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Biomedical subjects

G Crespi

Publications and source records attributed to G Crespi.

At least 37 records · Page 2Linked to original sources
PubMed1991

[Captopril-induced changes in renal flow: evaluation using Doppler echography].

It is well known that angiotensin antagonists cause increase of renal blood flow. We have examined, using duplex Doppler sonography, the changes of renal blood flow velocity induced by oral administration of 50 mg. of Captopril. We examined 19 kidneys in 17 subjects without hypertension. Both peak systolic and diastolic velocities were measured at renal hilum and at arcuate arteries, and the resistive index (RI) was calculated. In conclusion duplex Doppler sonography shows significant increase of blood flow velocities both at the hilum and at the arcuate arteries, without variation of the RI, thus showing that changes affect the whole Doppler wave, both in systole and diastole.

Blood Flow Velocity↗
PubMed1990

[Our experience in the use of mechanical staplers in the execution of step-by-step subtotal gastrectomy].

The Authors describe their reconstruction technique after a "step" gastric resection for peptic or neoplastic pathology. The use of staplers such as TA 30 or GIA for the duodenum is reported. After skeletonizing the lesser curve up to the cardias by sectioning the left gastric artery at its origin and up to the penultimate short vessel on the greater curve, the stomach is resected distally to this two points using a TA90 staplers. So it is possible to remove the greater part of the acid-secreting area in order to avoid ulcers of the anastomosis or of the gastric stump, and also to achieve a complete lymphadenectomy in case of neoplasm. Then a Roux-en-Y gastro-jejunal anastomosis is performed using an EEA28 circular stapler. The jejunal stump is closed with a TA30. Finally, a manual jejuno-jejunal anastomosis is made at least at 50 cm from the previous one. From November 1987 to January 1989, 13 patients were operated: 9 for peptic ulcer and 4 for antrum neoplasms. There were no complications during and after the operations. Mortality was 0%. The patient, usually starts eating on the 6th or 7th day after operation, and is discharged on the 10th day. After 6 months an EGD scopy is required: the 8 performed till now have demonstrated excellent anastomosis and no peptic lesions. Scintigraphic evaluations and pH monitoring are still in course to define the gastric stump acid secretion and the absence of biliary reflux.

Anastomosis, Roux-en-Y↗
PubMed1989

Mixed germ cell tumour of the mediastinum (seminoma, embryonal carcinoma, choriocarcinoma and teratoma). Light and electron microscopic cytology and histological investigation.

A mixed germ cell tumour of the mediastinum was found in a 27-year-old subject. It had four components: seminoma, embryonal carcinoma, choriocarcinoma and teratoma. Material for light microscopy (L.M.) and ultrastructural studies were obtained with computerized tomography (CT) guided fine needle aspiration. Three histotypes were identified with ultrastructural studies while only seminoma was identified with L.M. The slides prepared for L.M. were reexamined in the light of findings with electron microscopy (E.M.) and previously unidentified cellular elements were found to be characteristic of choriocarcinoma and teratoma. Histological examination of surgical and autopsy material confirmed the cytological findings. Because of the singularity of this case, the rarity of this type of neoplasm and the difficulty in arriving at a differential diagnosis from other neoplastic and non neoplastic lesions, only the ultrastructural cytological examination allowed us to identify the mixed nature of the tumour. Such an identification is not always possible with L.M. but it is a determining factor in the prognosis and therapy.

Adult↗
PubMed1980

[Internal abdominal hernias. Presentation of 10 treated cases].

Ten cases of abdominal internal hernia observed at the Niguarda Hospital Emergency Surgery Division, Milan, during the period 1969-1978 are described. Even though it is extremely uncommon, this form must be kept in mind in the course of differential diagnosis when the picture includes: typical and striking symptoms of ileal strangulation, radiographical evidence of marked distension of the ileal loops with hydro-air levels, and a negative history of abdominal surgery.

Adult↗
PubMed1979

[Barium peritonitis: report of four cases (author's transl)].

Prompted by several cases of barium peritonitis of their own observation, the authors review the literature on the subject and outline the more common etiopathogenetic factors involved and gross and histological aspects of the disorders. After describing their own four cases of barium peritonitis, the authors outline some basic principles for the prevention and treatment of this rare complication.

Adult↗
PubMed1979

[Internal abdominal hernia caused by anomaly of the falciform ligament (a case report)].

The authors describe a truly uncommon case of internal abdominal hernia attributable to malformation of the falciform ligament. The patient, a man aged 26, had complained in the past of cramping pain in the epigastric region, usually occurring after meals and sometimes ending with vomiting of ingested food; but all diagnostic methods and procedures had consistently ruled out any extant pathology of the stomach, duodenum, biliary tract, or pancreas. Present hospitalization was justified by a clinical picture suggesting peritonitis from perforated gastric or duodenal ulcer. At operation the authors found a strangulated loop of small intestine following left-to-right migration through a hole in the falciform ligament of the liver. In the authors' interpretation the background cause of the trouble was incomplete development of the falciform ligament, and the immediate cause of the acute episode was abnormal motility and exaggerated peristalsis of the ileum, possibly due to the presence of a diverticulum; the latter two conditions are invoked as a possible explanation for the repeated episodes of abdominal pain in the patient's history.

Adult↗
PubMedDate not supplied

Metastatic nodules of the abdominal wall: US and CT evaluation..

PURPOSE: Metastatic recurrence in the abdominal wall surgical scar is not uncommon. Our aim was to evaluate the role of ultrasonography (US), computed tomography (CT) and percutaneous fine needle aspiration biopsy in the diagnosis of metastatic recurrence along the surgical scar. MATERIALS AND METHODS: We evaluated 17 nodules in the surgical scar, either single (n=9 patients) or multiple (n=2 patients), in 11 patients operated on for known abdominal neoplasm confirmed by histology. The most common primary tumour was colonic carcinoma. All patients had undergone open surgery, and the lesions were detected at routine follow-up or at diagnostic examinations performed for clinical suspicion of recurrence. Ultrasonography (7.5-10/10-13 MHz) and fine needle biopsy were performed in all cases; contrast-enhanced CT was carried out in 10 patients. All lesions underwent histopathological examination. RESULTS: The histological findings showed 16/17 metastatic nodules and one suture granuloma. Lesions had variable size (15-55 mm), roundish shape, ill-defined margins (60% cases) and hypoechoic solid echotexture. All were characterised by marked contrast medium uptake on CT examination. US-guided aspiration biopsy precisely defined the metastatic nature of the nodules in 16/17 cases. In the patient with suture granuloma, both CT and US findings suggested malignancy; however, cytology showed only scant fibrous material. The anterior abdominal wall was the most common site of metastatic disease (14 lesions). CONCLUSIONS: US enables an accurate detection and diagnosis of metastatic nodules along the surgical scar. Fine needle aspiration biopsy represents, in our opinion, the most suitable procedure for providing an accurate diagnosis of this condition.

Abdominal Neoplasms↗