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Biomedical subjects

G Cornand

Publications and source records attributed to G Cornand.

At least 19 recordsLinked to original sources

Corneal blindnesses in tropical environment.

Corneal blindnesses make up a main public health problem in numerous developing countries where they constitute a sign of low sanitary level. The main diseases which cause corneal blindnesses are: Trachoma. Xerophthalmia. Measles. Corneal ulcerations and keratitis. Onchocercosis. Neonatorum ophthalmia. Leprosy. Injuries. Some therapeutic practices. Epidemiological analysis leads to the definition of risk groups: Small children. Isolated rural communities. Unhealthy urban communities. Out of place populations. Under-fed populations. Only a joint prevention can be able to fight against this social, economic, a human plague constituted by corneal blindnesses. Simple prevention measures which are often not very expensive, showed their efficiency. They are as follows: Individual and collective hygiene measures. Improvement of alimentary conditions. Earliness and quickness in ocular care. Vaccination against measles. Improvement of the care to mother and child. Sanitary education for prevention. These prevention tasks are supported by the health workers who are spread out inside the population. Their formation, the means they are granted with constitute a main priority which has to be taken into account in the choices and the decisions to be made in order to fight against blindness linked with cornea opacification with efficacy.

Blindness↗

Pterygium. Clinical course and treatment.

The author reviews the current concepts of the pathogenesis, clinical course and treatment of pterygium. This neoplasm can be considered as to be a manifestation of a chronic irritative process caused by solar radiation and repeated microtrauma and, to a lesser degree, by other aetiological factors which are studied successively. The clinical course of the disease consists of two phases: a conjunctival phase and a corneal or true pterygial phase. The anatomical and clinical forms studied in a population of 2,350 subjects in an endemic region of pterygium (Central Sahara) appear to be closely related to the severity and the duration of exposure to predisposing factors. Prevention therefore constitutes the best treatment when it can be applied in highly endemic zones. The various preoperative and postoperative medical and physical treatment modalities (radiotherapy--beta therapy--cryotherapy--laser photocoagulation--antimitotic drugs--corticosteroids) are analysed together with the three main groups of surgical techniques: deviation--excision--lamellar keratoplasties. Medical and physical treatment modalities appear to be minimally effective in the primary treatment, but are valuable and essential adjuvants to surgical treatment. Surgery is the only treatment modality indicated in the corneal phase of the disease. Recurrence remains the major risk of this surgery which means that the surgical indications must be very carefully defined. Only a small number of techniques can be considered to be valid. Lamellar keratoplasties and their variants are indicated in the great majority of cases and have demonstrated their efficacy in the prevention of postoperative recurrences.

Female↗

[Comparative study of fungicidal activity in vitro of various quaternary ammonium compounds used in ophthalmology].

A study was conducted to evaluate the antifungal activity in vitro of 5 quaternary ammonium compounds. N cetylpyridinium was found to be particularly active against Candida albicans and Aspergillus fumigatus. The association of N cetylpyridinium and of neosynephrine, found in various eye drop compositions, resulted in potentation of the antifungal activity of this quaternary ammonium.

Antifungal Agents↗