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Biomedical subjects

G Dotzauer

Publications and source records attributed to G Dotzauer.

At least 19 recordsLinked to original sources
PubMed1980

[Plasma separation with membranes--examinations in man (author's transl)].

Plasma separation was carried out using a new cellullose diacetate hollow-fibre module. The pore size of the membranes used was 0.2 micrometer and the cut-off at approximately 3 million dalton. Five litres of filtrate was separated in 80 min. The protein content of the filtrate was 60% of that in the blood plasma. When plasma and filtrate were compared, there was little difference inthe proportions of the immunoglobulins. At the end of treatment, the immunoglobulin content of the plasma had been reduced to 40% of its initial concentration.

Animals↗
PubMed1980

[Analysis of a boxing match with fatal outcome resulting from unusually severe brain damage (author's transl)].

A boxing match with fatal outcome is described. The boxer received 21 punches in the nape of his neck, as well as many other blows. After a knock out in the 15th round he conceded the fight; some minutes later he suddenly collapsed. Deep unconsciousness, maximal dilated pupils and extensor-spasms were observed but respiration continued. Although it was possible to evacuate a subdural hematoma 30 to 45 min later, a high-grade cerebral oedema remained resistant to therapy. In addition hypoxemia caused disseminated necroses of heart-muscle fibres. Intensive hemorrhages were detected in the cervical muscles and in the dorsal parts of the intervertebral discs on the level of C 2/3 and C 3/4. Neuropathological investigation revealed the typical alterations brought about by craniotomy carried out for a subdural hematoma caused by the tearing off of Vv. cerebralis superiores, as well as extensive contusion hemorrhages. The high-grade cerebral oedema caused congestion and dislocation which led to massive hemorrhages, hypoxemia to unusually extensive hemorrhagical and white necroses of cortex and brain stem ganglions. Special attention is paid to the pathogenesis of these findings. A report on boxing--particularly professional boxing--issued by the Federal Institute of Sport Medicine in Cologne in 1977 is critically analysed.

Adult↗
PubMed1980

[Phospholipids in fatal strangulations (author's transl)].

A comparison of phospholipid content of sera from heart blood and sinus blood from the brain with the rate of haemolysis in the blood samples, with age, sex, degree of arteriosclerosis and cause of death, showed a relationship with the cause of death in spite of wide dispersion of the single values. The remaining factors of the 145 unselected human cadavers, which were not putrefied, seemed to have no influence. Small amounts of haemolysis caused a decrease of phospholipid concentration whereas an extensive haemolysis clearly led to an increase. The results of 46 deaths by hanging confirmed the fundamental studies of Berg (1950, 1952), who demonstrated that an increased secretion of phospholipids during the strangulation process is to be interpreted as a vital phenomenon. Compression of cervical vessels resulted in statistically significant differences between phospholipid concentrations in serum of heart and sinus blood.

Adolescent↗
PubMed1979

[The importance of Simon's symptom in cases of hanging (author's transl)].

Radiological and patho-anatomical investigations of the spines of 32 corpses of persons who had committed suicide by hanging revealed spine damage in 81% of the cases. The cervical spine was damaged in 69%, the lumbar spine in 56% of the cases. The typical damage of the cervical spine is a loosening of the discs at the dorsal side, usually at the level of C 4/5 to C 6/7. In the region of the lumbar spine, bleeding between the (anterior) ventral ligament and the discs is the most frequently observed damage (Simon's sy;mtpom). Simon bleeding is brought about by traction force and is not dependent on the age at death or on any existing degenerative changes of the spine.

Adult↗
PubMed1978

[Death on the operating table (author's transl)].

Inquests following death on the table present the expert with a number of problems: he has to assess not only the causal connection between therapeutic or surgical procedures and death of the patient, but also the part played by anaesthesia in the fatal outcome. A number of cases are reported and an attempt is made to provide some objective guide-lines for the expert.

Adolescent↗
PubMed1976

[The problems of deaths by bolus aspiration ("cafe-coronary") (author's transl)].

Twentyseven fatal cases of suffocation by swallowing a bolus were analysed under different aspects. An attempt is made to interpret the functional disturbances which precede death, the causes for disturbance of swallowing and subsequent fatal reflex effects. The problems of judging the situation by the medical expert is discussed. Finally recommended therapeutic measures are critically evaluated to answer the question whether timely and adequate remedies truly exist.

Acute Disease↗
PubMed1976

Self-mutilations in private-accident-insurance cases.

Self-inflicted injuries can be classified in groups. One group deals with the simulation of illness, another with the occurrence itself and the application of chemical, thermic or mechanical methods. One sector concerns self-mutilation, which, from a psychiatrist's point of view, is interesting. At this time we are more concerned with the problems of proving it. In wartime and even during military service in peace-time soldiers inflict mutilating injuries on themselves. They are motivated by the notion that they will gain benefit from their action. Economic gain plays a role in the case of people who have taken out private accident insurance: self mutilation to simulate the result of an accident. Our investigation into self-mutilation started with an analysis under the following aspects of 123 cases: age, sex, occupation, place of residence, place and time of deed, method employed (weapon used), localisation, single or multiple wound, direction of injury, position of fingers, nature of edges of wound. Whether or not an injury was suffered voluntarily or involuntarily can only be determined with the help of auxiliary facts. It must be clarified whether or not the information given by the injured person ties in with facts concerning the place where the injury was sustained, its position and its direction. The medico-legal expert should not interpret medical findings without relating them to the facts of the case. Indeed, he should start by examining the claimant's account of the accident. To some extent it almost requires the work of a general staff to compare the findings of a careful medical investigation with the injuries themselves. If the injury was inflicted by a certain tool information must be available regarding, for example, the "accident with the saw" together with an assessment of the wounds sustained (utilization of clinical material). Sometimes tests on corpses need to be carried out because these can provide information on mechanical and physical problems. When the direction of the wound is being clarified together with an appraisal of any traces found electron scanning and microscopic tests should also be incorporated into the examination in addition to medical and X-ray tests. At the slightest suspicion that a wound might have been self-inflicted appropriate tests should be carried out immediately. Conclusions should only be drawn by someone who has made an intensive study of this special field which is of such great forensic interest.

Adult↗
PubMed1976

[Differentation and timeinterval for detection of tissue cells on a weapon used in a crime (author's transl)].

There are numerous methods of examining the weapon used in a crime to detect evidence of blood or of blood-group properties. Forensic literature also contains references to the tracing of organic tissue. In the case against Jaccoud the two medical experts called upon, UNDRITZ and HEGG, found evidence of cells from internal organs on a knife which had possibly been used to commit the crime and which had been stored away for some considerable time. Practical experience has shown that the likelihood of finding cells on the weapon used is small; however, it is greater in the case of abdominal injuries than in the case of stab wounds in the chest. Tests carried out on corpses have revealed evidence that cells from the liver can adhere to a blade plunged into the organ. This happens mostly when a knife with a serrated or wavy edge is used. The abdominal wall has a greater cleaning effect on a blade than clothing does. It is of crucial importance to clarify the environmental conditions to which an object bearing certain traces has been exposed. Over a long period of time it is much easier to detect parts of organs if they have been subjected to swift dehydration (by the wind, for example). A location which is either warm or damp and humid makes identification, even after a few hours, no longer possible. The presence of a single tissue cell, especially if it should have managed to retain its structure after several months' dessication, can never suffice for an organic diagnosis. How many determining characteristics then must be traceable? And how great is the certainty of identification with regard to cells from other organs or to nun-human cell structures - all of which are also subject to environmental and time factors? How many single tissue cells must be identified to determine conclusively that the cells in question came, for example from the liver?

Autolysis↗