[On the standardization of the exertion test in electrocardiography].
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Biomedical subjects
Publications and source records attributed to G Folli.
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Systolic time intervals at rest and after exercise were studied in 56 patients with essential hypertension. The patients were divided into groups according to the presence or absence at rest of electrocardiographic patterns of left atrial hypertrophy, and left ventricular strain. An impaired left ventricular function was shown, at rest and after exercise, in patients who had an electrocardiographic pattern of "left ventricular strain".
In order to compare the efficacy of beta-blocking, diuretics and ACE-inhibiting monotherapy in controlling the blood pressure increase to stress, a study was conducted on 30 subjects (10 treated with atenolol, 10 with hydrochlorothiazide/amiloride combination, 10 with enalapril) with mild or moderate essential hypertension whose resting blood pressures were normalised by therapy. In the 3 groups of subjects blood pressure values at rest, during mental stress, static and dynamic exercise did not significantly differ before antihypertensive therapy. Atenolol and enalapril significantly reduced systolic and diastolic pressure below pretreatment values throughout and immediately after each test, differing from diuretic therapy which did not show any significant reduction in diastolic rises at the peak of hand-grip or in both systolic and diastolic pressures at the highest work-loads during dynamic exercise. In the recovery period of the exercise cycle test diuretics also produced a later normalisation of diastolic pressure. In conclusion, beta-blockers and ACE-inhibitors seem to be more effective than diuretics in the control of the blood pressure response to stress in hypertensive patients, suggesting that these drugs are the first choice treatment of mild to moderate hypertension.
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