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Biomedical subjects

G Duprat

Publications and source records attributed to G Duprat.

14 recordsLinked to original sources
PubMed2000

Orbital compression syndrome after orbital extravasation of X-ray contrast material.

PURPOSE: To report the orbital compression syndrome after orbital extravasation of x-ray contrast material during catheterization of the left middle meningeal artery. METHODS: Case report. RESULTS: A 61-year-old woman had profound loss of vision, pain, and proptosis of her left eye immediately after catheterization of the left middle meningeal artery. Computed tomography (CT) revealed that contrast material had extravasated into the orbit. Her symptoms improved with lateral canthotomy and cantholysis and resolved totally within 24 hours without the need for an orbital surgical procedure to remove the contrast material. CONCLUSION: This report describes an unusual cause of the orbital compression syndrome.

Compartment Syndromes↗
PubMed1989

A new device for transcatheter closure of the patent ductus arteriosus. A feasibility study in dogs.

A new device for transcatheter closure of the patent ductus arteriosus was developed and initially evaluated in the vasculature of adult mongrel dogs. The device consists of a nylon sack that can be made in various sizes and shapes. A small flexible crossbar attached to the distal end maintains the position of the sack while it is filled with a segment of modified guide wire. The device is delivered coaxially through a 10-Fr Teflon catheter and is easily repositioned or retrieved before release. The expansile force of the sack against the vessel wall can be varied, and its stability is easily checked prior to detachment. The device produced immediate and permanent vascular occlusion without inflammation or erosion. Over time, the entire unit became incorporated into the vessel wall by neointimal encasement. Nylon sacks offer a simple, unique method of closing virtually any ductus arteriosus without general anesthesia and major surgery.

Animals↗
PubMed1989

Phentolamine for enhanced visualization of distal arteries in lower extremity arteriography.

To augment visualization of the distal arteries, phentolamine was administered to 83 patients (164 limbs) undergoing lower extremity arteriography. Arterial visualization was graded into three classes and skin temperatures were recorded. Phentolamine provided very good visualization of the distal arterial bed in 95% of limbs. A strong correlation was observed between the temperature rise of the feet and the class of arterial visualization. No side effects were recorded. The use of phentolamine in lower extremity arteriography is recommended.

Angiography↗
PubMed1988

Pyocolon: an unusual manifestation of colon ischemia.

An unusual manifestation of a large bowel ischemia was observed in two patients. Both had a left flank tubular fluid collection demonstrated respectively by computed tomography (CT) and ultrasonography (US). At surgery, pyocolon (i.e. ischemic, dilated large bowel segments filled with pus) was discovered and resected. Pyocolon should be suspected in patients with ischemic colitis and sepsis. US, although useful, may be misleading; CT is the investigation of choice to establish the diagnosis.

Aged↗
PubMed1987

Flexible balloon-expanded stent for small vessels. Work in progress.

A new type of flexible, balloon-expanded, stainless steel stent was designed for introduction into small vessels subject to motion. Four stents placed in four dogs were patent at follow-up (4-8 weeks). A fibrocellular proliferation involving the intima and media was responsible for a 20%-25% luminal narrowing observed in all vessels with stents. The stent has longitudinal flexibility, which should permit its insertion into small peripheral, visceral, and coronary arteries.

Animals↗
PubMed1987

Self-expanding metallic stents for small vessels: an experimental evaluation.

Thirty-three self-expanding metallic stents were placed in 24 arterial segments of the hind legs and nine arteries of the abdominal viscera in seven dogs. Twelve 5-mm stents, eight 4-mm stents, and 13 3-mm stents were inserted. Follow-up ranged from 4 to 30 weeks. All 4-mm and 5-mm stents were patent at follow-up. Seven (54%) of the 3-mm stents remained patent. Stent wires were completely covered by a proliferation of the intima. No stent migration, occlusion of side branches, or vessel wall perforation was observed. A stent/artery ratio (SAR) was computed using stent and recipient vessel diameters. Good vascular patency was observed when the SAR was less than or equal to 1.2. An SAR greater than 1.2 was associated with immediate spasm, immediate or delayed thrombosis, or excessive intimal proliferation. Selection of correct stent size is a major determinant of patency in small arteries.

Angiography↗
PubMed1987

Pulmonary complications of multimodality therapy for esophageal carcinoma.

Thirty patients with cancer of the esophagus were treated with multimodality therapy. We studied the incidence of pulmonary complications in these patients. The value of chest radiographs and sequential measurements of carbon monoxide diffusing capacity (DLco) in predicting pulmonary toxicity was determined. Patients were divided into two groups, according to treatment. Patients in group I (n = 16) received two cycles of chemotherapy (bleomycin 15 units/m2, cisplatinum 120 mg/m2, vincristine 2 mg) and radiotherapy (50 Gy). Based on the presence of interstitial lesions on chest radiographs in five patients the incidence of pulmonary toxicity was 32%. In four of these five patients such an appearance was preceded by a drop in DLco: this was documented in 8 of the 16 patients. Nine patients of group I underwent esophagectomy and four (44%) developed adult respiratory distress syndrome (ARDS). In group II (n = 14) the tumor was resected without other treatment and four (29%) of these patients developed ARDS. The incidence of ARDS in both groups demonstrates that pulmonary complications are mainly related to surgical manipulation and to preexisting lung disease. Preoperative radiotherapy and chemotherapy may be associated factors. Sequential measurements of DLco are more sensitive for detecting pulmonary damage than chest radiographs and should be used to predict pulmonary toxicity.

Bleomycin↗
PubMed1986

Intrarenal epidermoid cyst.

Epidermoid cyst is a very unusual cause of renal mass. Only two cases have been reported in the English or French literature. We have encountered this entity in a 4-year-old Haitian boy investigated for urinary frequency. This diagnosis must be included in the differential of coarse calcified intrarenal masses.

Child, Preschool↗
PubMed1984

Intra-arterial infusion chemotherapy in rectal cancer.

Chemotherapy by intra-arterial infusion, using mitomycin C and 5-fluorouracil, was administered to six patients with cancer of the rectum. In three patients who presented initially with an inoperable rectal tumour, medication was infused through the inferior mesenteric artery. Tumour regression was documented in all three, allowing subsequent resection in two. Of three other patients with locally recurrent rectal cancer, none showed tumour regression after infusion, but two experienced substantial relief of perineal pain, with improvement in the quality of life. Unexpected complications occurred in the form of a reversible ischemic colitis in two patients and an arterioenteric fistula in a third.

Aged↗
PubMed1983

Bowel displacement due to psoas muscle hypertrophy.

Extrinsic compression of the medial border of the ascending colon and bilateral small bowel displacement at the lumbosacral level were observed in a sportswoman. Psoas muscle hypertrophy was confirmed by computed tomography. This entity should be added to the differential diagnosis of bowel displacement.

Adult↗
PubMedDate not supplied

Inferior phrenic artery embolization in the treatment of hepatic neoplasms.

Twenty-nine inferior phrenic artery embolizations were performed in 20 patients with primary or metastatic hepatic neoplasms. All patients had interruption of their hepatic arteries by previous infusion of chemotherapy, hepatic arterial embolization or surgical ligation. In one patient, bilateral pleural effusions developed following embolization of the inferior phrenic artery. No other severe complications occurred. Inferior phrenic artery embolization is a safe procedure and permits the continuation of transcatheter treatment of hepatic neoplasms.

Adult↗