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Biomedical subjects

G Felsch

Publications and source records attributed to G Felsch.

At least 19 recordsLinked to original sources

[Possibilities of early diagnosis of left-heart insufficiency in acute myocardial infarction].

In 84 patients with an acute myocardial infarction clinical signs, measurement of the pressure of the pulmonary arteries and radiogramme of the thorax were used and compared for the estimation of the left heart insufficiency-particularly of an increase of a preload. The value of a standardized course series of radiogrammes of the thorax as a non-invasive investigation method in contrast to the invasive method of the pressure measurement of the pulmonary arteries was discussed. Advantages and disadvantages of the two methods were critically shown, since only in about 60% a correspondence was to be recognized.

Acute Disease

Screening for fra(X)(q) in a population of mentally retarded males.

Among 242 institutionalized mentally retarded males in Northern Germany screened for fra(X)(q), 15 (6.2%) with severe mental retardation expressing fra(X)(q) were detected. One patient displayed Klinefelter's syndrome in addition. All fra(X)(q) males showed the typical facial signs, but three of the adults did not express macroorchidism. A preliminary estimation of an overall frequency of 1:2000 males for the fra(X)(q) condition is suggested.

Adolescent

[Relation between atmospheric events and internal medicine emergency situations].

Over a period of 2,541 days (7 years) patients with the diagnosis groups acute oesophageal and gastrointestinal haemorrhage, respectively (n = 395), cerebrovascular insufficiency (n = 689) and acute myocardial infarction (n = 701) were registered. From the individual meteorological data registered in the same period the temperature the evaporation warmth of the water, the specific warmth capacity of the air, the air pressure and a constant calculation factor were used for the calculation of the equivalent temperature. Thus by its means a measure for the warmth content of the air was at our disposal which is determined by a series of factors. Between the emergency situations mentioned and the equivalent temperature established a correlation test for significance was performed. In these cases was the result that there are significant relations between the cerebrovascular insufficiency. Though already a larger number of meteorological parameters entered into our investigations, the result supposes that further important meteorological data should not be neglected, such as phases of weather and front transits. This shall be taken into consideration in future investigations.

Atmospheric Pressure

[Infusion therapy and parenteral feeding in acute pancreatitis].

The acute pancreatitis can be a life-threatening disease and can demand the performance of intensive-therapeutic measures. The central position there in occupy the infusion therapy and the parenteral nutrition. On account of the increased catabolism already in the initial phase of the acute pancreatitis the supply of suitable carriers of calories in adequate quantity is necessary. The indication of glucose and the differential indication of fructose and Alvesin "Neu" are discussed. In the treatment of shock human albumin, plasma and plasma substitutes as well as blood take the precedence. Apart from the diagnostic and therapeutic value of the peritoneal lavage in the acute pancreatitis is possesses the additional effect of the dialysis in acute renal failure.

Acute Disease

[Diagnosis and first aid in stroke during the prehospital phase].

In the GDR the apoplexy occupies the 4th place in the statistics of causes of death. It is an acute pathological process and has a firm place in emergency medicine (urgent home visit service and urgent medical aid). The symptomatology is multiform and under ambulatory conditions it may lead to considerable differential-diagnostic difficulties. In the present paper references are given taking into consideration the anamnesis (factors of risk), the clinical examination of the patient, first differential-diagnostic aspects, therapeutic methods resulting from this and suitable possibilities of hospitalisation.

Cerebrovascular Disorders

[Experiences with cytostatic treatment of malignant tumors].

The methods and the results of the cytostatic permanent and impact therapy, of the partial synchronisation as well as of the cytostatic combination treatment are described, taking into special consideration inoperable or metastasized solid tumours. From the study which was carried out during a period of 15 years results that a combination treatment referred in the individual doses to body weight and blood picture apparantly achieves better results than the other forms of therapy, whereby the risk of complications is relatively low.

Antibiotics, Antineoplastic

[Bases of medical treatment of acute poisonings].

The measures of the physician who is first in charge of the case often decisive for the course of the intoxication. Severe intoxication with disturbance of the vital functions immediately demand the removal of the acute danger to life. The effectivity of the detoxication treatment following the elementary therapy increases with the degree of exactness of the diagnosis. Therefore, already at the place of establishment the differential diagnostics of the cause of intoxication begins. To this belongs the asservation of poisons. In certain intoxications the detoxication is a constituent of the elementary therapy. Since only few antidotes are known the dominant factor of the detoxication treatment is above all in the unspecific detoxication treatment is above all in the unspecific detoxication. Its most important means are the prevention of the enteral resorption as well as forced renal elimination and dialysis. Experiences with barbiturate intoxications only with restriction are to be transmitted to other medicaments. Aslo among the groups of the barbiturates, the barbiturate-free sleeping drugs, the psychopharmaca, analgetics and others certain medicaments distinguish themseleves by characteristic effects which must be taken into consideration during treatment. Indication and differential indication of forced diuresis, haemodialysis and peritoneal dialysis are last not least determined by individual conditions and reactions on the part of the patient, concomitant diseases and complications. Taking into consideration the fact that a schematisation in detail is not to be proposed it is tried to derive and to prove recommendations for the medical action in acute intoxications.

Acute Disease

[Subclavian vein catheterization].

On the basis of experiences with more than 500 catherizations of the subclavian vein, which were performed partly infraclavicularly, partly supraclavicularly, the two methods were critically estimated and compared with regard to their effectivity and complications. The range of indications is enlarged from the access through the veins for taking blood samples and the infusion therapy over the measurement of the central venous blood pressure to the floating catheterization, temporary external pacemaker stimulation and emergency dialysis. The mastering of the two techniques of puncture provides a high measure of security for the emergency case. On the assumption of an approach secundum artem and knowing and taking into consideration the possibilities of complication, which are particularly referred to, the two ways seem to be approximately of the same value.

Catheterization

[Significance of the PV 1 index in the ECG of diabetes mellitus and in the early forms of chronic ischemic heart disease].

In 152 patients with diabetes mellitus, chronic ischaemic heart diseases and hypertension the so-called ptf-product resulting from the height of the amplitude of P and its time of spreading) measured in the lead V1 (PV1-index), was determined and compared with the values of 93 persons with healthy heart. Patients of the groups of diseases mentioned showed significantly higher pathological values than persons with healthy heart (limiting value -0.02 mms). A comparison between patients with chromic ischaemic heart disease at the age of 36-55 years and a group of diabetics of the same age without the clinical signs of an ischaemic heart disease resulted in no statistically ascertained differences. But compared with a group of persons with healthy heart of the same age the groups clearly differed: 63.9% of pathological values in the total group of disease compared with 18.5% of pathological values in persons with healthy heart. In 137 patients with latent diabetes (protodiabetes) in 54.7% also pathological ptf-values were found. It is possible that the determination of the ptf-product is able to ascertain already early forms of a chronic ischaemic heart disease still before its clinical manifestation. The large number of pathological values in patients with protodiabetes could be a first reference to early beginning disturbances of the left-sided atrial activity in the sense of a microangiopathy.

Adult