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Biomedical subjects

G Frascá

Publications and source records attributed to G Frascá.

4 recordsLinked to original sources
PubMed1983

Detection of lymphocyte subsets in renal graft biopsy by monoclonal antibodies.

Monoclonal antibodies were used to study infiltrating cell subpopulations in 12 graft biopsy specimens taken from 12 patients during rejection episodes. A preponderance of T lymphocytes in the renal interstitium was observed in most cases, with a higher percentage of suppressor/cytotoxic cells. No correlation was documented between the type and severity of rejection and the percentage of the various infiltrating cells.

Adolescent↗
PubMed1981

Long term study of mesangial proliferative glomerulonephritis with IgM deposits.

Twenty-six cases of Mesangial Proliferative Glomerulonephritis and diffuse IgM deposits were studied. Nine had nephrotic syndrome; 8 minimal urinary abnormalities; 7 asymptomatic proteinuria; 2 recurrent haematuria. Immunofluorescence revealed granular mesangial deposits in 14 cases and interrupted linear deposits in the others, chiefly along the capillary walls. In the latter group the clinical picture was mainly nephrotic syndrome or asymptomatic proteinuria. The clinical course is favourable: 7 cases recovered; 12 improved; 7 did not show any change. No progression of renal lesions was observed. Despite uniform histological features, this nephropathy is unlikely to be a unique disease, but in our opinion it should be considered separately from other glomerulopathies.

Adolescent↗