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Biomedical subjects

G Duport

Publications and source records attributed to G Duport.

9 recordsLinked to original sources
PubMed1979

[Mitral valve prolapse and spasmophilia in children and adolescents].

71 cases of mitral valve prolapse (MVP) in the child and adolescent with an age range of 3 to 20 years were reviewed. The clinical symptoms, electrocardiography and catheter and angiographic data of this mitral abnormality were analysed. A systematic study of the electrocardiogram showed a tendency to spasmophilia in 68% of cases. The serum calcium, phosphate and magnesium levels were normal in 90 to 95% of patients. A reduced erythrocytic magnesium level seems to have been found in some patients. It is interesting to observe the similarity between the clinical signs in MVP and in spasmophilia. These clinical, biochemical and electrocardiographical results justify the systematic investigation of children and adolescents with MVP, with a view to the diagnosis of spasmophilia.

Adolescent↗
PubMed1979

[Mitral valve prolapse and spasmophilia in the adult].

75 cases of mitral valve prolapse (MVP) for which no cause was found underwent electromyography (EMG). In 64 cases (85.3%) EMG showed changes suggestive of spasmophilia. The symptoms observed were those already described in this condition. The specific clinical signs of spasmophilia were often elicited with a positive Chvostek sign in 20 out of 30 cases (73.3%). Radiological, echocardiographical and haemodynamic studies underlined the hyperkinetic state of the left ventricle. Biochemical investigations showed a high incidence of low erythrocytic magnesium levels. Chest pain suggestive of angina pectoris, mitral valve prolapse and spasmophilia are frequently associated. The role of the low erythrocyte magnesium on left ventricular hyperkinesis and the production of MVP is discussed.

Adult↗
PubMed1978

[Crenelation of Beall's prostheses in mitral position: apropos of 21 reoperated cases].

The authors report their experience of 21 revision operations for malfunction of the Beall Surgitool 104 prosthesis used in the mitral position. The incidence and uniformity of the disorders found in the prostheses suggest that these changes are produced inevitably usually during the fourth year. The disc becomes kinked, the mountings eroded, and the teflon ring torn. The clinical features are the onset of heart failure, anaemia, or a thrombo-embolic episode. These three findings may occur individually or in association. The authors do not advise systematic revision surgery, but conclude that close follow-up is essential in the case of all patients who have had a Beall prosthesis. Early signs of failure should be revealed by clinical examination, the level of LDH, and by phonocardiogram and echocardiogram studies. Leaving aside thrombo-embolic episodes and severe anaemia which themselves constitute indications for revision surgery, the decision to replace the damaged prosthesis should be taken as soon as the first signs of cardiac failure are detected.

Anemia, Hemolytic↗
PubMed1977

[The mitral apparatus and surgery of sub-valvular aortic stenosis].

The authors present three eases of subvalvular aortic stenosis caused by an abnormality of the mitral valve mechanism which required placement of a prosthetic valve. They describe the types of mitral valve abnormality which are reported in the literature to have caused obstruction to the aortic outflow tract. They analyse the criteria for diagnosis of this condition, and the surgical treatment. The placement of a prosthetic mitral valve does not always remove the obstruction to the aortic outflow, especially if there is an abnormality in the position of the mitral ring.

Adolescent↗
PubMed1976

[Treatment of rhythm disorders by fenoxedil hydrochloride].

Fenoxedil chlorhydrate (FC), which is used as a treatment for cerebral circulatory failure and peripheral vascular disease, has been given to 100 patients with a cardiac arrhythmia: atrial fibrillation (78 cases), atrial flutter (4 cases), atrial tachysystole (2 cases), ventricular extrasystoles (12 cases), and supraventricular extrasystoles (4 cases). FC has been prescribed alone, or as a complement to current anticoagulant or digitalis treatment; combination with prenylamine, amiodarone, dysopyramide or a drug of the quinidine group must always be avoided, and the potassium level checked and corrected if necessary before treatment. In 78 cases of atrial fibrillation, the authors found that sinus rhythm was restored in 58 (74.4%); four cases of flutter were restored, and one case out of two of atrial tachycardia. In case of supraventricular and ventricular extrasystoles the results are less clear, and merit a further study with a larger number of cases. The electrocardiographic disorders encountered in this series have been evaluated: lenghthening of the QT interval, disorders of atrioventricular conduction, sinus inhibition. They were either produced by or aggravated by the FC. No cases of axis deviation were encountered. The authors make mention of the complications observed by other authors, but draw a distinction between the prescription of FC in cases of cerebral vascular insufficiency, without previous knowledge of the exact cardiac status of the patient (otherwise there is a risk of severe accidents), and the use of FC in cases of arrhythmia which have undergone full assessment before the drug is used. According to this study, FC appears to be a very effective anti-arrhythmic agent, but its use demands very rigorous clinical and electrocardiographic supervision.

Anti-Arrhythmia Agents↗
PubMed1975

[Electrocardiogram after complete repair of tetralogy of Fallot].

207 cases of Fallot's tetralogy having undergone complete surgical correction have been studied in this work as regards the electrocardiographic changes induced by surgery. The observed anomalies were the following: --Intraventricular conduction disturbances --179 cases (86,5%) --Atrio-ventricular block --33 cases (16%) --Arrhythmias --29 cases (14%) --Myocardial infarction patterns --6 cases (2.9%). In the atrioventricular conduction disturbances, right complete bundle-branchblock was most frequently observed (126 cases, 70.4%). In 22 cases, it was combined with left anterior hemiblock, the onset of which seemed to be favoured by the previous existence of a minor left anterior hemiblock. Of the 33 cases of atrio-ventricular block which started during operation or immediately afterwards, 13 will remain permanent, 10 of which were of a high degree, requiring implantation of an intracorporeal pacemaker in 8 cases. No case of block started later on, the cases of delayed block being in fact recurrences of transient blocks which had appeared during or immediately after the operation. The candidates to sudden death by paroxysmal block are therefore patients who had a transient block during of following operation, especially if they had besides bilateral bundle-branch block. The arrhythmias were on the whole devoid of danger. 6 cases of myocardial infarction (2.9%) were observed; their incidence is therefore not negligible.

Arrhythmias, Cardiac↗