Biomedical subjects

G E Gresham

Publications and source records attributed to G E Gresham.

29 records · Page 2Linked to original sources

PubMed1975

Residual disability in survivors of stroke--the Framingham study.

Of 123 survivors of documented completed stroke from the Framingham Cohort, 119 received objective evaluations of functional status along with an equal number of controls matched for age and sex. Of the stroke survivors, 16 per cent were institutionalized, 31 per cent dependent in self-care, and 20 per cent dependent in mobility. In addition, 71 per cent had decreased vocational function, and 62 percent decreased socialization outside the home. Each of these frequencies was significantly greater than the corresponding rate in the control group.

Activities of Daily Living↗

PubMed1975

Osteoarthritis in knees of aged persons. Relationship between roentgenographic and clinical manifestations.

One hundred five (70%) of the knee joints of 75 elderly people showed roentgenographic changes of osteoarthritis (OA); occurrence rates for each of ten clinical manifestations ranged from 7% to 76%. Clinical manifestations were more common in knees with OA by x-ray film than in those without. Crepitus, decreased range of motion, pain, bony enlargement, and instability were simultaneously common in the roentgenographically abnormal knees and significantly less frequent in normal knees. Overall functional disability was verified in 22% of the knees with changes on x-ray film. The findings suggest a more positive and specific pattern of correlation between clinical and roentgenographic findings than has generally been believed. Nevertheless, the frequency of dissociation confirms the importance of making therapeutic decisions according to each patient's individual situation.

Age Factors↗

PubMed1975

The efficacy of antimalarials in systemic lupus erythematosus.

Of 209 patients who fulfilled the A.R.A. criteria for the diagnosis of systemic lupus erythematosus, 43 were selected for study because each had been treated for at least two years with antimalarials, but had not received antimalarials for at least one subsequent year. In each instance, the antimalarial was discontinued solely because of the development of retinopathy. Each year on antimalarials was matched with a subsequent year off antimalarials for each patient. The year immediately following diagnosis and years of pregnancy were excluded. Paired-t test analysis of matched years revealed that general symptoms (fever, fatigue, weight loss) were less common during years on 500 mg chloroquine daily than during years off the drug (p less than 0.05). Skin manifestations were also less frequent during the years on 500 mg chloroquine daily than during the years off (p less than 0.05). No significant steroid sparing effect was found. However, a greater incidence of flare-ups during the matched years off the drug was statistically significant.

Adolescent↗

PubMed1973