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Biomedical subjects

G Ferrito

Publications and source records attributed to G Ferrito.

12 recordsLinked to original sources
PubMed2001

Spinal vascular malformations: MR angiography after treatment.

PURPOSE: To evaluate the role of magnetic resonance (MR) angiography in the assessment of spinal vascular malformation therapy. MATERIALS AND METHODS: Thirty-four patients with spinal vascular malformations (30 dural arteriovenous fistulas, two perimedullary arteriovenous fistulas, and two intramedullary arteriovenous malformations) underwent MR angiography and MR imaging before and after endovascular or surgical treatment. RESULTS: MR angiography showed residual flow in perimedullary vessels in seven patients with dural fistula after embolization with liquid adhesive. In all seven, treatment failure was confirmed with arteriography. Long-lasting disappearance of flow in perimedullary vessels was demonstrated at MR angiography in 22 patients with dural fistula. MR imaging demonstrated normalization of spinal cord volume in 16 of 22 patients and signal intensity on T2-weighted images in three patients. Disappearance of cord enhancement was observed in five of 21 patients and of perimedullary enhanced vessels in six of 13 patients. In one additional patient with dural fistula treated with embolization, early posttreatment MR angiography showed disappearance of flow in perimedullary vessels, which reappeared at follow-up and was consistent with reopening of a small residual fistula. Posttreatment MR angiography demonstrated transient reduction of flow in the nidus in two patients with intramedullary malformations treated with embolization. Permanent disappearance of flow in the perimedullary vessel was seen after endovascular treatment in two patients with perimedullary fistula. CONCLUSION: MR angiography is more sensitive than MR imaging in depicting residual or recurrent flow in peri- or intramedullary vessels, which indicates patency of the vascular malformation.

Adolescent↗
PubMed1998

Posterior spinal artery infarct.

Acute medullary syndrome developed in a patient in whom glue had been inadvertently injected into the right posterior radiculomedullary artery during endovascular occlusion of a spinal dural arteriovenous fistula at T-11. MR imaging 40 days after the procedure showed signal changes and contrast enhancement in the posterior and right lateral column at T10-11. Circumscribed signal changes in the same areas without contrast enhancement were seen 4 months later. MR imaging was able to show this posterior spinal artery infarct.

Aged↗
PubMed1997

MRI and MR angiography of vertebral artery dissection.

A review of 4,500 angiograms yielded 11 patients with dissection of the vertebral arteries who had MRI and (in 4 patients) MR angiography (MRA) in the acute phase of stroke. One patient with incidental discovery at arteriography of asymptomatic vertebral artery dissection and two patients with acute strokes with MRI and MRA findings consistent with vertebral artery dissection were included. Dissection occurred after neck trauma or chiropractic manipulation in 4 patients and was spontaneous in 10. Dissection involved the extracranial vertebral artery in 9 patients, the extra-intracranial junction in 1, and the intracranial artery in 4. MRI demonstrated infarcts in the brain stem, cerebellum, thalamus or temporo-occipital regions in 7 patients with extra- or extra-intracranial dissections and a solitary lateral medullary infarct in 4 patients (3 with intracranial and 1 with extra-intracranial dissection). In 2 patients no brain abnormality related to vertebral artery dissection was found and in one MRI did not show subarachnoid haemorrhage revealed by CT. Intramural dissecting haematoma appeared as crescentic or rounded high signal on T1-weighted images in 10 patients examined 3-20 days after the onset of symptoms. The abnormal vessel stood out in the low signal cerebrospinal fluid in intracranial dissections, whereas it was more difficult to detect in extracranial dissections because of the intermediate-to-high signal of the normal perivascular structures and slow flow proximal and distal to the dissection. In two patients examined within 36 h of the onset, mural thickening was of intermediate signal intensity on T1-weighted images and high signal on spin-density and T2-weighted images. MRA showed abrupt stenosis in 2 patients and disappearance of flow signal at and distal to the dissection in 5. Follow-up arteriography, MRI or MRA showed findings consistent with occlusion of the dissected vessel in 6 of 8 patients.

Adult↗
PubMed1997

Identification of the feeding arteries of spinal vascular lesions via phase-contrast MR angiography with three-dimensional acquisition and phase display.

PURPOSE: To determine whether identification of the feeding arteries of spinal vascular lesions with phase-contrast MR angiography benefits from the higher spatial resolution of three-dimensional (volume) acquisitions and flow-direction information provided by the phase reconstruction of two-dimensional acquisitions. METHODS: Fifteen patients with high- or low-flow spinal vascular lesions proved by spinal arteriography underwent MR angiography with phase-contrast techniques. Arteriographic and MR angiographic studies were reviewed to identify the arterial feeders of spinal vascular lesions. RESULTS: On modulus reconstructions of coronal 2-D or 3-D acquisitions, three of four arteries feeding high-flow lesions and three of 14 arteries feeding low-flow lesions were identified as hypertrophic vessels joining the parent intercostal or cervical arteries. Of 11 intradural veins draining dural arteriovenous fistulas, three were identified on coronal 2-D acquisitions and six on coronal 3-D acquisitions as vessels that coursed from a neural foramen to a midline tangle of vessels. Phase reconstruction showed ascending and descending flow patterns in two patients with intramedullary arteriovenous malformations, and diverging flow in perimedullary veins draining a hemangioblastoma. In nine patients with dural arteriovenous fistulas, phase reconstruction provided information as to the level of the arterial feeders. Phase reconstruction in coronal plane acquisitions also provided evidence of centripetal flow. CONCLUSION: Three-dimensional acquisitions and phase display of 2-D acquisitions improved the visibility of arterial pedicles of spinal vascular lesions at phase-contrast MR angiography.

Adult↗
PubMed1995

MR angiography of spinal vascular malformations.

PURPOSE: To determine the potential and limitations of MR angiography in the evaluation of spinal vascular malformations. METHODS: Eleven consecutive patients with spinal vascular malformations proved with spinal selective arteriography underwent two-dimensional phase-contrast MR angiography. RESULTS: Abnormal vessels within the spinal canal were identified with MR angiography in 10 patients. In 1 patient with a dural arteriovenous fistula no definite vascular abnormality was seen with MR angiography. Correlation of MR angiography with spinal selective arteriography showed that the former allowed identification of the arterial feeder in 3 patients with intramedullary arteriovenous malformations and 2 with perimedullary arteriovenous fistula, whereas the source of intradural draining vein was seen in only 2 of 6 patients with dural arteriovenous fistula. CONCLUSION: MR angiography is a promising complementary tool to MR imaging for detection and characterization of spinal vascular malformations.

Adolescent↗
PubMed1994

Balloon occlusion of the carotid artery in the treatment of cavernous giant aneurysms: two cases.

Over recent years, endovascular occlusion of the carotid artery has become a valid alternative to its more traditional surgical ligation in the treatment of cavernous giant aneurysms. The authors report two cases treated with balloon occlusion in two patients with clinical signs of cavernous sinus syndrome. The procedure consisted of occluding the aneurysm and the carotid by means of detachable balloons. This was preceded by a 30-minute clinically monitored occlusion test aimed at evaluating the functioning of Willis' circle. The treatment was carried out under neuroleptoanalgesia, so optimal control of the neurological condition of the patient was possible. Partial symptom regression was obtained in both cases.

Aged↗
PubMed1994

Neuroma of the facial nerve masked by chronic otitis media.

The absence of facial twitching, weakness, or palsy makes the diagnosis of facial neuroma difficult. The authors report a case of neuroma of the horizontal portion of the facial nerve masked by the presence of a chronic ear. A woman with a long history of discharge and hypoacousia in her left ear presented with acute dizziness. Examination revealed grade 3 horizontal right nystagmus, left anacousia, and the appearance of an epitympanic cholesteatoma. Computed tomography (CT) was performed after the vestibular condition improved. The clinical diagnosis of chronic otitis media with cholesteatoma together with the radiologic finding of the mastoid and tympanic cavity completely occupied by soft tissue were enough to send the radiologist astray. The radiologic diagnosis confirmed that the bony destruction of the vestibule and lateral semicircular canal could be caused by a cholesteatoma. A neuroma of the horizontal portion of the facial nerve was discovered during surgery performed for the chronic ear. The postoperative study of the CT scans showed that there was no erosion of the malleus or incus, despite wide erosion of the vestibule and lateral semicircular canal. This finding would be enough to suggest the presence of pathology other than cholesteatoma. The patient refused exeresis of the neuroma. The authors recognize the difficulty in urging a patient to an operation that surely will result in worsening of the facial function. Follow-up in this case has revealed no change in tumor dimension or facial function over 3 years.

Cholesteatoma↗
PubMedDate not supplied

Contrast-enhanced time-resolved MR angiography of spinal vascular malformations.

PURPOSE: The purpose of this work was to assess the potential and limitations of a contrast-enhanced time-resolved MR angiography technique for evaluation of spinal vascular malformations. METHOD: Two patients with intramedullary arteriovenous (AV) malformations and three patients with dural AV fistula underwent four serial acquisitions, every 17-20 s, of 20-32 coronal 1.5- to 2-mm-thick partitions with a fast 3D SPGR sequence after injection of 0.2-0.3 mmol/kg paramagnetic contrast agent. This was followed by coronal 3D and sagittal or coronal 2D phase contrast (PC) MR angiography. RESULTS: No spinal vessels were visualized in the first (baseline) series. In patients with intramedullary AV malformations, the arterial feeders, nidus, and perimedullary draining veins were visualized in the second (early) series. In the third (intermediate) series, the arterial feeder vanished, whereas the intercostal and lumbar veins appeared. In patients with dural AV fistula, abnormal intraspinal vessel appeared in the third series and persisted, although less conspicuous, in the fourth (late) series. Contrast-enhanced time-resolved MR angiography demonstrated the venous components of the lesion with better conspicuity than 3D PC MR angiography, whereas it was inferior for visualization of arterial feeders. Moreover, indirect identification of the level of the dural AV fistula was possible only on the phase display of the 2D PC MR angiography. CONCLUSION: Contrast-enhanced time-resolved MR angiography is a useful complement to PC MR angiography for the evaluation of spinal vascular malformation.

Arteriovenous Fistula↗
PubMedDate not supplied

[Venous angioma associated with cavernous angioma. Presentation of three cases].

Cavernous angiomas and venous angiomas may be discovered as associated lesions in the same patient. Most Authors report that Venous angiomas are not true vascular malformation; they should be considered as variant of normal venous drainage, consisting of tortuous medullary veins converging into a dilated draining one. By rule, they are quite asymptomatic, and very rarely bleed. On the other side, cavernous angiomas are true vascular malformations, usually angiographically occult. Their association is relatively rare, but it is important because of the possibility of bleeding, which should be related to the presence of the cavernous malformation. We report the cases of three patients studied by Computed Tomography, Magnetic Resonance and Digital Angiography in our Neuroradiologic Department.

Adult↗
PubMedDate not supplied

Dural arteriovenous fistula at the craniocervical junction with perimedullary venous drainage.

MR imaging showed swelling and diffuse signal changes in the spinal cord in two patients with progressive myelopathy. MR angiography revealed slow-flow perimedullary vessels extending to the skull base, which are consistent with drainage vessels of a dural arteriovenous fistula at the craniocervical junction. This fistula was subsequently seen in both patients on selective arteriograms of the ascending pharyngeal and vertebral arteries.

Aged↗