Massive hemorrhagic hepatic graft necrosis secondary to diversion of portal blood flow during a rejection reaction: report of a case.
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Biomedical subjects
Publications and source records attributed to G F Rondinara.
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The mortality, morbidity and long-term survival in stapled anterior resection for rectal carcinoma has been analysed in 74 patients. Twelve patients were Dukes' A, 26 B, 29 C, and 7 'D' (submitted to hepatic resection). Operative mortality rate was 3 per cent. Three patients (4 per cent) had clinical anastomotic leakage. Two patients (3 per cent) developed anastomotic stenosis. Local recurrence was present in three patients (4 per cent). The mean (+/- s.e.m.) overall survival rate at 5 years was 67 +/- 6 per cent. There was no significant difference in survival between Dukes' B and C (70 +/- 10 per cent versus 59 +/- 10 per cent, P = 0.209). Patients with absent local spread had a significantly better 5-year survival rate than those with positive local lymph nodes (80 +/- 7 per cent versus 54 +/- 9 per cent, P less than 0.01). The present results confirm the satisfactory use of the EEA stapler device for colorectal anastomoses in rectal cancer and in patients with resectable liver metastasis.
ATN is a deleterious problem in the outcome of kidney transplantation. This complication is usually related to multiple factors including donor parameters, surgical technique, ischemic time, and recipient variables. In order to develop prophylactic measures, out of 430 kidney transplants performed in our Department, a series of 90 consecutive cadaveric renal allografts has been considered in this study. The overall incidence of IGNF was 23/90 (25.5%). Kidneys from MOD revealed a lower rate of IGNF (7/35 = 20%) when compared with organs from SOD (16/55 = 29%, P = NS). No difference was noted when kidneys were removed together with heart and/or liver and/or pancreas. Out of the donor factors, only CID was significant (17 +/- 9 hours in IGNF v 11 +/- 10 hours in patients with IGF, P = less than .05). Analysis of data concerning the fate of paired kidneys revealed two cases of IGNF in both kidneys from the same donor v 14 cases of IGNF in only one of the two paired grafts (P = NS). We conclude that: 1. Donor factors are clearly associated with a minority of IGNF. 2. The introduction of multiorgan procurement programs does not complicate early function. 3. Recipient factors (immunological events and intraoperative fluid management) provides important additive effects on initial graft nonfunction.
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Pericystectomy is an excellent surgical procedure for the treatment of hepatic hydatidosis. However, until now, it was not a widely accepted procedure among surgeons because of the lack of literature regarding the details of the surgical technique. During the past years, hepatic hydatidosis has been treated by a majority of surgeons by marsupialization. Only recently, more surgeons have stopped using external drainage procedures in favor of hepatic resection and pericystectomy. In a previous study, we defined some of the criteria for resection of the liver and treatment of hepatic hydatidosis, analyzing the risks and benefits for this procedure. In the present study, we have defined the indications for pericystectomy and discussed the advantages and disadvantages. In a group of 31 patients, a total of 49 cysts were removed by pericystectomy. Some of the major problems related to surgical technique are described and discussed in detail with particular reference to the use of the Pringle maneuver. Clamping of the hepatic ileum, that in our experience never exceeded 20 minutes, has allowed good results--most of all in terms of decreased intraoperative bleeding, postoperative complications and operating time.
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