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Biomedical subjects

G Forck

Publications and source records attributed to G Forck.

At least 37 records · Page 2Linked to original sources

[Studies on antigenic relationship between grass- and cult. rye pollens by skin-test, RAST and RAST-inhibition-test in patients with pollinosis (author's transl)].

Skin tests on patients suffering from pollinosis suggest frequently an antigenic relationship between various grass and cult. rye pollens. This problem was further studied using both, RAST and RAST inhibition test. The tests were performed with commercial grass pollen discs as well as with self-prepared disc labeled with cult. rye pollens and a combination of various grass antigens. Good agreement was found between self-made and commercial (single antigen) grass pollen discs (95.9%). RAST and skin test correlated also extremely well (92.3%). Mutual inhibition between grass and cult. rye pollens was measured by RAST inhibition test using self-prepared discs. High antigenic relationship between grass and cult. rye pollens was found, however, it could be demonstrated that the antibody pattern varies and contains "grass specific" antibodies.

Antibody Specificity↗

[Allergic reactions of the mouth mucosa in patients wearing dental prostheses].

Due to the increase in the frequency of allergic disorders it is necessary also to consider allergic reactions in the case of unspecific lesions in the oral region. Intolerance of drugs, resins, and metals can be demonstrated by elimination and exposure tests, but also by epicutaneous tests. Diagnostic measures and therapy vary with the type of allergy in each case.

Anesthetics↗

[The serum concentration of vitamin A in patients with psoriasis vulgaris after oral administration of vitamin A palmitate].

After oral application of vitamin-A-palmitate in male patients with psoriasis we hourly estimated the serum concentration of vitamin A. With rapidly elevating the maximum vitamin A level was achieved in 3-4 hrs but redescended to the initial level within 24 hrs by an exponential decrease. The curve could be fitted to the "BATEMANfunction". The velocity contents k1 and k2 were calculated but were varied individually. The constant b, the time between oral application and the commencement of resorption, was estimated at 30-60 min. The chromatographical analysis of the total vitamin A in all patients yielded a unique ratio of vitamin A-alcohol, -acetate and -palmitate for each hour.

Acetates↗

[Serum picture of vitamin A in healthy persons following a vitamin A palmitate loading].

After oral consumption of 150 000 U vitamin A-palmitate the serum of eight healthy men was hourly determined for vitamin A-concentration. Rapidly ascending to a maximum within three to four hours the concentration returned exponentially to its normal fasting level after 24 hours. The curve could be adapted to the BATEMAN-function. The velocity constants k1 and k2 were equal except for one case. These results were opposite to earlier results of patients with psoriasis vulgaris.

Adult↗

[The importance of radio-allergo-sorbent-test in comparison with intracutaneous test in diagnosis of allergic diseases].

A comparison of clinical skin-tesing using the prick-test and the intracutaneous test with the radio-allergo-sorbent-test (RAST) in 167 patients with different immediate-type allergies showed concordant results in 75.7 per cent of the cases. In 20 per cent of the cases, the skin-test was positive while the simultaneous RAST was negative. Results in male and female patients did not show any important difference. The two test methods agreed well with selected antigens, e.g. grass-pollen, animal-epithelium, fungi and egg white; whereas, the two methods showed considerably different results using tree pollen and housedust as antigens.

Allergens↗