-free and total absorbable diet on the function of the small gut ist nearly unknown. By means of the modified D-xylose-test a reduction of the D-xylose resorption could be stated. The degree of this reduction is without clinical importance.
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The rapid loss of the body weight of oncological patients in the advanced stage of the carcinomatous disease is caused by numerous pathophysiological mechanisms. With the help of the modified D-xylose absorption test was investigated which value have disturbances of the enteral absorption in the complex of causes for the development of a tumour cachexia. For the patients in the stage of generalisation of the carcinomatous disease clear disturbances in the enteral food intake could be proved in contrast to patients with carcinoma without general tumour symptomatology and healthy persons. The influence of chemo- and radio-therapy on the enteral absorption of patients with carcinoma was discussed. The forced alimentation of oncological patients with unspezific tumour symptoms must be regarded as a firm constituent in the treatment of patients with carcinoma.
The postoperative resorption in the small intestine after cholecystectomie was found out by means of the modified D-xylose resorption test on the 2-th, 4-th, 6-th an 8-th postoperative day for 14 patients. The velocity and the dimension of the enteral resorption of D-xylose was lower in the immediate postoperative phase. The dimension of the D-xylose resorption was normalized on 4. p. o. day and obtained the preoperative starting-value on the 8-th postoperative day. The myoelectrical activity of the small intestine normalized in a shorter time after cholecystectomy than the enteral resorption. A formal parallelism consists between the normalisation of the motoric activity of the stomach and the xylose-resorption in the immidiate postoperative phase. For the small intestine resorption in the postoperative phase completely clarified and required further investigations. The influences of electrolyte displacement and disturbances of the microcirculation in the postoperative period in the small intestine resorption were discussed.
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