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Biomedical subjects

G Fiore-Donno

Publications and source records attributed to G Fiore-Donno.

At least 55 records · Page 3Linked to original sources
PubMed1977

Collagen resorption by fibroblasts in human gingiva.

In the course of the extensive tissue remodeling occurring after flap surgery and during the subsequent gingival reattachment in man, numerous intracellular vacuoles were observed in fibroblasts of the lamina propria. These vacuoles contained one or several typical collagen fibrils and had either an electron-lucent matrix or contained an electron-dense material obscuring the fibrillar outlines and cross-striations.

Adult↗
PubMed1977

[The intraepithelial carcinoma of the mouth mucosa and its anatomo-clinical variants].

Contrary to common opinion the intraepithelial cancer of the buccal mucosa presents clinical symptoms, but they are discreet and different from those observed in an invasive carcinoma. Usually, there is leucoplakia with an erythema and an irregular keratosis or a punctuated one. There is an erythematous variation (Queyrat's erythroplasia) which is without keratinasation. Only histological evidence can confirm the diagnosis cancer. It should be differentiated against Bowen's disease and the light, intermediated and severe dysplasias.

Bowen's Disease↗
PubMed1977

[The contractile filament system of carcinoma cells. Immunofluorescent and electron microscopic study].

Recent research has shown that the cytoplasm of several varieties of non muscular cells contains contractile proteins similar to those of striated muscle (actin and myosin, with the control complex of troponin and tropomyosin). Using indirect immunofluorescent staining with specific antisera, the authors demonstrate that the cytoplasm of the cells of oral squamous cell carcinoma contains actin, myosin and actinin (tropomyosin seems to be lacking). They have found these contractile proteins inconstantly in various precarcinomatous states, but never in normal epithelium, except in a few basal cells. In electronic microscopy, these contractile proteins correspond to a network of microfilaments of 40-80 A, more rarely 100-120 A, Clearly different from tonofilaments, located mainly in the peripheral part of the cytoplasm, just under the plasmalemmal membrane. It is tempting to speculate that the occurence of a contractile filamentous apparatus in the cells of oral carcinomas--already described in skin and mammal gland carcinomas--allows to these cells amoeboid movements and active migration, which might to some extent explain their tendency to invade surrounding tissues and to produce metastasis.

Actinin↗
PubMed1976

[The evolution of implantology --trends toward a new concept].

The development if implantology during the recent years, relative to the tissue tolerance of various implant materials seems to have improved the chances of success. The disastrous results of prior years have been due to improper techniques leading to unstable biostability between tissue and implant material surface. This insufficiency of biocompatibility is not only biochemical, but also biomechanical as a consequence of very differing physical properties of osseous tissue and implant material. By increasing the surface of the implant material, making it porous, a penetration of fibres and a neoformation of bone could be observed. Thus a conjunctive attachment forms thus securing a closure of tissue around the emerging abutments. At this level, the implant must be considered under the periodontal angle. Marginal irritation must at any price be avoided, thus reducing the chance of epithelial growth into depth. Materials responding to the demands of biocompatibility are certain forms of porcelain, vitrified carbon, titanium, calcium aluminate.

Alveolar Process↗
PubMed1975

[Odontogenic keratocysts].

Keratocysts may develop from cellular multiplication, from recidivating growth of epithelial cells left after curettage, and they have an important potential growth, they can degenerate into malignancies. There are several etiological possibilities: tissues connected with crown formation, invagination of nucous epithelium, degeneration of follicular cysts producing keratin. The most important characteristic of these cysts is the frequent recidivation. Fron a clinical standpoint, they are classified as benign tumors. After enucleation, the walls of healthy tissue should be reduced, particularly in locations where the access of curettes is difficult. If necessary, apicetomy is performed in order to completely eliminate the cyst walls. Histological examination is mandatory. Finally, radiologic controls during at least six years should be made.

Adult↗