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Biomedical subjects

G Frykman

Publications and source records attributed to G Frykman.

10 recordsLinked to original sources

The clinical significance of the palmaris longus tendon in the pathophysiology of carpal tunnel syndrome.

Carpal tunnel syndrome is associated with increased intracarpal canal pressure. The effect of tendon loading on intracarpal canal pressures is documented in biomechanical studies. Palmaris longus loading in wrist extension induces the greatest absolute increase in intracarpal canal pressure. Despite this fact, the palmaris longus is not yet a proven independent risk factor for the development of carpal tunnel syndrome. The purpose of this prospective clinical study was to assess and quantify the association between the presence of a palmaris longus tendon and carpal tunnel syndrome. Thirty-six carpal tunnel subjects with bilateral disease were compared with 36 controls. Each subject was clinically examined for the presence of the palmaris longus tendon. The prevalence of palmaris longus agenesis was significantly lower in the carpal tunnel group. The palmaris longus tendon is a strong independent risk factor for carpal tunnel syndrome.

Adult↗

Minima equalization: a useful strategy in automatic processing of microscopic images.

Specifically stained features in microscopic images rarely have a unique range of grey levels which would permit selection of the features by simple thresholding. The spaces between features and immediately surrounding them are often as dark or darker than the more lightly stained features. An algorithm for minima equalization which facilitates the extraction and segmentation of such features was designed and is explained in intuitive terms. It is applied to the analysis of cross-sections of peripheral myelinated nerve fibers. It is shown that the binary image obtained can be combined with a gradient image to give a binary image which accurately reflects the thickness of the myelin in the original image. Using silver-impregnated nerve endings and bile canaliculi stained for thiamine pyrophosphatase, binary images like those prepared manually from thick specimens using a camera lucida can be obtained using the minima equalization procedure. The image processor is used to develop a composite image by combining images at various focal planes through the thick specimen. This image is then processed to obtain the binary image.

Bile Canaliculi↗

Role of synovial fluid cells in the healing of flexor tendons.

A 1-cm segment of repaired rabbit flexor tendon was first subjected to 10,000 rads of x-radiation and then placed in the synovial cavity of a rabbit's knee joint. Macroscopic examination revealed healing at the repair site and rounding of the tendon ends without adhesions. Light- and electron-microscopic studies revealed cells resembling fibroblasts at the repair site and the periphery laying down collagen. Healing of this irradiated nonviable tendon was brought about by the cells present in the synovial fluid.

Animals↗