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G Coppi

Publications and source records attributed to G Coppi.

213 records · Page 12Linked to original sources
PubMedDate not supplied

Effects of SF-482 on bile, gallstones formation and experimental hyperlipemias.

The effects of 3 alpha, 7 beta-dihydroxy-12-cheto-cholan-24-oic acid (SF-482) were compared with those of ursodeoxycholic acid on bile flow and composition, on gallstones formation and on experimental hyperlipemias. SF-482, like ursodeoxycholic acid, increases the bile flow and residue in normal and ethynylestradiol-treated rats. The two compounds increase the biliary excretion of bile acids and phospholipids with a desaturation of bile cholesterol. SF-482 and ursodeoxycholic acid decrease the incidence of gallstones in mice; both compounds are active in Triton WR-1339, in olive oil and margarine hyperlipemias in rats and in ethanol intoxication in mice. In general, SF-482 is more active than ursodeoxycholic acid.

Alcoholic Intoxication↗
PubMedDate not supplied

[Carotid endarterectomy using the classical technique and by eversion].

After a brief introduction on the history of the surgical treatment of carotid stenosis the authors illustrate both the classical endarterectomy and the eversion endarterectomy. The constant search for a technique which could be of easy execution and also reduce the risk of complication (especially late ones, such as restenosis), brought the authors to adopt the eversion endarterectomy with reimplantation of internal carotid artery. From 1990 through 1995, 1034 carotid endarterectomies were performed, of which 611 with eversion technique and 423 with others techniques. The average follow-up was 38 months. The eversion endarterectomy group had lower neurological morbidity and mortality rates, both early and late. Even more important, they had a lower incidence rate of hemodynamically relevant restenosis (0.37% in the eversion endarterectomy group vs 1.97% in the other group).

Adult↗