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Biomedical subjects

G E Lynn

Publications and source records attributed to G E Lynn.

5 recordsLinked to original sources
PubMed1978

Computerized tomography and auditory-evoked potentials. Use in the diagnosis of olivopontocerebellar degeneration.

The pneumoencephalogram has been the only diagnostic test available to confirm the diagnosis of olivopontocerebellar degeneration during life. This study suggests that pneumoencephalography may be obsolete and that the diagnosis of olivopontocerebellar degeneration may be established by abnormalities seen during computerized tomography (CT) and by abnormal responses to auditory-evoked potentials (AEPs). The combination of CT scans and AEPs provides a completely nontraumatic method of diagnosis in olivopontocerebellar degeneration and eliminates the need for pneumoencephalography.

Adolescent↗
PubMed1977

Auditory evoked brain stem potentials in a case of "locked-in" syndrome.

Auditory evoked brain stem potentials were measured in a patient with occlusion of the basilar artery about 7 mm above its origin, resulting in the "locked-in" syndrome due to infarction at the junction of the lower one third and upper two thirds of the pons. The first three waves of the evoked response originating from the acoustic nerve and auditory nuclei in the caudal pons were normal in wave form, peak latency, and voltage level. Waves IV and V, generated in the region of the lateral lemniscus and inferior colliculus in rostral pons and caudal midbrain, demonstrated prolonged peak latency and reduced voltage, indicative of slowed neural conduction in the pons above the level of the superior olivary complex. These findings suggest that auditory evoked potential recordings may have considerable value in the localization of brain stem disorders.

Acoustic Stimulation↗
PubMed1975

Temporal bone studies: findings with undecalcified sections in a 2,600-year-old Egyptian mummy.

Roentgenologic studies by polytomography of the temporal bones of a 2,600-year-old Egyptian mummy (PUM-II) revealed an increase in radiographic density throughout the left temporal bone. The superior portions of the petrous bones were removed with an electric saw for study by undecalcified techniques. For histological control, a similar specimen was removed from a cadaver immediately after autopsy. Light microscopy of sections showed excellent preservation of the Haversian systems. The vascular channels were clearly seen, and they were similar in appearance to those of the fresh specimen. The lacunae contained osteocytes with good preservation of the nucleus. Osteoid seams were identified and the osteon activity was described for the first time in an Egyptian mummy. There was a low turnover type of bone, but there was no evidence of metabolic bone disease. We postulate that the increased radiological density of the left temporal bone was due to a greater amount of resin infiltration in this bone as compared to the right. It appeared that the resin acted as a fixative preserving the bone cells and related elements.

Cell Nucleus↗