PubMed Health⌕ Search

Biomedical subjects

G E Burch

Publications and source records attributed to G E Burch.

At least 19 recordsLinked to original sources
PubMed1979

Of conformists.

Explore the source record for details and available documents.

Education, Medical↗
PubMed1979

Of solo practice.

Explore the source record for details and available documents.

Professional Practice↗
PubMed1979

Of bloodletting.

Explore the source record for details and available documents.

Bloodletting↗
PubMed1979

Of peer review.

Explore the source record for details and available documents.

Peer Review↗
PubMed1979

Fine structure of digital vascular lesions in Raynaud's phenomenon and disease.

The ultrastructural changes in the vessels of the fingertips of patients with Raynaud's phenomenon or disease, with or without scleroderma, are described for the first time. Fingertip specimens were taken by punch biopsy. The light microscopic changes, including segmental vasculitis, fibrinoid degeneration of capillaries, and involuntary regression of glomus bodies explain the reduced digital blood flow associated with Raynaud's disease and phenomenon. The moment-to-moment digital blood flow, recorded rheoplethysmographically, was low when the patient was in a comfortable environment and was increased in a hot environment. This result substantiates the therapeutic importance of reflex vasodilatation. These findings correlate well with the ultrastructural changes in capillaries, including multiple cytoplasmic folds in endothelial cells, abundant intracytoplasmic filaments, and unusual incorporation of collagen fibrils in the basement membrane. These changes must influence nutritional and thermoregulatory function of the digital blood vessels.

Adolescent↗
PubMed1979

Lesions induced by encephalomyocarditis virus and coxsackievirus B in newborn mice.

Electron microscopic studies of various tissues from virus-infected newborn mice disclosed a consistent form of viral cytonecrotic ultrastructural lesion in divergent types of cells (myocardial, valvular fibroblastic, aortic, exocrine and endocrine pancreatic, and hepatic cells) due to three different picornaviruses (coxsackieviruses B4 and B1 and encephalomyocarditis virus). The lesion is characterized by numerous membrane-vesicle complexes, margination of nuclear chromatin or nuclear pyknosis, dilation of rough endoplasmic reticulum, inflammation, and, at times, mitochondrial swelling. It seems apparent that the finding of this ultrastructural type of cytonecrosis is characteristic of a picornaviral infection regardless of the tissue involved and the offending member of the picornavirus group.

Animals↗