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Biomedical subjects

G Desai

Publications and source records attributed to G Desai.

29 records · Page 2Linked to original sources

The changing pattern of surgical pathology of the thyroid gland in Zambia.

Review of reports of thyroid tissue sent for histopathology to the Department of Pathology at the University Teaching Hospital, Lusaka (UTH) by one of the five general surgical units at the institution during the period January 1981-December 1990 shows a 20pc decrease in the incidence of colloid goitre and doubling of the incidence of the adenoma and carcinoma when compared to the study done at the Central Hospital, Kitwe in the late sixties. In our study for the general pathology of the thyroid gland female to male ratio is 7.4:1; 1.25:1 when only thyroid cancers are considered. The incidence of papillary carcinoma is substantially lower than in the west. Recently, there has been an increased incidence of thyroid abscesses associated with HIV infection. Knowledge of the local pattern of surgical pathology of an organ is important for planning the operative management more effectively but in many developing countries, such as ours, this information is not readily available. Goitre is common in Zambia and to our knowledge to date there is only one comprehensive report done during the period January 1966, to March 1971. This deals with the Northern and Western regions of the country. This study was undertaken to look into the surgical pathology of the thyroid gland seen at the University Teaching Hospital, Lusaka, which is in the central part of the country.

Adolescent↗

Carcinoma of penis in Zambia: associated problems in management.

Thirty-three case reports of patients with carcinoma of penis were scrutinised at the University Teaching Hospital, Lusaka, Zambia to look into the associated environmental problems causing an unacceptable level of morbidity and mortality. Due to social and personal reasons, late presentation and poor follow-up is common. Improvement in the poor outcome is only possible with change in social attitudes and alleviation of ignorance. Educating traditional healers will help. For the present radiotherapy may be the other option to improve the morbidity and survival rates in this potentially a curable cancer.

Adult↗

Indoor radon exposure and active and passive smoking in relation to the occurrence of lung cancer.

Exposure to indoor radon and radon daughters is currently attracting great interest as a possible cause of lung cancer. This concern is supported by several studies, most of them relatively small in numbers or weak in the assessment of exposure. This study encompasses 177 persons with lung cancer and 677 noncancer referents, all deceased and with 30 years or more of residency in the same house in an area with radon-leaking alum shale deposits in the central part of southern Sweden. Exposure categories based on building material, type of house, and ground conditions were created, but measurements of the indoor radon daughter concentration were also made for 142 cases and 264 referents. Active and passive smoking was ascertained through questionnaires sent to the next-of-kin. Overall, the lung cancer risk was approximately twofold with regard to the categories of assumed radon daughter exposure for the rural sector of the population but not for the same categories of the urban sector, possibly because of less precise exposure assessment and influence from other factors. Occasional and passive smokers, as well as passive smokers alone, had a particularly increased risk of lung cancer in association with the increased exposure categories.

Adult↗

Criminal abortions as seen in the University Teaching Hospital, Lusaka.

Every year a large number of patients who are spontaneously aborting are admitted to the Gynaecological ward of the University Teaching Hospital (Lusaka) at various clinical stages of septic, incomplete, inevitable or threatened abortion. An undetermined number of these patients are induced outside the hospital. Analysis of data revealed that 60% of admissions in the gynaecological admission ward are abortions and a number of them present with features of sepsis. In a 4 year study period there were 15 maternal deaths as a result of septic/criminal abortions. Various methods are used to procure criminal abortions; out of which a case of a patient who used a knitting needle to procure abortion is presented.

Abdomen↗