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G Enia

Publications and source records attributed to G Enia.

36 records · Page 2Linked to original sources
PubMed1989

Acute interstitial nephritis associated with uveitis and primary hypoparathyroidism.

In a study of a patient with acute renal failure and uveitis, renal biopsy showed acute interstitial nephritis. Serum calcium and parathyroid hormone concentrations were persistently low during the acute phase and after the resolution of renal failure. Clinical history was negative for intake of drugs capable of inducing acute interstitial nephritis.

Acute Disease↗
PubMed1987

Effect of blood cooling on cuprophan-induced anaphylatoxin generation.

We investigated whether cooling of the extracorporeal blood during hemodialysis could prevent anaphylatoxin generation and leukopenia caused by blood-cuprophan contact. After preliminary in vitro studies confirming the temperature dependence of C5a generation, we carried out hypothermic dialysis on nine patients by manipulating blood and dialysate temperature in such a way that blood temperature within the dialyzer averaged 25 degrees C. In comparison with the control procedure (blood temperature within the dialyzer 35 degrees C) hypothermic dialysis reduced peak C5a generation from 41.7 +/- 17 ng/ml to 9.7 +/- 3.4 ng/ml (P less than 0.01), and white blood cell fall from 72 +/- 15 to 25 +/- 20% (P less than 0.01). Arterial PO2 decreased less in hypothermic dialysis (-19 +/- 9% of pre-HD value) than in the control procedure (-30 +/- 11%) (P less than 0.05). We conclude that blood cooling attenuates cuprophan-induced anaphylatoxin generation and leukopenia.

Adult↗
PubMed1987

Severe hypothyroidism induced by amiodarone in a dialysis patient.

A 54-year-old man on regular haemodialysis developed severe amiodarone-induced hypothyroidism after an unusually short latency period. The iodide accumulation and/or the derangement in thyroid function associated with chronic renal failure may predispose uraemic patients to this serious side effect of amiodarone. Although the pharmacokinetics of amiodarone are not altered by renal failure, caution is advised in prescribing this drug to uraemic patients.

Amiodarone↗
PubMed1985

Hyperchloraemia: a non-specific finding in chronic renal failure.

To determine the prevalence of hyperchloraemia (plasma chloride concentration of 107 mmol/l or above) in chronic renal failure (CRF), we retrospectively analysed the acid-base and electrolyte status of 102 Italian and 53 English patients with impaired renal function. Hyperchloraemia was a frequent finding at all stages of CRF with a prevalence ranging from 30 to 50%. It was common both in tubulointerstitial nephropathies (45%) and chronic glomerulonephritis (39%). Hyperchloraemic patients were more acidotic than the normochloraemic.

Acid-Base Equilibrium↗
PubMed1985

The effect of dialysate temperature on haemodialysis leucopenia.

We assessed the influence of dialysate temperature on intra-dialytic leucopenia. Lowering dialysate temperature from 38 degrees C to 20.5 degrees C caused a decrease in the dialysis associated white blood cell reduction from 82 +/- 6 per cent to 32 +/- 19 per cent. The degree of leucopenia bore a highly significant relationship with dialyser blood temperature suggesting that a further lowering of blood temperature (to about 20 degrees C) would almost entirely prevent intra-dialytic leucopenia.

Adult↗
PubMed1981

Light-chain nephropathy in patient with renal carcinoma.

Paraneoplastic syndromes are often associated with renal parenchymal tumours. This report describes a case of renal-cell carcinoma with kappa-chain nephropathy. The patient, a 60-year-old man, had renal tubular dysfunction, shown by low serum concentrations of urate and phosphate. Kappa-chains were found in both serum and urine, but no lambda-chains were found. Investigations showed a clear-cell carcinoma, and the patient underwent a radical nephrectomy. Two years after operation serum phosphate and urate concentrations had returned to normal, and kappa-chains were undetectable in serum or urine. The absence of lambda-chains indicates that the light-chain proteinuria was due to overproduction of the M component, and the disappearance of kappa-chains after the operation suggests a causal relation between the renal tumour and the overproduction of the M component.

Adenocarcinoma↗
PubMedDate not supplied

Diabetes and renal failure: a southern Italian perspective.

The authors carried out a retrospective survey assessing the total proportion of diabetic patients and relative proportion of patients with Type I and Type II diabetes among patients receiving renal replacement therapy and those evaluated for chronic renal failure in a southern Italian renal unit during the period 1972-1986. The proportion of diabetics among patients accepted for renal replacement therapy was 10% (34/336); of the 34 diabetic patients, only one was clearly affected by Type I diabetes, 26 had Type II diabetes, and the classification was uncertain in four patients. Similar relative proportions of Types I and II diabetes were observed among patients referred during the same period for evaluation of chronic renal failure.

Age Factors↗
PubMedDate not supplied

[Oscillometric wrist devices: comparison with the standard mercury sphygmomanometer and estimate of the "supine" error].

Before introducing a wrist device (NAIS-Matsushita) for blood pressure (BP) measurement in our Unit, we formally tested its validity. Since the wrist position is critical and BP in the clinical setting is often measured with patients lying in bed, we also estimated the error introduced by allowing the wrist to lay flat at the bed level. Ten normal subjects and 20 hypertensive patients took part in two consecutive studies. In the first study the subjects were sitting and the blood pressure was simultaneously taken with the auscultatory mercury sphygmomanometer on the left arm and with the NAIS on the right wrist. The wrist was kept at the heart level. In the second study two NAIS devices were used with the subjects lying in bed; the left wrist was allowed to stay at the bed level, while the right one was kept at the heart level. The diastolic BP was consistently underestimated (P< 0.001) by the wrist device (79 mmHg 95%CI: 75-83) as compared to the values obtained with the standard mercury sphygmomanometer (85 CI: 79-88). No significant difference was found in systolic BP (mercury: 135 CI: 127-143; wrist 134 CI: 126-141). In the second study the BP (systolic and diastolic) was markedly higher (P<0.001) when the wrist was kept at the bed level (systolic bed level: 144 CI: 135-152; systolic heart level: 135 CI:126-141; diastolic bed level: 83 CI:78-88; diastolic heart level: 76 CI:71-79).

Adult↗
PubMedDate not supplied

[From CANUSA to ADEMEX: do we need a new paradigm for definition of peritoneal dialysis adequacy?].

Peritoneal dialysis doses were prescribed out of empirical criteria up to the mid-Ninety Then, the observational CANUSA study and the experimental ADEMEX study helped to define adequacy criteria according to urea kinetics model. This review analyzes the limits of a definition of adequacy grounded exclusively on urea kinetics, as well as the need for new parameters of adequacy. The evidence is presented fostering the hypothesis that the control of extra-cellular fluid excess and of other cardiovascular risk factors may now be considered a new target for adequacy.

Cardiovascular Diseases↗
PubMedDate not supplied

[Prevalence of insulin-dependent and non-insulin-dependent diabetes among Italian patients on replacement therapy. Preliminary survey at 3 dialysis centers].

We carried out a retrospective survey to assess prevalence and type of diabetes in three Italian Renal Units located respectively in the North (Tradate, Varese), in the Middle (Latina) and in the South (Reggio Calabria) of Italy. The prevalence of diabetes among patients accepted for RRT was 10.5% (60/659). 40 patients (66.7%) were non-insulin dependent and only 6 patients were insulin-dependent. A similar pattern was observed among the 289 patients referred to the Renal Unit of Reggio Calabria during 1972-1987 for evaluation of Chronic Renal Failure. Our data suggest that among the Italian diabetic patients treated by dialysis and transplantation insulin-dependent diabetes is uncommon. This finding could be explained by the low incidence of insulin-dependent diabetes in Italy.

Adult↗