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G F ODLAND

Publications and source records attributed to G F ODLAND.

7 recordsLinked to original sources

The fine structure of the interrelationship of cells in the human epidermis.

In the present investigation an analysis has been made of the fine structure of the interrelationships of cells in human forearm epidermis by means of the electron microscope. The "intercellular bridges," here called attachment zones, are more complex than has previously been recognized. It is shown that dense oval thickenings, called attachment plaques, appear in apposed areas of adjacent epidermal cell membranes. The tonofibrils terminate at the internal face of the attachment plaque and do not traverse the 300 A distance between apposed plaques. Seven intervening layers of unidentified substance occupy the space between attachment plaques. The attachment zones appear in all of the classical histological layers of the epidermis. The portions of epidermal cell membrane not involved in intercellular attachments have extensive surface area resulting from plication of the membrane, and its further modification to form microvilli. The possible functional significance of these observations is discussed. Prior observations concerning the basement membrane of epidermis are confirmed. Identification of epidermal melanocytes is achieved, the finer morphology of their dendritic processes is described, and their relationship to epidermal cells is discussed.

Basement Membrane↗

Investigation of the structure of the cornified epithelium of the human skin.

To explore the submicroscopic structure of the human callus by the polarization optical method, serial sections were prepared in three principal planes and the sign of double refraction as well as optic axes of various regions of the sections was determined. It was concluded that in areas under the grooves keratin is oriented parallel to the surface plane of the callus and to the direction of the grooves. In component structures of ridge areas such as in sweat duct areas a circumferential, in cross-band areas a linear, and in other parts a random structure was seen. The cross-bands of ridge areas in association with groove areas revealed a regular lattice-like submicroscopic pattern which was considered as an important mechanical system of the cornified epithelium.

Epithelium↗