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Biomedical subjects

G E Burgess

Publications and source records attributed to G E Burgess.

11 recordsLinked to original sources

Fetal response to cardiopulmonary bypass.

The fetal heart rate (FHR) was continuously monitored by ultrasonography during a mitral valve replacement in a patient at 22 weeks' gestation. The changes in FHR were analyzed in relationship to events of cardiopulmonary bypass. The baseline FHR dropped substantially during bypass with initial loss of variability. After the pump run, a brief episode of fetal tachycardia was followed by stabilization to preoperative levels. The patient delivered at 30 weeks' gestation and the infant did well.

Adult↗

Endotracheal tube ignition during laser surgery of the larynx.

The ignition of an endotracheal tube was caused by laser penetration of an unprotected portion of the tube during resection of laryngeal papillomas. We discuss the factors that contributed to the ignition, the hazards that were encountered, and the methods of prevention that were used.

Carbon Dioxide↗

Alpha blockade and surgical intervention of pheochromocytoma in pregnancy.

The antepartum diagnosis of pheochromocytoma concurrent with pregnancy has been reported in 42 cases. These cases were analyzed for the effect of preoperative alpha blockade and of the timing of surgical intervention. Alpha blockade, when performed promptly in all pregnant patients in whom the diagnosis of pheochromocytoma was made, reduced fetal mortality regardless of the gestational age. In addition, when the diagnosis of pheochromocytoma was made in the third trimester of pregnancy and alpha blockade was adequately maintained, a combined procedure of cesarean section and tumor resection was best. If the tumor could not be located during a combined procedure, delivery followed by delayed resection was not associated with any greater maternal mortality. The surgical approach required for patients diagnosed in the first or second trimester was less clear. Although alpha blockade is indicated in such early patients, it cannot yet be determined if a delay in the tumor excision will subject the mother and fetus to a greater risk than the accepted practice of early resection with delayed delivery.

Adrenal Gland Neoplasms↗

Continuous monitoring of skin temperature using a liquid-crystal thermometer during anesthesia.

Forehead skin temperature measured by a stip of liquid-crystal material was compared to esophageal, rectal, and axillary temperatures measured by thermistor probes in patients having general anesthesia for coronary artery bypass grafting. Before extracorporeal circulation, forehead skin temperature was lower than axillary, rectal, and esophageal temperatures by approximately 2.2 C (4.0 F). During rapid warming, forehead skin temperature rose concurrently with the other temperatures measured but remained significantly different. The liquid-crystal strip may be useful as a safe, convenient method for routine monitoring of temperature trends during general anesthesia in patients whose exact core temperature need not be continuously monitored. We believe that infants, patients undergoing extracorporeal circulation, major abdominal, vascular, or neurosurgical procedures, or patients with a history of temperature regulatory problem are probably best monitored by a method which more exactly reflects core temperature.

Anesthesia, General↗

Pulmonary embolism with factor XI deficiency.

A patient with factor XI deficiency had pulmonary embolism, although his factor XI assay was less than 1% of normal and his postoperative course was complicated by prolonged bleeding. Programs designed to prevent postoperative venous thrombosis should be carried out in factor XI-deficient patients, since the deficient state offers no protection from a pulmonary embolus. All surgical patients who are to receive low-dose heparin therapy as a part of such a program should be screened by means of preoperative determination of the partial thromboplastin time, to identify previously unsuspected bleeding disorders.

Aged↗

Antacids for obstetric patients.

The aspiration of regurgitated or vomited gastric contents is the most common cause of maternal deaths associated with anesthetics, causing an estimated 2 per cent of all maternal deaths in the United States. The incidence of aspiration is estimated to be one of every 430 patients who undergo cesarean section with general anesthesia. The pulmonary complications of aspiration are improved or avoided if the pH of the gastric contents is higher than 2.50. The oral administration of 30 c.c. of magnesium trisilicate has been shown to increase the pH of the gastric contents to above 2.50 in 100 per cent of treated patients, whereas only 60 per cent of the control group were found to have a pH above 2.50. Oral preoperative or predelivery antacid therapy may help to eliminate the morbidity and deaths secondary to aspiration and as such may be an adjuvant to, but not a substitute for, the safe management of the obstetric patient.

Anesthesia, General↗