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Biomedical subjects

G Dore

Publications and source records attributed to G Dore.

7 recordsLinked to original sources
PubMed2003

Risk factors leading to Cryptosporidium infection in men who have sex with men.

OBJECTIVES: Cryptosporidiosis is a devastating illness in people with HIV/AIDS yet there have been no analytical epidemiological studies measuring risk factors leading to cryptosporidiosis in men who have sex with men (MSM). The objective of this study was to measure the risk factors for exposure to Cryptosporidium among MSM. METHODS: The study was a case-control design. It recruited MSM who had laboratory confirmed Cryptosporidium infection between 1997 and 2000. Participants answered a questionnaire about potential risk factors leading to exposure to Cryptosporidium. RESULTS: 10 cases and 24 controls were recruited. Men having more than one sexual partner in the past month were more likely to have had Cryptosporidium diarrhoea p=0.034 (OR 6.67, CI (1.15 to 38.60). Insertive anal sex (p=0.059) and attending a sex venue one or more times (p=0.059) also increased the odds of having cryptosporidiosis. CONCLUSION: The study results suggest that sexual behaviour is a significant risk factor for cryptosporidial diarrhoea in MSM. The results will be used to inform risk groups about behaviours that may put them at increased risk of cryptosporidial diarrhoea.

Case-Control Studies↗
PubMed2001

Impact of bipolar affective disorder on family and partners.

BACKGROUND: Successful management of major mental illness in the community relies significantly on an informal or non-professional network of caregivers. The needs and experiences of such caregivers have been little studied with respect to major chronic mood disorders. METHOD: A sample of caregivers (n=41) of RDC bipolar disorder was systematically interviewed to determine how this role affected them. RESULTS: Caregivers reported significant difficulties in their relationships with the patient when s/he was unwell, with considerable impact on their own employment, finances, legal matters, co-parenting and other social relationships. Violence was a particular worry for partner/parent caregivers of both male and female patients when the patient was manic. The caregiver's own mental health appeared unaffected. Despite this, the caregivers appeared emotionally committed to the patients and showed considerable tolerance of problem behaviours, which they rank-ordered for difficulty. Among nonfamily partners, knowledge of the illness before cohabitation was poor. LIMITATION: The sampling does not capture caregivers who have abandoned their role, such as spouses who have divorced the bipolar sufferer. CONCLUSIONS: Management of this illness requires a partnership between mental health professionals and the informal caregivers and the authors suggest that each group needs to understand the difficulties encountered by the other. Although erosion of relationships is a well-known complication of bipolar disorder, findings indicate that treating clinicians can rely on caregivers committed to the welfare of the patient.

Adult↗
PubMed2000

An unbridgeable gap? Comparing the HIV/AIDS epidemics in Australia and sub-Saharan Africa.

OBJECTIVE: To compare the HIV/AIDS epidemics in Australia and sub-Saharan Africa, to outline reasons for differences, and to consider implications for the Asia and Pacific region. METHODS: Comparison of key indicators of the epidemic in Australia, and Africa viewed largely through the experience of the Hlabisa health district, South Africa. RESULTS: To the end of 1997, for all Australia, the estimated cumulative number of HIV infections was approximately 19,000, whereas in Hlabisa 31,000 infections are estimated to have occurred. Compared with the low and declining incidence of HIV in Australia (< 1%), estimated incidence in Hlabisa rose to 10% in 1997. In all, 94% of Australian infections have been amongst men; in Hlabisa equal numbers of males and females are infected. Consequently, whereas 3000 children were perinatally exposed to HIV in Hlabisa in 1998 alone, 160 Australian children have been exposed this way. In Australia, HIV-related disease is characterised by opportunistic infection whereas in Hlabisa tuberculosis and wasting dominate. Surveys among gay men in Sydney and Melbourne indicate > 80% of HIV infected people receive antiretroviral therapy whereas in Hlabisa these drugs are not available. IMPLICATIONS: It seems possible that Asia and the Pacific will experience a similar HIV/AIDS epidemic to that in Africa. Levels of HIV are already high in parts of Asia, and social conditions in parts of the region might be considered ripe for the spread of HIV. As Australia strengthens economic and political ties within the region, so should more be done to help Pacific and Asian neighbours to prevent and respond to the HIV epidemic.

Adolescent↗
PubMed1996

The use of back projection to estimate HIV prevalence among pregnant women in Australia.

A statistical method similar to back projection was used to estimate the number of children infected with HIV perinatally from the number of children with AIDS due to perinatal HIV infection. By 31 December 1994 there were 18 children born in Australia and reported to have AIDS due to perinatal HIV infection. Based on these 18 AIDS cases, it was estimated that to the end of 1994 there were between 35 and 57 children born in Australia and infected with HIV perinatally, with a preferred estimate of 43 children. Assuming that the transmission rate of HIV from infected mothers to their babies was in the range 15 to 35%, it was estimated that the prevalence of HIV infection among women giving birth in Australia had increased from 0.03 per 1000 (range 0.02-0.07 per 1000) in 1983-1985 to 0.09 per 1000 (range 0.05-0.20 per 1000) in 1992-1994. This range for the prevalence of HIV infection among pregnant women in 1992-1994 was consistent with estimates of the prevalence from screening studies, and suggests that the prevalence of HIV infection in pregnant women in Australia remains low.

Acquired Immunodeficiency Syndrome↗
PubMed1991

An analysis of task difficulty using the visually degraded stimulus task.

This article discusses the utility of the Visually Degraded Stimulus Task developed in 1986 by Vokey, Baker, Hayman, and Jacoby. The program provides 30 line drawings than can be presented in complete form prior to receiving incomplete forms of the same or similar drawings. In the incomplete form, a small percentage of a drawing can be added with each touch of the computer space bar. By this means the percentage of drawing required for identification can be obtained. In this article, difficulty levels of incomplete picture identification are provided for each drawing under conditions of no previous viewing (no prime), previous viewing in an alternate form (conceptual prime), and previous viewing of the same drawings (exact prime). Modifications to the microprocessor computer program are provided to increase its usefulness as a means of testing priming effects in visual memory. Program applications are provided for the study of memory and neuropsychology.

Adolescent↗