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G Faust

Publications and source records attributed to G Faust.

36 records · Page 2Linked to original sources
PubMed1980

[On the synthesis of compounds with beta-adrenergic activity (author's transl)].

It is reported of the synthesis of 1-phenoxy-2-hydroxy-3-aminopropane derivatives with different substituents in the phenoxy residue as well as in the amino group. The potency and the efficacy of these derivatives depend on the substituents. By the introduction of the arylamino-ethyl residue into the nitrogen atom, beta-adrenergic locking agents with marked agonistic activity are obtained.

Adrenergic beta-Agonists↗
PubMed1980

[Derivatives of 6,7-dimethoxy-1-thiaisochroman-1,1-dioxide and 3.4-dihydro-6,7-dimethoxy-2H-1,2-benzothiazine-1,1-dioxide (author's transl)].

The authors deal with the synthesis of 3-substituted 6,7-dimethoxy-1-thiaisochroman-1,1-dioxide and 3,4-dihydro-6,7-dimethoxy-2H-1,2-benzothiazine-1,1-dioxide derivatives. The compounds in the first-named group were found to exert effects on the central nervous system, those produced by the basic amides being particularly marked, which differ from those of currently used psychopharmacological agents.

Amides↗
PubMedDate not supplied

[Biomechanical evaluation of the gliding nail in trochanteric fractures].

AIM: The purpose of the present study is to evaluate wether the gliding nail with it's double-t-shaped geometry is appropriate in the stabilization of unstable trochanteric fractures or not and if this evaluation can be performed with a static finite element simulation. METHODS: Surface-Reconstruction with CT database of a proximal femur and reconstruction with CT based density data was done. After modelling of geometry, isotropic material behaviour and load application during one leg standing in slow walking was done with a limited dataset of relevant muscles. Two relevant fractures are modelled. RESULTS: FE-simulation shows a movement of the femoral head distally, medially and posteriorly. Maximum bending strain is in the femoral diaphysis medial compression and lateral tension strain. In the proximal part we find a nearly homogeneous strain distribution. The clinical effect of lateralization of the proximal main fragment is also result of the simulation. In the area of the modelled fractures there is much more compressive stress than shear stress. CONCLUSION: Elastomechanical behaviour of the gliding nail is demonstrated with correlation of clinical observed effects. In both simulated fracture areas there is a bone union supporting compressive stress. This means in the FE-simulation the gliding nail is appropriate in the stabilization in unstable trochanteric fractures.

Biomechanical Phenomena↗