Biomedical subjects
G Crepin
Publications and source records attributed to G Crepin.
[Preclinical forms of cancer of the uterine cervix in pregnant women].
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Sound stimulation test and fetal well-being.
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[Reaction of the newborn infant less than 2 hours after birth to the maternal voice].
Our group provided in 1981 evidence of a transmission of external voices, particularly the mother's voice, into the pregnant uterus in the human. The present study was carried out in order to investigate the actual perception and memorisation of this particular feature of the fetal environment. 25 infant newborns, 20 within the first hour of life and 5 during the second hour, with no post-natal experience of the mother's voice, were submitted to five females voices. The mother's voice rank was determined by randomization. The stimulus consisted in the first name of the newborn, repeated three times, with no associated visual or tactile perception. The behavior of the newborn was studied on videotapes by three of the investigators, without knowledge of the rank of the mother. Three levels of response were determined: no reaction, weak response (segmental movement) and complete response (orienting movement). The behavioral responses to the mother's voice were significantly different (p less than 0.01). The mother induced 36% of complete responses, when the unknown voices induced only 12% (p less than 0.001). Because the intonation of the mother was found, as expected, significantly warmer, this factor had to be controlled. After exclusion of cold voices, a significant difference persisted (45% of complete responses to the mother versus 16% to the other women, p less than 0.02). A fetal perception of external sounds in demonstrated. Moreover, evidence of a prenatal experience of the mother's voice, possibly involved in the process of attachment, is provided.
[Tetradactyly of both hands, hypoplasia of both fibulas and scapuloiliac hypoplasia: a new syndrome?].
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[Epidemiological aspects of the foetal alcoholism syndrome. 45 cases (author's transl)].
During a prospective study conducted in Roubaix, 45 neonates presenting with the craniofacial malformation characteristic of the foetal alcohol syndrome were identified over a 3-year period. Twelve had signs of severe alcoholic embryo-foetopathy. This condition, which affects one in 700 neonates, occurs in multiparous women (mean age, 33 years) of low socio-economic status suffering from long standing, complicated alcoholism. Although the mean ethanol blood level may be as high as 1.82 g/l, this substance does not seem to be the only teratogenic agent.
[How to manage cytologically suspected cervical cancer].
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[Intra-uterine sound and fetal auditory perception].
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[Working out a system for the parameters of intra-uterine pressure wave forms. A comparative study of spontaneous labour and induced labor (author's transl)].
The tracings of intra-uterine pressure changes that are made during normal labours in primiparous patients, whether the labours were normal or accelerated with oxytocin, were analysed using a semi-automatic time-lag with the help of system of 25 parameters. The classical data of pressures and of time have been made up with a study of the minima and maxima of pressure measurements and the drawing up of new indices to characterise the pressure wave form. A study of the correlations between the different groups of parameters made it possible to make a summary of the information from a smaller number of data which were identical for the two groups of delivery. In particular working out the surfaces dose not seem to give extra information over and above that derived from a simple calculation of the length and intensity of the contractions. A comparative statistical study confirms that in accelerated labour there is a rise in the basal tone, in the maximum pressure and in the frequency of contractions, and shows a minimal scatter of the values obtained which demonstrated that oxytocin has a regulating effect. Using parameters for the shape of contractions, quite independently of the units chosen to measure, has made it possible to design a typical form for the graph for each group of labours.
[Present status of early antenatal diagnosis. Evaluation of the activity of a multidisciplinary team apropos of 219 amniotic punctures].
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[Endometrial biopsy and hysterography prior to IUD insertion (author's transl)].
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[Should hemorrhages of the 1st trimester of pregnancy be treated?].
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[Hepatic cirrhosis and pregnancy. Apropos of 5 cases].
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[Cerclage of the cervix for cervico-isthmic insufficiency in pregnancy (apropos of 120 cases].
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[Changes in carbohydrate and lipid metabolism and biliary function induced by estro-progestagens and during pregnancy].
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[A case of crytophthalmos-syndactylia syndrome].
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[Vibramycine in gynecology-obstetrics].
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[Ondogyne in the treatment of ovarian sterility].
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