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Biomedical subjects

G Cowan

Publications and source records attributed to G Cowan.

25 records · Page 2Linked to original sources

Plasma glutamine levels and falciparum malaria.

Glutamine deficiency is associated with increased rates of sepsis and mortality, which can be prevented by glutamine supplementation. Changes in glutamine concentration were examined in Ghanaian children with acute falciparum malaria and control cases. The mean (SD) plasma glutamine concentration was lower in patients with acute malaria (401 (82) mumol/L, n = 50) than in control patients (623 (67) mumol/L, n = 7; P < 0.001). Plasma glutamine concentrations all rose in convalescence. The mean (SD) increase in plasma glutamine was 202 (123) mumol/L (n = 18; P < 0.001) compared with acute infection. We conclude that acute falciparum malaria is associated with large decreases in plasma glutamine and these falls may increase susceptibility to sepsis and dyserythropoeisis.

Case-Control Studies↗

Comparison of lifestyles among obese and nonobese African American and European American women in the community.

BACKGROUND: Gender and race differences in preventive health behavior have been examined in several studies. A few race- and gender-specific studies of health-promoting activities have been conducted although none of these specifically addresses race, female gender, obesity, and health-promoting activities. Such a study would fill an important gap in the literature. OBJECTIVES: To examine the effects of race and obesity on health-promoting behaviors in women. METHOD: A comparative descriptive design was used with two levels of body size (obese and nonobese) and two levels of race (African American and European American). RESULTS: Obese women scored lower than nonobese women on all Health-Promoting Lifestyle Profile (HPLP) scales. African American women scored lower than European women only on nutrition. CONCLUSIONS: Health promotion counseling should be considered for all obese women because obesity may be a mediating variable between race and health-promoting behaviors.

Adult↗

Appraisal: purpose, pitfalls and good practice.

This article is based on the proceedings of the conference 'Appraisal: purpose, pitfalls and good practice,' held at the Royal College of Physicians of London in May 1996. The conference brought together not only doctors but also representatives of other professions, to review the role of appraisal in education and industry, and to discuss how it might be applied in the medical field.

Employee Performance Appraisal↗