PubMed Health⌕ Search

Biomedical subjects

G Cozzi

Publications and source records attributed to G Cozzi.

At least 91 records · Page 5Linked to original sources
PubMed1983

[Histiocytosis X: radiologic evaluation of 52 patients].

Fifty-two patients with histologically proven histiocytosis X and intrathoracic and/or bone lesions have been evaluated. In the group, bone lesions appear clearly prevalent (51/52 patients) mainly as localized monostotic disease (31/51). Flat bones were more frequently involved, with special evidence for skull and ribs. Short as well as long bones were only seldom compromised, almost only in polyostotic and generalized disease. On the basis of our experience the most suggestive radiological findings in bone to diagnose an histiocytosis X were the following: preferential involvement of a flat bone, osteolytic pattern, sharp borders (72.9%), rare evidence of pathological fracture (20%) and periostitis (10%). On the contrary, the involvement of the neighbouring soft tissues (38.8%) appears to be significant.

Adolescent↗
PubMed1983

[Antithrombin III and fibrinogen after surgical interventions on the abdomen and heart].

We have explored the changes of plasma concentrations of antithrombin III and fibrinogen in patients recovering from major abdominal and cardiac surgery. In one group of patients subjected to major abdominal surgery we detected a statistically significant reduction of antithrombin III in the second and third postoperative day, followed by return to normal values in the fourth or fifth day. Fibrinogen, instead, increased to as much as 180% of the preoperative value in the first four postoperative days and reverted slowly to preoperative values between the fourth and the eighth day. In another group of patients subjected to cardiac surgery procedures utilizing the heart-lung machine, however, we found no significant reductions of antithrombin III in the early postoperative period. These results suggest the possible influence of local tissue factors affecting the plasma levels of antithrombin III differently in the two types of surgery under discussion. The patients subjected to extracorporeal circulation, on the other hand, showed a depletion of plasma fibrinogen down to less than 30 or 40% of preoperative values. This may reflect activation of coagulation processes and the considerable sequestration of fibrin at some interfaces of the heart-lung machine.

Abdomen↗
PubMed1982

Oophorectomy in advanced breast cancer: clinical radiologic correlations.

The radiograms of the chest and skeleton of 49 patients with advanced breast cancer treated with bilateral ovariectomy were reviewed. The modifications in the secondary localizations and/or their appearance after castration were compared with the findings of the clinical examination. Appearance or progression of intrathoracic lesions, like the appearance or progression of osteolytic lesions, corresponded to a progression of the disease in other sites. Osteoblastic evolution of osteolytic lesions and the appearance of osteoblastic lesions in bones undamaged before ovariectomy were signs of a favorable response to therapy. The response of chest and bone metastases is usually rather early, and the first radiographic survey should be performed about 3 months after ovariectomy.

Bone Neoplasms↗
PubMed1982

[Radiological examination of the colon resected for neoplastic pathology in the study of complications and recurrence of the disease].

After resection for cancer of the large bowel, because of high incidence of recurrences, careful radiological examinations must be performed during the follow-up. From the experience of more than 1800 X-ray examinations, after large bowel surgery, the authors describe the roentgen findings, pointing out pathological changes. Roentgenographic findings are distinguished considering the interval between surgery and X-ray examinations (early surveys and late surveys) and their site (anastomosis, residual colonic loops, perivisceral tissues). The main diagnostic problem usually arises in the late surveys at the anastomosis where is often difficult to distinguish a late surgical complication from a neoplastic relapse. This diagnosis is easier by comparison with films from early postoperative examinations. If they are not available correct diagnosis is yet often possible looking for some radiological signs which are carefully described.

Colonic Neoplasms↗
PubMed1981

Lymphomatous involvement of intrahepatic and extrahepatic biliary ducts. PTC and ERCP findings.

The intra- and extrahepatic biliary ducts were examined by endoscopic retrograde cholangiopancreatography or percutaneous transhepatic cholangiography in 10 patients with malignant lymphoma and suggested hepatic involvement. Different radiologic appearances of the biliary tract are described, related to lymphomatous involvement of the liver or extrahepatic tissues, and compared with laparoscopic findings and final diagnosis. The results demonstrate the accuracy of cholangiography by PTC and ERCP and its usefulness in patients in whom non-invasive techniques fail to provide a reliable diagnosis.

Bile Duct Neoplasms↗
PubMed1981

[Percutaneous transhepatic biliary drainage in obstructive jaundice. Report of 19 cases (author's transl)].

The development of percutaneous transhepatic techniques of access to biliary tree with the fine needle made possible the wide diffusion of percutaneous biliary drainage. Results of 19 attempts of biliary drainage are presented; success rate in positioning external or external-internal drainage was 79% (92.3% in the last year). The technique employed is described and discussed comparing it with the methods proposed by other authors. Early therapeutic effects and long-term benefits on bilirubin levels and survival were good. Only 2 major complications were observed (hepatic abscess and biliary subcapsular cyst) but they did not require surgery. Cholangiocarcinomas and ilar hepatic metastases appeared to be elective indications to definitive palliative drainage, but pre-surgical or palliative drainage is also recommended in all cases of obstructive jaundice. Careful follow-up and check of patients with the biliary drainage improves the drainage function and reduces the complications.

Biliary Tract↗
PubMed1978

[Radiotherapy of oral cancer. Late results (author's transl)].

Radiotherapy of the primary site was employed between 1959 and 1965 in the treatment of 335 unselected cases of mouth cancer. The series is examined with regard to the long-term results and gross survival is evaluated in accordance with an actuarial method. Differences dependent on sex and age, and on the type of cancer involved and the treatment modalities are illustrated and discussed.

Adult↗
PubMed1976

[On 23 cases of postinfartual interventricular septal rupture s].

Twenty-three patients with ventricular spetal rupture complicating acute myocardial infarction underwent surgical repair. In 15 patients the interval between occurrence of myocardial infarction and operation varied from 2 to 18 days and in 8, from 2 to 9 months. In the group of the patients operated on early after the myocardial infraction (less than three weeks) the hospital mortality was 60%; in the group of patients operated on later, the ospital mortality was 12%. Tir six patients had a cardiac catheterization which showed a decrease of the end diastolic left ventricular pressure and a decrease of the pulmonary pressure. In two patients a residual small left-to-right shunt was present. The Aentricular septum is surgical; B) the surgical closure of the rupture should be delayed when possible from three to six w-eks after the infarction; C) in the patients operated on early after the myocardial infarction the operative risk is high, but the long-term results are good, as they are in the patients operated on later after infarction.

Acute Disease↗
PubMed1976

[Congenital coronary fistulas: report of six operated cases (author's transl)].

The authors report of their own experience of 6 patients suffering from congenital coronary fistula. In 3 cases the fistula originated from the right coronary artery and in the other 3, from the branches of the left coronary artery. In 2 cases the fistula ended in the right atrium and in 4 cases in the right ventricle. Three patients were asymptomatic, 2 with cardiac insufficiency and 1 suffering from angor. We normally recommend surgical operation for the symptomatic patients, and for the asymptomatic, whenever there is a considerable shunt sin/dx and/or for important electrocardiogram alteration. All of the patients was operated on, 4 of them by means of extracorporeal circulation. In 3 of them a straight ligation of the fistula was carried out: in one, ligation of the fistula associated with the removal of a myocardial aneurysm, in one the suture of the intima of the fistula after arteriotomy, and in one the suture after right atriotomy. There were no complications immediately after the surgical operation. Five of our patients were checked from 3 to 7 years after the operation. All of them showed a normal radiological picture and disappearance of electrocardiogram evidence of pre-existing myocardial ischemia.

Adult↗
PubMed1976

[Operative and long term results in 52 patients operated on for chronic postinfarction left ventricular aneurysm (author's transl)].

Operative and late post-operative results in 52 patients undergoing operation for chronic postinfarction left ventricular aneurysm are described. Aneurysm resection was performed in 33 patients. This procedure was combined with myocardial revascularization by means of insertion of a venous aorto-coronary by-pass graft in 14 cases. Hospital mortality for the total group was 3,8% (2 deaths). Surviving patients were followed-up 3 to 66 months. Two late deaths occurred. Clinical and functinal improvement occurred in the majority of surviving patients. The impact of simultaneous aorto-coronary by-pass grafting on operative results is discussed.

Adult↗