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Biomedical subjects

G Finzi

Publications and source records attributed to G Finzi.

48 records · Page 3Linked to original sources
PubMedDate not supplied

[Comparative study of the activity of several disinfectants against bacterial strains isolated in a hospital environment and of laboratory origin].

The activity of 7 active principles contained in several disinfectant solutions in various percentages, and in water and in alcohol, against 15 bacteria strains (9 of hospital origin and 6 cultured in the laboratory) was examined, using modified version of the contact test (employment of hospital strains, fixed high-level) charges of microbes, and short antiseptic-bacterium contact times).

Cross Infection↗
PubMedDate not supplied

[Experimental studies on the bactericidal activity of formaldehyde].

A modified version of the contact test was used to assess the activity of a 1.2% and a 2.4% aqueous solution of formaldehyde against 14 hospital and standard bacterial strains. Generally speaking, there was average antibacterial activity for contact times in the 15-30 min range, while excellent activity was observed when longer periods were employed.

Disinfectants↗
PubMedDate not supplied

[Recent findings on the bactericidal power of 2,4,4-trichloro-2'-hydroxydiphenyl ether].

The modified contact test has been used to examine the activity of a water solution of 2,4,4-trichloro-2'-hydroxy diphenyl ether at concentrations of 1% and 2% with respect to 14 hospital and standard bacterial strains. Results show that at the two concentrations used, excellent bactericidal activity is obtained for contact times of between 30" and 3' depending on the strain considered.

Animals↗
PubMedDate not supplied

[Antibacterial activity of disinfectant solutions containing quaternary ammonium compounds for the storage of surgical instruments].

A survey conducted among the health managements and dispensary services of all Italian hospitals showed that disinfectants containing quaternary ammonium salts were most commonly used for the disinfection and storage of surgical instruments (66% of frequencies). It was therefore decided to run in vitro tests on the bactericidal activity of some of the more frequently used substances containing one or more of these salts as their active principle. Five were therefore examined against 8 hospital and 4 lab strains, namely three aqueous solution: 1% benzalkonium chloride plus 1% ethylbenzalkonium chloride; 0.6% alkyldimethylbenzylammonium chloride, plus 0.185% diisobutylphenoxyethoxyethylbenzyl ammonium chloride monohdydrate and 0.133% diisobutylcresoxyethoxydimethylbenzyl ammonium chloride monohydrate; 0.1% dodecylbenzylammonium-N-diethyl alcohol chloride; and two alcoholic solutions: 0.1% alkyldimethylbenzylammonium chloride; 0.25% benzalkonium chloride (F.U.).

Bacteria↗
PubMedDate not supplied

[Behavior of disinfectant substances in comparisons of bacterial strains].

Following a brief of the main requisites of disinfectants, the solutions tested during research are listed: 1) Ethyl alcohol denatured at 70 degrees C. 2) A hydro-alcoholic solution of 0,20% Benzalkonium chloride (F.U.) in association with 0.15% 1-Benzyl-3 [3-Dimethylammoniopropoxy]-1 H-indazol HCl. 3) An acetonic hydro-alcoholic solution of 0.1% Benzoxonium chloride, a water solution of 1% Polyvinylpyrrolidone-iodine (P.V.P.-I), a water solution of 0.5% Chlorhexidine gluconate, and a hydro-alcoholic solution of 0.17% Benzalkonium chloride. The technique used (modified contact test) is illustrated and the results analysed in detail. The best results absolutely were obtained by applying Ethyl alcohol denatured at 70 degrees C and P.V.P.-I in a water solution at a concentration of 1%. Some problem must, however, be borne in mind when using such substances (first, denaturing of proteins, second, action curtailed by temperature). Best results among the Q.A.C. were obtained with the hydro-alcoholic solution of an association of 0.20% Benzalkonium chloride (F.U.) and 0.15% 1-Benzyl-3 [3-Dimethylammoniopropoxy]-1 H-indazol HCl.

Bacteria↗
PubMedDate not supplied

[Experimental tests of a microwave sterilization system].

Data obtained in our experiments indicate that the microwave sterilization system utilized may be considered as a practical and rapid method for decontaminating steel surgical instruments. For the tested organisms (7 Gram- and 2 Gram+ genera) a 3' exposure time to microwaves provides successful sterilization. Microwave irradiation also had a killing action against Bacillus subtilis spores. A study by SEM of microwave treated spores shows typical morphological alterations of spore surfaces.

Bacteria↗