[Social medicine in urban regions].
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Biomedical subjects
Publications and source records attributed to G Flores-Izquierdo.
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Several techniques are used to detect rejection episodes in renal transplants; complexity renders these tests impractical for clinical use in most cases. This paper reports the results obtained in the study of urinary FDP, by counterimmunoelectrophoresis, in 50 healthy subjects and in 360 consecutive samples from 18 renal transplant recipients; urine specimens were examined daily for periods of time of up to 60 days post transplant. Endogenous creatinine clearance levels were also quantified. Our findings show that while in normal subjects negative tests were always obtained in kidney transplant patients, increased FDP excretion was found, with peak levels observed at least 24 hours before the decrease of glomerular filtration rates and clinical manifestations of acute rejection which subside with immunosuppression. Finally, urinary FDP excretion in the oliguric phase of post transplant acute renal failure was similar to that of patients where kidney transplants functioned without any evidence of rejection.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
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The results of the treatment with surgery and percutaneous transluminal angioplasty of the renal artery were evaluated in 63 adult patients of both sex, from 16 to 60 years old with renovascular hypertension due to fibromuscular dysplasia in 48 and to atherosclerosis in 15. The stenosis of the renal artery was unilateral in 47 patients and bilateral in 16. The surgical procedures more used were the aorto-renal bypass with saphenous vein in 22 patients and unilateral nephrectomy in 16. From 41 patients treated with surgery, the arterial hypertension was cure or improved after one year in 30 (73.1%). From 22 patients treated with angioplasty, cure or improved was obtained in 17 (77.2%). Satisfactory results were obtained in patients with fibromuscular dysplasia and unilateral stenosis, and poor results in atherosclerosis and bilateral stenosis, with both methods. It is concluded, that surgery and angioplasty are satisfactory therapeutic methods in the renovascular hypertension, principally when is unilateral and due to fibromuscular dysplasia.