Possible errors in the ferrous sulfate dosimeter.
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Indicators and Reagents↗
Biomedical subjects
G Froese
Publications and source records attributed to G Froese.
The calculation of transmission through a photon beam attenuator using sector integration.
A calculational scheme is presented for the prediction of the transmitted fraction (TR) through an attenuator of known material and physical dimensions, at any point in a photon beam, for a beam of any shape or size. The method considers the total TR to be composed of scatter and primary components and computes the scatter component by sector integration. The input for the calculations consists of measured narrow- and broad-beam transmitted fractions through lead in air for various circular fields, thicknesses of the attenuator, and angles from the central axis, in a geometry approximating typical treatment conditions. The method has been tested for the case of a uniform half slab and a 45 degree wedge in a 4-MV photon beam. It was found that the use of TR values obtained by the above method reduced the maximum absorbed dose computation error from 8% computed with a commercially available algorithm to 3%, in a typical treatment setup. This method is generally applicable to any shaped attenuator such as a wedge or compensator covering whole or part of a radiation field.
Humans↗
Thermal dosimetry of spinal cord heating in the mouse.
Three systems for the localized heating of the spinal cord of the mouse have been evaluated by measuring the temperatures in the spinal canal (Tsp); at a reference location dorsal to the spine (Tdo), and by numerically calculating temperature distributions throughout two-dimensional transverse cross-sections through the middle of the heated region. The systems assessed were water bath heating alone, water bath-rf combination and rf heating alone with oblique, dorsally located electrodes. It has been established that (1) for all systems delta T (where delta T = Tdo-Tsp) decreased throughout a 1 h heating period-this was attributed to changes in blood flow; (2) there existed a considerable variation in the experimental value of delta T, particularly for rf heating. The resulting error in the estimation of Tsp from a measured value of Tdo can be reduced by making use of the observed correlation between delta T and the slope of a temperature decay curve measured at the beginning of the heating period; (3) rf alone best spares adjacent visceral and superficial tissues from significant elevation of temperature.
Animals↗