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Biomedical subjects

G Fabian

Publications and source records attributed to G Fabian.

At least 19 recordsLinked to original sources
PubMed1992

Refraction changes in children developing convergent or divergent strabismus.

Strabismus and amblyopia were studied in a cohort of children born in 1979 or 1980 in the area of Västerås, Sweden. Forty percent of the children had participated in a voluntary eye examination at 1 year of age. All children diagnosed as strabismic and/or amblyopic between 1979 and 1988 at any of the three eye clinics in the area were included in this study. Strabismic cases were mostly detected by the parents while microstrabismus and straight eye amblyopia were found at the general 4 years of age screening at children's health centres. In 57 cases with (n = 31) and without amblyopia (n = 41) it was possible to obtain several refraction values between 1 and 6 years of age. In this study we concentrated on manifest esotropia and exotropia. The aim of the study was to describe changes of refraction before and after onset of strabismus and to establish risk indicators that identified populations at risk of developing strabismus. We found that patients with esotropia show a more pronounced hypermetropia than exotropic cases at the time of detection of strabismus. This difference becomes more definite over time, since hypermetropia increased in the deviating eye in the esotropic cases while refractive errors remained stationary in most of the exotropic eyes. It was also apparent that anisometropia frequently developed after onset of strabismus in esotropic cases in contrast to exotropic cases. An increasing refractive error in the deviating esotropic eye could be combined with an emmetropisation of the fixating eye.

Anisometropia↗
PubMed1990

A longitudinal study of a population based sample of astigmatic children. I. Refraction and amblyopia.

The refraction changes in 310 children with astigmatism greater than or equal to 1.0 D in at least one eye at one year of age were followed during a period of 3 years. At the age 4 years amblyopia was found in 23 children (7%). The refraction data of these children were compared to the rest of the sample. We found that an increasing astigmatism during the test period was associated with an increased risk to develop amblyopia. The majority of children (n = 280) showed a decrease of their astigmatism, whereas all cases with a marked amblyopia (V.A. less than 0.5) or binocular amblyopia, except one, had an increasing or unchanged astigmatism during the age period 1 to 4 years. Strabismus and oblique astigmatism at any time during the test period was also strongly related to amblyopia. The incidence of strabismus (1%) was unexpectedly low. The study also showed that independent of age there was no simple relationship between amblyopia and refraction errors measured at a single test session. The main conclusion of this study is that failure of emmetropization may play an important role in visual development.

Amblyopia↗
PubMed1990

A longitudinal study of a population based sample of astigmatic children. II. The changeability of anisometropia.

The variability of anisometropi in a sample of 310 children with astigmatism at the age of 1 year was longitudinally studied during a 3-year period between 1 and 4 years of age. The prevalence of anisometropia of 1 D or more at each year level was rather stable. When individual cases were examined we found that between the first and the last test session 19 of the 33 children with anisometropia at the first test session had become non-anisometropic and were substituted with 14 new cases which were non-anisometropic at the age of 1 year. In general, less than half of the cases, at all levels of anisometropia, remained anisometropic throughout the whole test period. We also found that children with anisometropia persisting through the whole test period were at considerable risk, about one out of four, of developing amblyopia. There was no simple relationship, however, between anisometropia at a certain age level between 1 and 4 years and amblyopia and/or strabismus. Non-persisting anisometropia in an emmetropizing eye is in most cases a benign sign and not connected with an increased risk for developing amblyopia.

Aging↗
PubMed1989

[Lymph mobilization].

Following a review of the literature lymph mobilization is described. Function and causalities of lymph mobilization and their interactions are explained giving examples and an evaluation of the experience available up to date. In many cases, manual neurotherapy may result in coordination and normalization of disorders which do not respond to other forms of therapy.

Animals↗
PubMed1988

Changes in astigmatism between the ages of 1 and 4 years: a longitudinal study.

Changes in astigmatism during development were studied in 299 infants with astigmatism as they grew from 1 to 4 years of age. All consecutive cases of 1-year-old infants with an astigmatism of 1.0 D or more in at least one eye found at an ophthalmic screening survey were selected for follow-up. The cycloplegic refraction was longitudinally followed at yearly intervals. During development there was no decrease in the degree of hypermetropia, but there was a significant decrease in the incidence and amount of astigmatism during the test period. The most pronounced decrease in magnitude and incidence of astigmatism occurred between the first and second year of life. The majority of astigmatic eyes of the 1-year-old infants had a horizontal curvature greater than the vertical (plus cylinder axis of 180 degrees), and no changes of the axis of the astigmatism were noted during the following years.

Aging↗
PubMed1988

[Cyclic changes in lymph vessels in the pig uterus. Studies of the endometrium].

By means of the orthograde application of Patent Blue Violet and Japanese ink, it was possible to demonstrate the cyclical changes in the uterine lymphatics of the pig. It was found that the lymphatic vessels in the endometrium were markedly dilated during oestrus. In the following phases of the cycle the lymphatics showed a reticulate pattern, which in the stage of preoestrus resembles that seen in oestrus. The transport of the dye into the lymphatics takes place extremely rapidly through the wall of the uterus and then into the mesometrium (serosa), where the lymphatics have a typically beaded appearance.

Animals↗
PubMed1987

[The lymphatic system--terra incognita? Demonstrated by morphological assessment of resorption processes].

The lymphatic system has been demonstrated by means of special microscopic investigations, using morphologically comprehensive resorption procedures. References has been made to the literature which gives an account of the available knowledge about the lymphatic system and the scientific concepts produced in the course of the centuries. After going into the fundamental morphological principles of parenteral resorption and resorption in the bovine uterus, a description is given of the transport of the vital dyes patent blue violet and Japanese ink, which was followed microscopically in the lymphatic system. A further phenomenon emerges with the concept of persorption, where the particles are in the micron range and have also been identified microscopically in the pathways of the lymphatic system.

Animals↗
PubMed1986

Photorefraction: a useful tool to detect small angle strabismus.

Forty patients with small angle strabismus and 30 straight eyed controls were examined by photorefraction in order to establish the validity of this method to detect strabismus. The sensitivity of the method was based on detection of asymmetry of the corneal light and/or fundus reflexes. All cases with a deviation of 2 degrees or more were detected, and 2 controls were falsely considered to be strabismic patients. The sensitivity of the method decreased when the patient wore optimal correction. Photorefraction therefore is considered to be a reliable, simple, and cheap tool with high sensitivity and specificity in screening for strabismus as well as refractive errors.

Adolescent↗
PubMed1986

[The lens of the eye and its relation to the lymphatic system].

On the basis of well-tried methods of investigation with vital dyes (patent blue violet and Japanese ink) and in combination with the drug (Conjunctisan A), the natural pathways of resorption through the lymphatics of the eye in the mouse, were displayed and this permitted the transport mechanisms to be followed. It was possible gradually to understand the morphology of the lymphatic drainage and, in this way evidence was produced regarding the relationships of the lymphatic system and the regional lymph nodes.

Animals↗
PubMed1983

Photorefraction: A useful tool to detect refraction errors.

A simple photorefraction method using simultaneous photography of corneal and fundus reflexes have been used to screen 239 children aged 10 to 15 months for significant refraction errors. The photorefraction results were calibrated to those of cycloplegic retinoscopy. A good agreement was found between the 2 sets of values. The frequency distribution of refraction errors were similar to those presented by Ingram (1979). The aim to detect hyperopia greater than or equal to +2 or myopia greater than or equal to -4 diopters together with significant anisometropia or astigmatism was fulfilled with high reliability. Low degrees of hyperopia, myopia and astigmatism might be missed. Photorefraction therefore is considered to be a reliable, simple and cheap tool with high sensitivity and specificity in screening small children for significant refraction errors.

Astigmatism↗