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Biomedical subjects

G Findler

Publications and source records attributed to G Findler.

52 records · Page 3Linked to original sources

Transient global amnesia associated with a single metastasis in the non-dominant hemisphere. Case report.

A patient in whom transient global amnesia (TGA) led to the diagnosis of a metastasis of a transition-cell carcinoma of the bladder to the non-dominant hemisphere is described. In previously reported cases of TGA associated with brain tumors, the tumors involved either the dominant or both hemispheres. The etiology of TGA associated with a brain tumor is most likely vascular, as suggested by the sudden development and the transitory character of the event. In contrast to the "common" form of TGA (where both temporal lobes suffer temporary ischemia), in these patients only one side of the limbic system is affected, because a brain tumor has already compromised the other limbic area. Therefore, the dominance of the hemisphere with the tumor is of no consequence, as both hemispheres have been involved. It is concluded that the TGA in these patients is not due to, but is rather associated with, a unilateral brain tumor.

Aged↗

Trigeminal somatosensory evoked responses in patients with facial anaesthesia dolorosa.

The TSER of six patients with facial anaesthesia dolorosa showed shorter latencies and higher amplitudes of the late waves, which are believed to represent the processing of somatosensory input in the higher subcortical and cortical centres. Shorter latencies and higher amplitudes may reflect abnormal facilitation or decreased inhibition by these centres. The TSER also supplied an objective means of pain measurement, as the stimulating impulse at the affected side had to be reduced from 20 mA (the usual intensity used in patients without evoking pain or an unpleasant sensation) down to 9-12 mA, to avoid unbearable pain.

Adult↗

Somatosensory evoked potential to peroneal nerve stimulation in patients with herniated lumbar discs.

The somatosensory evoked potential (SEP) to peroneal nerve stimulation was recorded from 76 patients with myelographically proven herniated lumbar disc and was compared with normative data obtained from 65 healthy subjects. All patients with disc herniation had an abnormal SEP even when examination failed to disclose sensory deficits. In the patients with distortion of a root sleeve, the SEP abnormality was confined to the involved side. When myelography demonstrated large defects in the dural sac, there was electrophysiological evidence of disturbed conduction from the asymptomatic leg also. SEP changes in postoperative examinations correlated well with improvement or worsening of the patient's condition and enabled objective evaluation of the dynamics of sensory conduction along the involved structures.

Adolescent↗

Sensory evoked response to electrical stimulation of the trigeminal nerve in humans.

Electrical stimulation of the upper and lower lips of normal subjects evoked a consistent response recorded from over the face area of the ipsi- and contralateral hemispheres. This response consisted of seven discrete waves. Peak latencies ranged from as early as 8 msec to 115 msec. Stimulation of the lower lip evoked a response of lower amplitude and reversed polarity, as compared to te upper lip stimulation response. The data support the validity of the trigeminal sensory evoked response in the evaluation of the trigeminal pathways. Previously reported methods are reviewed and compared.

Adolescent↗

Reversible facial pain due to hydrocephalus with trigeminal somatosensory evoked response changes. Case report.

A patient with hydrocephalus due to aqueductal stenosis suffered facial pain which was relieved after the insertion of a ventriculoperitoneal shunt. The trigeminal somatosensory evoked response (TSER) of the affected side showed lower amplitudes and longer latencies as compared to the unaffected side. Following surgery, the waves regained higher amplitudes and shorter latencies. An episode of shunt malfunction was accompanied by recurrent facial pain and impairment of the TSER. Both improved after revision of the shunt. The possible etiology of facial pain in patients with hydrocephalus is discussed.

Adult↗

Chronic meningococcal meningitis in an infant.

The characteristic presentation of meningococcal meningitis is acute and clinically dramatic. This article describes an infant who presented with a bulging fontanelle and left arm weakness, but no signs of infection. Routine CT scan clearly showed hydrocephalus, but did not reveal the underlying ventriculitis which was subsequently disclosed by contrast enhancement. Subsequent CSF cultures grew Neisseria meningitidis.

Brain↗

Giant nevus of the scalp associated with intracranial pigmentation. Case report.

A case is reported of aggressive cellular blue nevus of the scalp. Intracranial pigmentation in association with a melanocytic nevus of the scalp may indicate either benign coexisting melanosis, local extension, or invasive malignancy. The importance of accurate diagnosis is discussed, and the need to be prepared to carry the excision deep enough to include the dura is illustrated.

Arachnoid↗

Neurogenic pulmonary edema associated with a colloid cyst in the third ventricle. Case report.

Neurogenic pulmonary edema (NPE) is usually the result of head trauma. The authors describe the case of a 13-year-old girl, in whom NPE was associated with a colloid cyst of the third ventricle causing acute hydrocephalus. The mechanisms involved in the development of NPE are briefly discussed. The possible role of the colloid cyst in the distortion of the anatomical relationships in the vicinity of the hypothalamic nuclei is considered.

Adolescent↗

Cranioplasty with pre-formed methyl methacrylate onlay plates.

The available manufactured plates for cranioplasty of large skull defects are not always satisfactory. Recently we have used preformed methyl methacrylate plates, in combination with Proplast. This plate prepared adjusted and sterilized before the operation is both cosmetically and mechanically satisfactory.

Adult↗

Transient hemiparesis: a rare manifestation of diphenylhydantoin toxicity. Report of two cases.

Among the common side effects of diphenylhydantoin (DPH) overdose, the most frequently encountered neurological signs are those of cerebellar dysfunction. Very rarely, the toxic neurological manifestations of this drug are of cerebral origin. Two patients are presented who suffered progressive hemiparesis due to DPH overdose. Both had brain surgery before DPH treatment. It is assumed that patients with some cerebral damage are liable to manifest DPH toxicity as focal neurological signs.

Adult↗