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Biomedical subjects

G Egon

Publications and source records attributed to G Egon.

9 recordsLinked to original sources

[Spasticity. Physical therapy, preventive measures and treatment].

Spasticity is one of the most common motor and tonus disorders during the initial phase with traumatic brain injured patients. The evaluation of spasticity is mainly clinical but it is very important to prevent complications such as limitation of range of motion, pain, decubitus ulcers. The therapeutic options consist in classical indications such as baclofen, dantrolene, tizanidine, benzodiazepine, associated with physiotherapy. Other additive therapeutic options could be discussed: use of toxin botulinum in focal spasticity and intrathecal baclofen infusion in case of severe spasticity (often associated with dysautonomic disorders.).

Anti-Dyskinesia Agents↗

Implantation of anterior sacral root stimulators combined with posterior sacral rhizotomy in spinal injury patients.

Brindley-Finetech sacral anterior root stimulators combined with posterior sacral rhizotomy were implanted in 68 males and 28 females with spinal cord lesions. In 9 patients the electrodes were implanted extradurally in the sacrum, and in 90 patients they were implanted intradurally (3 patients had a second extradural implant after a first intradural implant). Three patients died from causes unrelated to the implant. Of the 93 surviving patients, 83 used their implants for micturition and 82 were fully continent. The mean bladder capacity increased from 206 ml preoperatively to 564 ml after the operation. Three patients had a preoperative vesicorenal reflux that disappeared after surgery. In all, 51 patients used the stimulator for defecation. Erection was possible with electrical stimulation in 46 males and was used for coitus by 17 couples. Secondary deafferentation at the level of the conus was performed four times. Three patients who had a cerebrospinal fluid leak were operated on again. Two implants had to be removed because of infection. Sacral anterior root stimulation combined with sacral deafferentation is a welcome addition to the treatment of neurogenic bladder in spinal cord injury patients.

Adult↗

[Electrostimulation of nerve roots in neurogenic bladder].

Thirty per cent of the patients with spinal injuries present chronical urinary problems. For these, G.S. Brindley's technique represents an important progress. It includes a section of posterior roots to control detrusor hyperexcitability and a stimulation of anterior roots to empty the bladder. The equipment is now perfectly reliable and the technique has been defined. Indications are essentially unstable bladders with incontinence and certain hypoactive bladders. The following results were obtained: continence is obtained in 90% of patients; complete bladder emptying in the majority of cases with very marked reduction of urinary infections; improvement of erection and regularization of intestinal transit. The complications of the surgery are uncommon but serious (CSF leaks, postoperative denervations, sepsis and material failure).

Electric Stimulation Therapy↗

Evolution of bladder contraction in course of time after implantation of a sacral anterior root stimulator.

We reviewed bladder contraction evolution after sacral anterior root stimulator implantation in thirty patients operated on from 1984 to 1991. Two patients underwent a complete denervation with a reinnervation within a maximal time of seventeen months. One patient underwent a lesion, like a neuropraxia with a complete recovery at four months. Five patients have undergone a partial denervation with a recovery of miction by neurostimulation within the time of eighteen months. In three patients, bladder contraction disappeared for various reasons.

Electric Stimulation Therapy↗

Adjuvant drug therapy: a review of 30 cases of sacral anterior root stimulator.

Implantation of a sacral anterior root stimulator in spinal cord injured patients must achieve two main goals to maintain a vesicosphincteral balance: complete bladder voiding and correct continence. During the postoperative period, difficulties may arise or persist with either an incontinence due to an insufficient deafferentation with bladder hyperreflexia or an incomplete voiding because of an insufficient contraction of detrusor and/or too high urethral resistances (vesicosphincteral dyssynergia). A third of our patients required specific therapies after implantation to promote interstimulation continence and complete bladder voiding. Regarding continence, adjuvant therapies are effective for bladder hyperreflexia in connection with a too-partial deafferentation. On the other hand, these therapies have little effect on low bladder compliance. In regard to bladder voiding, nonsurgical treatments are equally effective. These treatments (parasphincteral infiltrations, alpha-blockers) must not be permanent, but allow a reharmonizing between expulsive strengths and urethral resistances. Eighty percent of our patients who required adjuvant therapies have been improved significantly. This confirms the efficiency of adjuvant therapy and speaks for patience.

Chemotherapy, Adjuvant↗

[Electrostimulation of anterior sacral nerve roots in the treatment of central neurogenic bladders. G.S. Brindley's technique. Results of the 40 first French cases].

The results of the first 40 cases who underwent implantation of a sacral anterior root stimulator (G.S. Brindley) in France are reported. One patient die two years after implantation from an unrelated cause. 39 patients are using electrostimulation with a 6 month to 8 year follow-up. 90% have a satisfactory continence and no longer require an incontinence appliance. 82% of the patients have a post-void residue of 0 to 50 cc. Urinary infection rate has dramatically decreased. Bladder capacity and compliance have increased, and urethral closure pressure has decreased according to posterior rhizotomy. Possible side effect of total posterior rhizotomy from S2 to S4 could be stress incontinence.

Adult↗

[Electrostimulation of anterior sacral nerve roots in spinal cord injury patients (evaluation of the 1st 25 cases)].

The authors analyse the first 25 patients with spinal cord injuries treated by G. Brindley's technique based on section of the posterior sacral nerve roots to control detrusor hyperexcitability and electrostimulation of the anterior sacral nerve roots to ensure bladder emptying and to facilitate erection and defecation. The indications for this technique are essentially unstable bladders with incontinence and certain hypoactive bladders. The following results were obtained: Acquisition of continence in 90% of cases. Bladder capacity was always greatly increased. Almost complete bladder emptying in the majority of cases. Very marked reduction in urinary tract infection. Regularization of intestinal transit. The complications of this surgery were uncommon but serious: C.S.F. leaks, Postoperative denervations. Sepsis. Material or cable failure.

Adult↗

[Electrostimulation of the anterior sacral nerve roots. An International Congress--Le Mans--24-25 November 1989].

Electrostimulation of the anterior sacral nerve roots in patients with spinal injuries according to the technique described by G. S. Brindley was the subject of an International conference held in Le Mans on 24th and 25th November, 1989. The equipment is now perfectly reliable and the technique has been well defined. Section of the posterior nerve roots increases bladder capacity and promotes continence. Stimulation of the anterior nerve roots contributes to correct bladder emptying. Two other benefits can be expected: improved defecation and erection. Complications are uncommon, but this technique must be reserved for failures of rehabilitation and uroneuropharmacoloical techniques.

Adult↗