PubMed Health⌕ Search

Biomedical subjects

G Freilinger

Publications and source records attributed to G Freilinger.

At least 73 records · Page 4Linked to original sources
PubMed1976

[The effect of anti-inflammatory substances on free muscle transplants in the experimental animal (author's transl)].

The effect of repeated subcutaneous injections of hydrocortisone and phenylbutazone on connective tissue formation was investigated in free rat muscle transplants. The follow-up investigation took place 4 weeks after transplantation of the long extensor muscles of the digits to the vastus lateralis group of the rectus femoris muscle. Connective tissue measurements were performed on the basis of hydroxyproline determinations. It was observed that in the untreated transplant there is twice as much connective tissue (expressed as a percentage) as in the same muscle remaining in situ. Hydrocortisone did not reduce the amount of connective tissue in the transplant. Phenylbutazone reduced the amount of connective tissue by 27%. At the same time the total weight of the transplants treated with hydrocortisone and phynylbutazone was reduced by 15% and 33% respectively. Attention is drawn to the myotoxic properties of hydrocortisone and phenylbutazone. Hence, in spite of the inhibited connective tissue formation there is no improvement in muscle fibre regeneration and their use cannot be recommended.

Animals↗
PubMed1976

[Iatrogenic tissue damage and its treatment (author's transl)].

Modern medicine with its manifold therapeutic possibilites brings many side effects which might result in tissue damage. 8 cases of iatrogenic tissue damage seen over a period of 5 years are presented and discussed. Measures for correction and reconstruction are proposed.

Bone Nails↗
PubMed1976

[Scalp avulsion injuries (author's transl)].

In a recent scalp avulsion injury, the scalp should always be re-implanted without delay if at all available. Subsequent normal hair growth can hardly be expected, but at least an original skin replacement has been effected. The reconstruction of only a part of the scalp should be performed in such a way that the hairless area is situated in the centre. The surrounding hair will cover this centre part. Rotation flaps in the region of the scalp follow other rules than apply to all other areas of the body. If applied correctly, good results can be achieved because of the excellent blood supply.

Accidents↗
PubMed1976

[Biochemistry of benign-symmetrical lipomatosis (adenolipomatosis Launois-Bensaude, Madelung's disease)].

1. Total lipids, total cholesterol, cholesterol esters, phospholipids, triglycerides and free fatty acids as well as the fatty acids profiles of the different lipid classes were determined in serum, lipomatous and normal adipose tissue. Triglycerides were elevated in patient L's serum. The distribution of serum lipoproteins in this patient's serum showed a type IV according to Fredrickson. All other lipid parameters were within the normal range. Palmitoleic acid was increased nearly in all lipid fractions of the patients' sera as well as in the lipids of lipomatous subcutaneous adipose tissue. 2. The lipomatous adipose tissues of the patients showing no histological abnormalities revealed higher levels of cyclic AMP than normal subcutaneous adipose tissue. 3. Serum uric acid was normal (patient E.), between the normal and pathological range (patient L.) and elevated (patient W.). Urinary uric acid excretion was increased in all three patients. 4. 14C-glycine was overincorporated into urinary uric acid in all three patients. 5. Adenine phosphoribosyltransferase activities in the hemolysates were within the normal range. A decrease of hypoxanthine-guanine phosphoribosyltransferase activities could be demonstrated in two patients' (e., w.) erythrocytes. Erythrocyte phosphoribosylpyrophate synthetase activity was slightly increased in patient L.'s and twice the normal value in patient W.'s erythrocytes.

Adult↗
PubMed1975

A new technique to correct facial paralysis.

In two cases of unilateral ficial paralysis, the advanced atrophy of the muscles forced us to try a new technique for dynamin reanimation. To our knowledge, this has not yet been reported in the literaturel. The technique combines a free nerve graft across the face with a free muscle graft or a muscle flap. The result in both our cases was good.

Adult↗
PubMed1975

[The technic of "sensorimotor" differentiated fascicular suture of peripheral nerves].

A method for the differentiation of motor and sensory nerve fibres of mixed peripheral nerves is presented. This method is based on the different content of acetylcholinesterase in motor and sensory nerve axons. The median and ulnar nerves of 13 human cadavers were biopsied at the wrist within three hours post mortem. All specimens were stained after the method of KARNOVSKY. The axons of the motor nerve fibres with their high content of acetylcholinesterase thus were marked. In all the examined ulnar nerves the motor fibres were found in the ulnar part. They were different in size and figure. In the median nerves only 1 to 3 motor fascicles were found, which are localized in the palmar and radial section of the nerve. These motor fibres represent only a little part of the whole cross section of the median nerve. As a consequence of this method of differentiation between motor and sensory fibres the surgery of peripheral mixed nerves may be influenced.

Acetylcholinesterase↗
PubMed1975

[Muscular neurotisation in traumatic abducens paresis (A new method of operative treatment) (author's transl)].

Traumatic abducens pareses occur quite often. The methods of operation known until now often achieved no good functional result. Therefore the authors experimentally tried to reinnervate by means of "musculr neurotisation" in 10 rabbits an extraocular muscle previously denervated. After 6 months the histological examination revealed the presence of newly germinated medullated nerve fibers and motor end plates. This was the proof that eye muscles may be reinnervated. Consequently in 5 patients with traumatic abducens paresis an implantation of the inferior oblique muscle was done. The functional improvement secured by this method of operation which for the first time has been applied on the human eye was good, in some cases even extremely good, depending on the time elapsed between lesion and operation.

Animals↗