PubMed Health⌕ Search

Biomedical subjects

G Dolcetta

Publications and source records attributed to G Dolcetta.

6 recordsLinked to original sources
PubMed1983

Considerations on tubal sterility of presumed psychogenic origin.

The Authors evaluate a certain number of patients presenting primary or secondary infertility, in the search of any emotional problem which could be responsible for it. While it is hard to demonstrate the psychological origin in some cases of infertility and to quantify its real incidence, the Authors point out the importance of ruling out any psychological factor at the beginning of the work-up for the infertile couple and particularly while ascertaining the tubal patency through the hysterosalpingography, a diagnostic technique which can be very stressing for women.

Adult↗
PubMedDate not supplied

Adenine nucleotides and some related enzyme activities (adenylate kinase and phosphoglycerate kinase) in normal and abnormal human semen.

Adenine nucleotides (ATP and ADP) and enzyme activities of Adenylate Kinase (AK) and Phosphoglycerate Kinase (PGK) were assayed on semen samples from normal and infertile men. In accordance with the values obtained, samples could be classified into two groups: one group with levels of either adenine nucleotides and enzymes assumed as normal; a second group with high levels of all the parameters. The latter group comprised the samples with low sperm density (less than 40 million/ml). When the samples were subdivided according to sperm motility, the above distinction into two groups appeared less evident. Moreover, comparing biochemical parameters with morphological findings some contrasts were seen. Nevertheless, we suggest comparing both biochemical and morphological data for a more detailed classification of human semen abnormalities.

Adenine Nucleotides↗
PubMedDate not supplied

Effects of clomiphene citrate on cervical mucus: analysis of some influencing factors.

A multicenter study was performed to investigate the effects of a standard dose of clomiphene citrate (100 mg/day from day 5 of the cycle for five days) on the quality of cervical mucus. A total of 82 cervical mucus samples from 60 infertile patients (15 with secondary amenorrhea, 16 with delayed ovulation, 15 with anovulatory cycles, 14 with oligomenorrhea) was examined on the day of maximum follicular diameter. As a control we studied 54 cervical mucus samples from 47 patients with documented tubal sterility or infertile partners, who had spontaneous cycles with normal rhythm. Cervical mucus was unfavorable in 59% of the treatment cycles compared with 11% of the control cycles. Clomiphene citrate's antiestrogenic effect on cervical mucus was found to be related to the length of time between the last drug administration and the day of maximum follicular diameter (delta days), since cervical mucus was favorable in 64% of the cycles with a delta days more than 6 and in only 16% of the cycles with a delta days of 6 or less. Clomiphene citrate thus seems able to decrease cervical mucus quality. This could be one of the causes of the discrepancy between the rates of ovulation and pregnancy reported in patients treated with this drug.

Adult↗