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G Fry

Publications and source records attributed to G Fry.

23 records · Page 2Linked to original sources
PubMed1976

Aberrations of spherocylindrical spectacle lenses.

A procedure has been developed for tracing a bundle of rays through and ophthalmic lens and a schematic eye with its primary line of sight pointed through various parts of the lens. A bundle of eight rays can provide data for assessing the quality of the image formed by such a system. To test the procedure and to generate data which can help in selecting a method for evaluating image quality, we selected a single lens as an example. The lens selected has a spherical back surface (-5.00 diopters) and a toric front surface (+15.00 diopters in the vertical and /10.00 diopters in the horizontal). It has a center thickness of 5 mm and glass of index 1.523. Spot diagrams were generated with the eye pointed in various directions through the ophthalmic lens. The data generated showed that peripheral bundles which fall between the principal meridians emerge as astigmatic bundles. This leads to the proposal that blur circle theory can be used for evaluating the quality of the optical image and that it suffices in the case of a spherocylindrical ophthalmic lens to base the tolerances for refractive power on measurements made in the principal meridians.

Astigmatism↗
PubMedDate not supplied

Properties of cultured endothelium from adult human vessels.

Endothelium was isolated from samples of aorta and vena cava obtained from cadaver donors at the time kidneys were harvested for transplantation. Digestion with collagenase and gentle swabbing were used to free the cells from the intimal surface. Low density seeding permitted isolation of individual colonies with typical endothelial morphology. Modified Medium 199 supplemented with 10%-20% human plasma-derived serum and an extract from the bovine hypothalamus (500 micrograms/ml) enabled subcultured colonies to grow to confluency when culture surfaces were coated with fibronectin (1 micrograms/cm2). The presence of Factor VIII antigen was demonstrated using an indirect immunofluorescence technique. A monoclonal antibody to cultured umbilical vein endothelium, specific for endothelium, reacted with the subcultured cells from the aorta and vena cava. Type IV procollagen, fibronectin, and thrombospondin were identified as labeled proteins secreted by cultures of adult endothelium that had been incubated with 3H-proline and 3H-glycine. When the cultured endothelium was used in a sodium-m-periodate stimulated T lymphocyte mitogenic culture system, the endothelium exhibited accessory cell function. Prostacyclin production stimulated by incubation with arachidonic acid and PGH2 was variable from vessel to vessel. However, average values were lower than normally seen with cultured primary umbilical vein endothelium.

Adult↗
PubMedDate not supplied

Imported schistosomiasis in Europe: sentinel surveillance data from TropNetEurop.

BACKGROUND: Schistosomiasis is a major parasitic disease, increasingly imported into temperate climates by immigrants from and travelers to endemic areas. METHOD: To generate valid data on imported infectious diseases to Europe and to recognize trends over time, the European Network on Imported Infectious Diseases Surveillance (TropNetEurop) was founded in 1999. Three hundred and thirty-three reports of schistosomiasis were analyzed for epidemiologic and clinical features. RESULTS: Male patients accounted for 64% of all cases. The average age of all patients was 29.5 years. The majority of patients were of European origin (53%). Europeans traveled predominantly for tourism (52%). Main reasons for travel for people from endemic areas were immigration and refuge (51%) and visits to relatives and friends (28%). The majority of infections were acquired in Africa; 92 infections were clearly attributable to Schistosoma haematobium, 130 to Schistosoma mansoni, and 4 to Schistosoma intercalatum. Praziquantel was the only treatment used. No deaths were recorded. CONCLUSION: TropNetEurop sentinel provides valuable epidemiologic and clinical data on imported schistosomiasis to Europe.

Adolescent↗
PubMedDate not supplied

Prevalence of hepatitis A IgG in Irish international travellers.

The authors have studied the sero-conversion levels of Irish international travellers over the past 6 years with regard to Hepatitis A IgG levels. The rate of sero-conversion is significantly associated with patient age (x2 = 77.8, df = 1, p < 0.0001). There was no significant difference in the antibody levels between males and females. The results show that a large proportion of younger people travelling to developing countries are unprotected against Hepatitis A. Also approximately 30% of travellers over the age of 40 years have not seroconverted from previous exposure and therefore remain at risk. The mortality associated with Hepatitis A is in high risk groups. Therefore vaccination should be considered.

Adult↗