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Biomedical subjects

G Epstein

Publications and source records attributed to G Epstein.

12 recordsLinked to original sources
PubMed1987

Autologous fibrin tissue adhesive for peripheral nerve anastomosis.

The sciatic nerve in rabbits was exposed, transected, and repaired using either of two methods. The experimental group had an autologous fibrin-based adhesive repair. The control group had conventional perineural suturing. The autologous tissue glue is similar in composition, handling, and performance to the commercially available European product Tisseel. It can be prepared quickly without sophisticated equipment or expense. Autologous glue obviates the risk of transmissible disease that has precluded approval of the commercial product for use in the United States. The glued anastomosis can be performed with accurate apposition and minimal trauma to the nerve. By making a fibrin cocoon, the anastomosis can be insulated. This provides some of the benefits of sheathed anastomosis while minimizing foreign body reaction. Functional evaluation and histologic results comparing the amount of anastomotic fibrosis, axonal regeneration, and alignment of fascicles showed glue to be as good as, if not superior to, conventional suture technique.

Animals↗
PubMed1981

Acquired blepharoptosis secondary to contact-lens wear.

Five patients (eight eyelids) had acquired blepharoptosis after using contact lenses. The ages (26 to 55 years) of these patients was not consistent with idiopathic senile blepharoptosis, and we excluded all other possible causes. All patients had disinsertion and recession of the aponeurosis of the levator palpebrae superioris muscle, and the blepharoptosis improved in each case after reattachment of the aponeurosis to the superior tarsal border. We believe there is a cause-and-effect relationship between the use of contact lenses and the acquisition of secondary blepharoptosis. The most likely explanation of this type of blepharoptosis is difficulty in inserting and removing the lenses. Thus, excessive eyelid manipulation may disinsert the aponeurosis of the levator palpebrae superioris muscle from the tarsus.

Adult↗
PubMed1981

Combined Jones tube-canalicular intubation and conjunctiva dacryocystorhinostomy.

Six patients underwent combined Jones tube-canalicular intubation and conjunctival dacryocystorhinostomy. These patients had epiphora secondary to partial obstruction of the upper and lower canaliculi, complete obstruction of the common canaliculus or a single canaliculus, or paresis of the orbicularis oculi muscle. In these patients we would have performed a dacryocystorhinostomy with silicone elastic intubation, risking recurrent obstruction, or a conjunctival dacryocystorhinostomy with placement of a Jones tube, risking failure of the procedure and complete obstruction of patent canaliculi by placement of the tube. The combined Jones tube-canalicular silicone elastic intubation and conjunctival dacryocystorhinostomy ensured successful treatment of epiphora for this group of patients. Intubating the canaliculi with Bowman probes during placement of the Jones tube avoids injury and subsequent postoperative canalicular obstruction. After several months, the silicone elastic tubing is removed and the Jones tube is plugged. If the patient is asymptomatic and the canaliculi are patent and can be irrigated freely to the nasal cavity, the Jones tube can be removed. However, if epiphora occurs, the plug can be removed and the tube left in place to drain the tears without additional surgery.

Adult↗
PubMed1980

Vascular tufts in retrolental fibroplasia.

Three cases of retrolental fibroplasia with vascular tufts at different locations are described. They probably represent mesenchymal proliferation in response to severe hypoxia. The tufts are reddish-pink in color and angiographically do not leak fluorescein. When present posterior to the equator they suggest an immature retinal circulation and the visual prognosis is poor.

Adolescent↗
PubMed1978

Culture, personality, and behavior: a field study in Jerusalem.

In the setting of Jerusalem's Eastern-Jewish immigrant communities, the author tests the hypothesis that non-Western societies have a theory of disease causation which is at variance with a Western model. What emerges from participant observation, informal interviews, and a formal questionnaire supports the hypothesis, reveals changing attitudes over time, and identifies a category of disease-causation which merits further investigation. These observations may be valuable in the identification of epidemiological aspects of disturbed behavior associated with supernatural beliefs.

Africa, Northern↗