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Biomedical subjects

G D Cook

Publications and source records attributed to G D Cook.

4 recordsLinked to original sources

A three-month follow-up of psychological morbidity after early miscarriage.

The loss of a pregnancy in the first trimester is a common event and recent research has identified high levels of psychological distress amongst women who have miscarried. We believe this study is the first to examine the phenomenon from a longitudinal perspective using standardized measures. A sample of 65 women was rated for anxiety and depression using the Hospital Anxiety and Depression Scale at intervals of one, six and 12 weeks following early miscarriage. The results indicate that a large proportion of the sample had clinically important levels of anxiety (41 per cent) and depression (22 per cent) in the first week following miscarriage, which declined to 32 per cent and 6 per cent respectively by the 12th week. No association was observed between levels of psychological morbidity and a number of social and obstetric variables, the only exception being whether or not the pregnancy had been planned. These results are discussed with reference to the relevant literature. The possible implications for further research and clinical practice are addressed.

Abortion, Spontaneous↗

Effect of compression speed on the tensile strength of tablets of binary mixtures containing aspirin.

Mixtures of aspirin with sodium chloride, sucrose, Starch 1500 or Emcompress have been compressed to two maximum upper punch pressures at two compression speeds. Non-linear relationships between tensile strength and composition, and tablet porosity and composition were found in all cases. Tablets of the individual materials compressed at fast speed showed either little change or a reduction in tensile strength when compared with those compressed at slow speed. For mixtures of aspirin with Starch 1500, tablets compressed at fast speed were weaker and more porous than those compressed at slow speed. However, some mixtures of aspirin with sodium chloride, sucrose or Emcompress gave tablets with greater tensile strength and lower porosity when prepared at fast compression speed compared with tablets prepared at slow speed. This behaviour was attributed to the modification of the consolidation behaviour of the aspirin by the second material.

Aspirin↗

Mutual diffusional interference between adjacent stomata of a leaf.

The mutual diffusional interference between adjacent stomata in laminar flow over a leaf is shown to play a decisive role in determining overall transpiration. The magnitude of this interference varies with the interaction of the vapor diffusional shells forming above each stoma and the air flow over the leaf. The interference decreases with increasing incident radiation and wind velocity. The effect of interference on the stomatal resistance to diffusion plays a major role in the overall variations in transpiration.

Journal Article↗