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Biomedical subjects

G Evola

Publications and source records attributed to G Evola.

6 recordsLinked to original sources

[Fetal malformations diagnosed using ultrasonography during tri-test. A retrospective study of 1633 fetuses].

BACKGROUND: To find out which fetal malformations are diagnosed during the tri-test. METHODS: A total of 1633 pregnant women were enrolled in the study and underwent biochemical screening for Down s syndrome and DTN at the Outpatient Clinic for Prenatal Diagnosis of Santo Bambino Hospital in Catania between January 1997 and December 1998. Scans were performed using a TA route in all cases and mainly during the 16th week. RESULTS: 21 abnormal fetuses were diagnosed, equal to 1 out of 77 fetuses (3 cases of isolated DTN; 1 case of cyst in the posterior cranial fossa associated with complex heart malformation; 6 cases of cyst of the choroid plexus; 2 cases of bone dysplasia; 2 cases of cardiopathy; 4 cases of non-immunological fetal hydrops; 1 case of hygroma). In 8 out of 21 abnormal fetuses the tri-test was positive for DNT and SD or atypical. One case of trisomy 18 and 1 case of mosaicism were diagnosed. CONCLUSIONS: A fetal abnormality was diagnosed in one out of 77 fetuses. This finding, although it underestimates the real frequency of these anomalies (retrospective study, selected sample, non optimal period for the diagnosis of fetal malformations, non-systematic study of 4 chambers), once again underlines the importance of a careful morphological evaluation in eyery scan carried out. In our study some malformations were not diagnosed previously because this was the first scan (1 case of anencephaly), or because the abnormality was presumably not present in earlier tests (bone dysplasia at early stage of pregnancy) or because the earlier test was inadequate (2 DTN tested after the 12th week). In some cases it is also possible to diagnose images, such as transient hygromas which indicate a group of patients with a risk of chromosome pathology. Since they are transient, these lesions are only found if the test is performed at a period of pregnancy before the optimal moment for the tri-test. In personal experience the execution of biochemical screening for Down s syndrome and DTN should always be associated with a scan not only to date the pregnancy, but also because it is not infrequent to diagnose malformations.

Adolescent↗

[The hemorrhagic complication of peptic ulcer].

The hemorrhagic complication of peptic ulcer is a pathology which is still responsible for a high mortality. After reviewing the etiopathogenesis and physiopathology of hemorrhagic complications in the light of the recent discoveries regarding H. pylori, the authors report their experience and confirm the important role of surgery in the treatment of this pathology. Resolution is improved by the use of surgical staplers which are regarded as particularly valuable in emergency surgery where the need to cut operating times has undoubted advantages in terms of patient survival.

Adult↗

[Mirizzi syndrome].

Mirizzi's syndrome is a rare, but well described cause of obstructive jaundice which occurs in less than 1% of patients presenting for cholecystectomy. The syndrome is due to a stone impacted in the cystic duct or in the neck of gallbladder, causing compression or obstruction of the common emphatic duct. The clinic, physiopathologic, diagnostic and therapeutic aspects of this disease are described. The patient observed, arrived in emergency with obstructive jaundice and hyperpyrexia. Echography showed a remarkable dilatation of the biliary ducts, whereas endoscopic retrograde cholangiography (ERCP) showed an obstruction of the hepatic common duct of undefinable nature (stone, neoplasia). The surgical operation performed in emergency made clear the diagnostic doubt. Since inflammation impacted biliary duct and gallbladder, an incision of the gallbladder at its fundus was performed. In this way it was possible to extract about 40 stones of dimensions less than 1 cm, and one of 3 x 1 cm, impacted in the cystic duct, compressing the common hepatic duct. A partial cholecystectomy was performed and no connection between gallbladder and common emphatic duct (fistula) was found. The surgical operation led to complete resolution of the symptomatology. Therefore, the conclusions is drawn that Mirizzi's syndrome a rare but non infrequent pathology, finds its definition and complete resolution with surgical operation. Mirizzi's syndrome or obstructive jaundice due to extrinsic compression of principal biliary duct by a stone impacted in the cystic duct, is an uncommon complication of cholecystic lithiasis. Although this syndrome is rare (1%), it causes obstructive jaundice, sometimes dangerous, and serious complications as recurrent cholangitis.

Aged↗

[Treatment of serious hepatic lacerations with Ton That Tung's technique].

BACKGROUND: Serious hepatic lacerations are associated with an elevated mortality which depends on the consequent haemorrhage. The hepatic resection in emergency, according to Ton That Tung, seems to be the more appropriate operation for the rapidity of execution and the low mortality associated (11% out of 1000 operations). METHOD: According to Ton That Tung' technique, 12 operations of hepatic lobe and segment resections were executed after trauma caused by road accidents, firearm lesions, sidearm lesions and bleeding neoplasms. RESULTS: Among 12 patients operated on, 9 healed (75%) and 3 died (25%). CONCLUSIONS: The high mortality in the hepatic resections depends on the technique used. The anatomic resection, according to Bismuth, has an operative time longer than the time described by Ton That Tung, time that in emergency is important because the mortality depends not only from the blood lost, but, also the time in which the blood is lost. Hepatic resection according to Ton That Tung is the gold standard for the treatment of serious lacerations and hepatic bleeding neoplasms.

Accidents, Traffic↗