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Biomedical subjects

G Fasoli

Publications and source records attributed to G Fasoli.

At least 91 records · Page 5Linked to original sources

M-mode contrast echocardiography in patients with univentricular heart.

M-mode echocardiographic peripheral venous contrast studies of 23 patients with complex forms of univentricular heart were compared with cineangiocardiographic findings obtained in traditional and axial projections. The morphology of the main ventricular chamber (left type 16, right 6, indeterminate 1), of the rudimentary chamber (16 anterior and four posterior), the type and modalities of atrioventricular connections (common AV valve 6, two AV valves 13, absent left connection 4), the connections and the interrelationships of the great arteries as well as the degree of obstruction of the outlet portions were analysed by both methods. M-mode echocardiography did not provide valuable information about atrioventricular valve morphology: in three cases discordant results were found. Contrast studies improved the diagnostic capabilities and allowed identification of double inlet connection in 10 out of 11 patients and of single inlet in four out of five patients respectively.

Adolescent↗

[Ostium secundum atrial septal defect: report of a case with atypical auscultatory findings (author's transl)].

The wide and persistent splitting of S2 is commonly considered the auscultatory hallmark of uncomplicated ostium secundum atrial septal defect (ASD). We have recently observed a 31-year-old female with a variable splitting of S2 and a 2/6 systolic murmur at the second left intercostal space, who showed incomplete right bundle branch block on the ECG and normal heart shadow with increased pulmonary vascular markings on the chest film. Cardiac catheterization revealed an isolated ostium secundum atrial septal defect with significant left-to-right shunt, normal pulmonary pressures and normal ventricular function. Subsequently the patient underwent closure with patch of the ASD without complications. We feel our case is of interest since it demonstrates that the absence of a wide and persistent splitting of S2 in adults does not exclude the diagnosis of uncomplicated "ostium secundum" ASD, when ECG and x-ray findings suggest the disease.

Adult↗

[The heart in myotonic dystrophy. Clinical and instrumental study in 17 patients (author's transl)].

17 patients with myotonic dystrophy have been studied. The skeletal muscle disease has been assessed by history, physical examination, electro-myography and muscle biopsy. Cardiac evaluation has been obtained by history, physical examination, chest X-ray, ecg at rest and after exercise, vectorcardiography and echocardiography. Only two patients presented symptoms and clinical findings of cardiac disease, otherwise conduction disturbances have been founded in 15 cases, pseudoinfarct pattern in 5 cases and loss of anterior vectors in 2 cases. Has to be remembered that in myotonic dystrophy sudden death has a very high incidence, which could be explained by the development of complete a-v block, because of the impairment of the conduction system. Therefore, in those patients with bifascicular blocks (3 cases), the electrophysiological study may be useful in order to evaluate the opportunity to put on a permanent pace-maker, to prevent sudden death.

Adolescent↗

[Coronary spasm during coronary arteriography. Classification and interpretative criteria].

Coronary spasm during selective coronary angiography have multiple explanation. In some instances there is no true pathological implication (catether induced spasm), in other instances, instead, a clear relationship with "functional" angina and myocardial infarction exists. Moreover, in few occasions may only be a false positive radiologic image (apparent spasm). The angiographic features of coronary spasm, however, are always the same, indipendently from its clinical significance and pathophysiologic mechanism. In this paper the Authors are not limiting their experience to the morphologic description of this event, rather describe the clinical criteria which, together with angiographic picture, may be useful in the interpretation of the physiopathology of the coronary artery spasm.

Angiography↗

Transient tricuspid insufficiency of the newborn. Report of a case and further considerations.

A case of transient tricuspid insufficiency in a newborn is reported. Cardiac catheterization performed at the age of two days because of cyanosis and cardiac failure, showed massive tricuspid incompetence, a normal tricuspid valve, increased diastolic volume of both ventricles valve, increased diastolic volume of both ventricles and depressed left ventricular ejection fractions. The clinical course has been satisfactory and at the age of four months repeated cardiac catheterization showed marked reduction of the size of both ventricles and improved left ventricular function; a small hypokinetic area of the left ventricle and a mild residual tricuspid incompetence, due to incomplete reversibility of the ischemic damage, were also documented. These findings suggest further considerations on therapeutic problems of transient tricuspid insufficiency and its outlook.

Female↗

[Traumatic tricuspid insufficiency. Clinical and therapeutic aspects. Report of three cases (author's transl)].

Three cases of traumatic tricuspid insufficiency are reported. The most consistent clinical and noninvasive cardiovascular findings were: previous nonpenetrating thorax trauma; non holosystolic murmur which increased slightly during inspiration on standing; electrocardiographic patterns of right atrial enlargement and right bundle branch block; unusual bulge along the mid-left heart border, seen on chest x-ray examination suggesting ventricular aneurysm; striking right ventricular dilatation wit paradoxical movement of the ventricular septum on ECHO. Cardiac catheterization led to definitive diagnosis by demonstrating a massive tricuspid valve incompetence with "ventricularisation" of the right atrial pressure. Some dyskinetic areas of the right ventrice, most likely due to the full-thickness contusion of the miocardial wall, seen on the right cineangiography, confirmed the diagnosis. The long-term clinical and haemodynamic follow-up was useful for monitoring the evolution of the disease. Surgery should be recommended in the presence of right-sided heart failure not relieved by adequate medical treatment, in view of the low operative risk.

Adult↗

[Aneurysmectomy and aortocoronary bypass. Immediate and long-term results of 56 patients].

56 pts. who underwent left ventricular aneurismectomy were studied. Clinical improvement and lat post-operatory mortality rate have been evaluated. 39 pts. (II group) also had aortocoronary bypass and other surgical procedures performed at the time of the aneurismectomy. Group I (no other surgery beside the aneurismectomy) and group II did not significant differences in the pre-operatory period and were, therefore, comparable. The total operatory mortality has been of 14% (17.6% in group I and 12.8% in group II). By using myocardial protection the mortality dropped to 5.8%. A significant difference between deceased and survived pts. was noted in the following parameters: cardiac index, A-V oxygen difference, extracorporeal circulation time and the number of diseased coronary arteries (P < 0.001-0.005). Only 2 pts., both in group II, had a late death. After the operation 32 pts. became asymptomatic. Five pts. remained symptomatic: 3 continued to complain of angina and 2 to show signs of left ventricular failure; ventricular arrhythmias were still present in 6 pts. post-operatively (compared to 16 pts. pre-op.). The data suggested that aneurismectomy, associated with aorto-coronary bypass and myocardial protection, has an acceptable operatory risk, particulary in pts. with a good residual ventricular function. Except for ventricular arrhythmias clinical results are very good and late mortality rate is low

Adult↗

[Atrial myxoma. Clinical, diagnostic, surgical and pathological features of 13 subjects (author's transl)].

The clinical, surgical and pathological features of 13 patients (3 males, 10 females) with cardiac myxoma are reported. Eleven masses were situated in the left atrium and 2 in the right one. The incidence of signs and symptoms usually ascribed to cardiac myxoma is evaluated. Particular emphasis is given to embolization phenomenon which occurred in 3 patients with villous-surfaced tumors. The results of phonocardiographic, echocardiographic and isotopic angioscintigraphic examination are illustrated and the use of these incruent investigations is highly recommanded. Final diagnosis may be achieved by cardiac catheterization and angiocardiography. Successful surgical excision was carried out in 12 patients. Structural profile of atrial myxoma is discussed. Particular attention is given to the surface of the tumors (smooth or villous), to the pseudovascular structures on the light microscopy and to the endotelial like features, together with secretory activity of the myxoma cells, on the electron microscopy. The morphologic findings support the neoplastic origin of the myxoma. The distinction between embolization and malignant metastasis is underlined.

Adult↗